CAS 785804-17-3; n-ac-dnal-dcpa-dpal-ser-nα-me-tyr-dasn-leu-ilys-pro-dala-nh2, acetate salt; abarelix acetate

CAS:

785804-17-3

中文名称:

n-ac-dnal-dcpa-dpal-ser-nα-me-tyr-dasn-leu-ilys-pro-dala-nh2, acetate salt

英文名称:

abarelix acetate

n-ac-d-nal-4-cl-d-phe-d-pal-ser-n-me-tyr-d-asn-leu-lys(ipr)-pro-d-ala-nh2, acetate salt

r3827 acetate

r-3827 acetate

n-acetyl-3-(2-naphthalenyl)-d-alanyl-4-chloro-d-phenylalanyl-3-(3-pyridinyl)-d-alanyl-l-seryl-n-methyl-l-tyrosyl-d-asparaginyl-l-leucyl-n6-(1-methylethyl)-l-lysyl-l-prolyl-d-alaninamide, acetate salt

ppi149 acetate

ppi-149 acetate

r 3827 acetate

ppi 149 acetate

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货号

品牌

产品名称

规格

包装、参考价格

SML2919

Sigma-Aldrich

Abarelix acetate

833.87元/5 MG; 3365.56元/25 MG;

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产品说明

生化/生理作用

Abarelix (PPI-149) is a gonadotropin releasing hormone (GnRH)/luteinizing hormone releasing hormone (LHRH) receptor (GnRHR, LHRHR) antagonist with low histamine release induction propensity (EC₅₀ = 100 μg/mL; rat mast cells). Abarelix exhibits good in vivo efficacy via iv. or sc. in suppressing LH levels in castrated male rats (plasma LH = 12/1.2/0.9/1.2 ng/mL 6 hrs post 0/12.5/50/200 μg/kg in 5% mannitol sc.) and in lowering testosterone among intact male rats (plasma testosterone = 1.64/0.29 ng/mL 6 hrs post 0/3 μg/kg sc.).

基本信息

经验(实验)分子式	C₇₂H₉₅ClN₁₄O₁₄ · xC₂H₄O₂
分子量	1416.06 (free base basis)

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	film or powder
颜色	white to beige
储存温度	−20℃

安全信息

象形图
警示用语：	Warning
危险声明	H361d
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable