CAS 78628-80-5; 盐酸特比萘酚; terbinafine hcl

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

T831306

MACKLIN

盐酸特比萘芬

99%

48元/5g; 120元/25g; 426元/100g; 1507元/500g;

咨询

储存：室温,密封
状态：白色结晶粉末

T795438

MACKLIN

盐酸特比萘芬

10mM in DMSO

375元/1ml;

咨询

储存：-20°C

D2049

TCI

Terbinafine Hydrochloride

>98.0%(T)(HPLC)

190元/1G; 690元/5G;

咨询

基本信息

纯度/分析方法	>98.0%(T)(HPLC)
分子式/分子量	C₂₁H₂₅N・HCl = 327.90
外观与形状(20℃)	固体
相关CAS RN	91161-71-6
Reaxys-RN	5660449
PubChem物质ID	87568500
Merck Index (14)	9156
MDL编号	MFCD00145430

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(Nonaqueous Titration)	min. 98.0 %
Solubility in Methanol	almost transparency

物性(参考值)

熔点

214 ℃

相关法规

RTECS#

QJ8600100

547564

J&K

Terbinafine Hydrochloride

98%

656元/1G; 1986元/5G;

咨询

基本信息

分子式	C₂₁H₂₅N·HCl
分子量	327.90
MDL编码	MFCD00145430
Beilstein	5660449
Merck	14,9156

安全信息

图形或危害标志
提示语	Warning
危险说明	H315 H319 H335 H410
防范说明	P261 P273 P305+P351+P338 P501
UN号码	3077
危险分类	9
包装等级	III
WGK	3
RTECS	QJ8600100

C46126

Alfa Aesar

Terbinafine Hydrochloride

99%

1496元/1g; 5612元/5g;

咨询

基本信息

Ref#
46126

分子式
C21H25N.HCl

分子量
589.71

GHS危害和防范说明

GHS符号

Hazard Statements
H410
Very toxic to aquatic life with long lasting effects.

Precautionary Statements
P273 P391 P501

安全信息

危险等级
9

PHR1298

Supelco

Terbinafine Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

1162.78元/1 G;

咨询

产品说明

一般描述

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards. Terbinafine hydrochloride is an antifungal drug. Its mode of action involves the inhibition of squalene epoxidase enzyme, an essential component of fungal cell systems involved in ergosterol biosynthesis.
烯丙胺衍生物。

应用

Terbinafine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in drug dosage forms by UV spectrophotometry and high-performance thin layer chromatography (HPTLC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

作用方式：抑制角鲨烯环氧酶，防止麦角甾醇的生物合成。
抗菌谱：抗真菌和抗真菌。抗皮肤细胞和一些酵母的杀真菌剂；抗真菌白色念珠菌。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3257 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式	C₂₁H₂₅N · HCl
分子量	327.89
MDL编号	MFCD00145430
PubChem化学物质编号	329823287
NACRES	NA.24

产品性质

质量水平	300
等级	certified reference material pharmaceutical secondary standard
CofA	current certificate can be downloaded
technique(s)	HPLC: suitable gas chromatography (GC): suitable
application(s)	pharmaceutical (small molecule)
格式	neat
药典可追溯性	traceable to PhEur Y0000535 traceable to USP 1643496
储存温度	2-30℃
SMILES string	Cl[H].[H]\C(CN(C)Cc1cccc2ccccc12)=C(\[H])C#CC(C)(C)C
InChI	1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChI key	BWMISRWJRUSYEX-SZKNIZGXSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335 - H410
预防措施声明	P261 - P273 - P305 + P351 + P338 - P501
危险分类	Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0000535

Terbinafine Hydrochloride

European Pharmacopoeia (EP) Reference Standard

1559.78元/ ;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
烯丙胺衍生物。

生化/生理作用

作用方式：抑制角鲨烯环氧酶，防止麦角甾醇的生物合成。
抗菌谱：抗真菌和抗真菌。抗皮肤细胞和一些酵母的杀真菌剂；抗真菌白色念珠菌。

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₁H₂₅N · HCl
分子量	327.89
MDL编号	MFCD00145430
PubChem化学物质编号	329831006
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	Cl[H].[H]\C(CN(C)Cc1cccc2ccccc12)=C(\[H])C#CC(C)(C)C
InChI	1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChI key	BWMISRWJRUSYEX-SZKNIZGXSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335 - H410
预防措施声明	P273 - P302 + P352 - P305 + P351 + P338
危险分类	Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0001143

Terbinafine for system suitability

European Pharmacopoeia (EP) Reference Standard

1277.32元/ ;

咨询

产品说明

一般描述

烯丙胺衍生物。
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

作用方式：抑制角鲨烯环氧酶，防止麦角甾醇的生物合成。
抗菌谱：抗真菌和抗真菌。抗皮肤细胞和一些酵母的杀真菌剂；抗真菌白色念珠菌。

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₁H₂₅N · HCl
分子量	327.89
MDL编号	MFCD00145430
PubChem化学物质编号	329830783
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	Cl[H].[H]\C(CN(C)Cc1cccc2ccccc12)=C(\[H])C#CC(C)(C)C
InChI	1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChI key	BWMISRWJRUSYEX-SZKNIZGXSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335 - H410
预防措施声明	P305 + P351 + P338
危险分类	Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

T8826

Sigma-Aldrich

Terbinafine Hydrochloride

1525.25元/100 MG; 3298.24元/250 MG;

咨询

产品说明

一般描述

烯丙胺衍生物。

应用

盐酸特比萘芬是一种合成烯丙胺抗真菌剂。它用于治疗脚趾甲/手指甲、癣和股癣的皮肤真菌感染。它也用于吸附、分配和稳定性研究。

包装

100, 250 mg in poly bottle

生化/生理作用

特比萘芬抑制角鲨烯单加氧酶，从而阻断麦角甾醇的生物合成，麦角甾醇是真菌细胞膜的重要成分。角鲨烯单加氧酶的抑制也导致角鲨烯的积累。盐酸特比萘芬具有很高的亲脂性，易于积聚在皮肤、指甲和脂肪组织中，。它是抗真菌和霉菌的。它对皮肤细胞和一些酵母具有杀真菌作用，对白色念珠菌具有杀真菌作用。
作用方式：抑制角鲨烯环氧酶，防止麦角甾醇的生物合成。
抗菌谱：抗真菌和抗真菌。抗皮肤细胞和一些酵母的杀真菌剂；抗真菌白色念珠菌。

其他说明

保持容器密封，存放在干燥，通风良好的地方。保持干燥。

基本信息

经验(实验)分子式	C₂₁H₂₅N · HCl
分子量	327.89
MDL编号	MFCD00145430
PubChem化学物质编号	329826887
NACRES	NA.85

产品性质

质量水平	200
生物来源	synthetic
测定	≥98% (HPLC)
形式	powder
颜色	white
溶解性	methanol: soluble 50 mg/mL
作用机制	enzyme \| inhibits
抗生素抗菌谱	fungi yeast
SMILES string	Cl[H].[H]\C(CN(C)Cc1cccc2ccccc12)=C(\[H])C#CC(C)(C)C
InChI	1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChI key	BWMISRWJRUSYEX-SZKNIZGXSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335 - H410
预防措施声明	P273 - P302 + P352 - P305 + P351 + P338
危险分类	Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

1643496

USP

Terbinafine Hydrochloride

United States Pharmacopeia (USP) Reference Standard

3231.47元/200 MG;

咨询

产品说明

一般描述

烯丙胺衍生物。
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

作用方式：抑制角鲨烯环氧酶，防止麦角甾醇的生物合成。
抗菌谱：抗真菌和抗真菌。抗皮肤细胞和一些酵母的杀真菌剂；抗真菌白色念珠菌。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₁H₂₅N · HCl
分子量	327.89
MDL编号	MFCD00145430
PubChem化学物质编号	329751232
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	15-25℃
SMILES string	Cl[H].[H]\C(CN(C)Cc1cccc2ccccc12)=C(\[H])C#CC(C)(C)C
InChI	1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChI key	BWMISRWJRUSYEX-SZKNIZGXSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335 - H410
预防措施声明	P305 + P351 + P338
危险分类	Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

BP1159

Terbinafine Hydrochloride

British Pharmacopoeia (BP) Reference Standard

2144.18元/100 MG;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
烯丙胺衍生物。

生化/生理作用

作用方式：抑制角鲨烯环氧酶，防止麦角甾醇的生物合成。
抗菌谱：抗真菌和抗真菌。抗皮肤细胞和一些酵母的杀真菌剂；抗真菌白色念珠菌。

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₁H₂₅N · HCl
分子量	327.89
MDL编号	MFCD00145430
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	BP
格式	neat
储存温度	2-8℃
SMILES string	Cl[H].[H]\C(CN(C)Cc1cccc2ccccc12)=C(\[H])C#CC(C)(C)C
InChI	1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChI key	BWMISRWJRUSYEX-SZKNIZGXSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335 - H410
预防措施声明	P261 - P264 - P273 - P280 - P304 + P340 + P312 - P391
危险分类	Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

332489

Fluorochem

Terbinafine Hydrochloride

95%

220元/1g; 286元/10g; 572元/25g; 1672元/100g;

咨询

基本信息

CAS Number	78628-80-5
MDL Number	MFCD00145430

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H332: Harmful if inhaled. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .