CAS 79831-76-8; (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine

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CAS:

79831-76-8

分子式:

C8H15NO4

分子量:

189.21

熔点:

213-217℃

英文名称:

(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine

(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine

1,6,7,8-indolizinetetrol, octahydro-, (1S-(1-alpha,6-beta,7-alpha,8-beta,8a-bet

(+)-castanospermine

7,8-indolizinetetrol, octahydro-, (1S,6S,7R,8R,8ar)-6

castanospermine

octahydro-1,6,7,8-indolizinetetrol (1S-(1-alpha,6-beta,7-alpha,8-beta,8a-beta

castanospermine from castanospermum australe seeds

用途:

Castanospermine可以抑制α- and β-glucosidases的所有形式，特别是glucosidase l.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

C860673

MACKLIN

亚胺糖栗树精胺

>98%

1035元/50mg; 2612元/250mg;

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储存：-20°C
状态：白色到灰白色粉末

942769

J&K

(+/-)-Castanospermine

95%

2577元/100MG;

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基本信息

分子式	C₈H₁₅NO₄
分子量	189.21
MDL编码	MFCD00017555

218775

Sigma-Aldrich

Castanospermine, Castanospermum australe-CAS 79831-76-8-Calbiochem

Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins.

968.64元/1 MG;

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产品说明

一般描述

Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins. Resulting oligosaccharides are primarily Glu₃Man_7-9 (GlcNAc)₂. Inhibits endothelial cell angiogenesis and tumor growth. Exhibits anti-viral properties. Typically used at 1-10 µg/ml.
Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins. Resulting oligosaccharides are primarily Glu₃Man_7-9(GlcNAc)₂. Reduces bFGF induced angiogenesis in mice. Inhibits endothelial cell migration and invasion of basement membrane. Exhibits anti-viral properties. Typically used at 1-10 µg/ml.

包装

1 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Primary Target
β-glucosidases
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Harmful (C)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Ahmed, S.P., et al. 1995. Biochem. Biophys. Res. Commun. 208, 267.
Pili, R., et al. 1995. Cancer Res.55, 2920.
Walker, B.D., et al. 1987. Proc. Natl. Acad. Sci. USA84, 8120.
Pan, Y.T., et al. 1983. Biochemistry22, 3975.
Saul, R., et al. 1983. Arch. Biochem. Biophys. 221, 593.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₈H₁₅NO₄
分子量	189.21
MDL编号	MFCD00017555

产品性质

质量水平	100
测定	≥98% (TLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated (hygroscopic)
颜色	white
溶解性	water: 1 mg/mL
运输	ambient
储存温度	2-8℃
InChI	1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s1
InChI key	JDVVGAQPNNXQDW-TVNFTVLESA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

532673

Sigma-Aldrich

(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine

98%

2679.74元/100 MG;

咨询

基本信息

经验(实验)分子式	C₈H₁₅NO₄
分子量	189.21
Beilstein	3588654
MDL编号	MFCD00017555
PubChem化学物质编号	24877905
NACRES	NA.22

产品性质

质量水平	100
测定	98%
旋光性	[α]20/D +80°, c = 0.9 in H₂O
mp	213-217 ℃ (lit.)
SMILES string	[H][C@]12[C@@H](O)CCN1C[C@H](O)[C@@H](O)[C@@H]2O
InChI	1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s1
InChI key	JDVVGAQPNNXQDW-TVNFTVLESA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

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