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CAS: 7665-99-8
分子式: C10H12N5O7P
分子量: 345.20
英文名称: 
cyclic gmp
guanosine 3':5'-cyclic monophosphate*free acid
推荐供应商
货号品牌产品名称规格包装、参考价格
G920154MACKLIN鸟苷-3ˊ,5ˊ-环一磷酸98% (HPLC)1080元/5mg;   2290元/25mg;   3464元/100mg;   6326元/250mg;   咨询
储存:-20℃
状态:白色粉末
541344J&KGuanosine 3',5'-cyclic monophosphate98%1055元/10MG;   3674元/50MG;   咨询

基本信息

分子式C10H12N5O7P
分子量345.20
MDL编码MFCD00070129
EINECS 编号231-641-6
存储条件Freezer -20℃

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
G7504Sigma-AldrichGuanosine 3′,5′-cyclic monophosphate≥98% (HPLC), powder804.23元/5 MG;   2878.88元/25 MG;   9217.18元/100 MG;   咨询

产品说明

包装

5 mg in glass bottle
25, 100 mg in poly bottle

生化/生理作用

作为一种重要的第二信使,cGMP 是细胞外信号(如一氧化氮和利钠肽)的主要细胞内介质。环 GMP 与三种类型的细胞内受体蛋白相互作用:cGMP 依赖性蛋白激酶、cGMP 调节的通道和 cGMP 调节的环核苷酸磷酸二酯酶。体内 cGMP 水平升高的主要作用是刺激 cGMP 依赖性蛋白激酶 (PKG)。

特点和优势

该化合物是 ADME Tox 和环核苷酸研究的特色产品。发现更多特色 ADME Tox 和环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF G7504.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息,请访问sigma.com/metlin。

基本信息

经验(实验)分子式C10H12N5O7P
分子量345.21
EC 号231-641-6
MDL编号MFCD00070129
PubChem化学物质编号24895309

产品性质

质量水平200
测定≥98% (HPLC)
形式powder
颜色 white
溶解性0.2 M NaHCO3: 50 mg/mL
储存温度−20℃
SMILES stringNC1=NC(=O)c2ncn(C3OC4COP(O)(=O)OC4C3O)c2N1
InChI1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)
InChI keyZOOGRGPOEVQQDX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
329441FluorochemGuanosine 3',5'-monophosphate95%12342元/250mg;   41140元/1g;   咨询

基本信息

CAS Number7665-99-8
MDL NumberMFCD00070129

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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