CAS 73630-23-6; quin-2

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货号

品牌

产品名称

规格

包装、参考价格

08520

Sigma-Aldrich

Quin-2

suitable for fluorescence, ≥95% (HPLC)

4243.29元/50MG;

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产品说明

应用

Quin-2 has been demonstrated to be an indicator of Zn2+-protein complexes .

其他说明

A fluorescent highly selective Ca⁺⁺ indicator exhibiting fast uptake and release of Ca⁺⁺; Calibration substance in the measurement of cytoplasmic free calcium

基本信息

经验(实验)分子式	C₂₆H₂₃K₄N₃O₁₀
分子量	693.87
Beilstein	5374262
MDL编号	MFCD00065487
PubChem化学物质编号	329748596
NACRES	NA.32

产品性质

质量水平	100
测定	≥95% (HPLC)
溶解性	H₂O: 10 mg/mL
荧光	λ_ex 332 nm; λ_em 493 nm in 0.1 M Tris pH 8.0, 10 mM Ca²⁺
适用性	suitable for fluorescence
储存温度	2-8℃
SMILES string	[K+].[K+].[K+].[K+].COc1cc(N(CC([O-])=O)CC([O-])=O)c2nc(COc3cc(C)ccc3N(CC([O-])=O)CC([O-])=O)ccc2c1
InChI	1S/C26H27N3O10.4K/c1-15-3-6-19(28(10-22(30)31)11-23(32)33)21(7-15)39-14-17-5-4-16-8-18(38-2)9-20(26(16)27-17)29(12-24(34)35)13-25(36)37;;;;/h3-9H,10-14H2,1-2H3,(H,30,31)(H,32,33)(H,34,35)(H,36,37);;;;/q;4*+1/p-4
InChI key	XAGUNWDMROKIFJ-UHFFFAOYSA-J

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

551826

Sigma-Aldrich

QUIN 2, Tetrapotassium Salt-CAS 73630-23-6-Calbiochem

Binding of Ca²⁺ leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield.

6983.6元/50 MG;

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产品说明

一般描述

Binding of Ca²⁺ to QUIN 2 leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield. TPEN (Cat. No. 616394) can be used in conjunction with QUIN 2 to reduce heavy-metal quenching of QUIN 2 fluorescence in cells. Spectral properties in the presence of low calcium concentrations (ex. 354 nm, em. 510 nm) differ from those during high calcium conditions (ex. 332 nm, em. 505 nm).
Binding of Ca²⁺ leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield. TPEN (Cat. No. 616394) can be used in conjunction with QUIN 2 to reduce heavy-metal quenching of QUIN 2 fluorescence in cells.

包装

50 mg in Plastic ampoule

生化/生理作用

Primary Target
Calcium Probes
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Irritant (B)

重悬

Following reconstitution, aliquot and freeze (-20°C) under an inert gas, pH >10. Stock solutions are stable for up to 6 months at -20°C.

其他说明

Komada, H., et al. 1989. Cell Struct. Funct. 14, 141.
Vijayaraghavan, S. and Hoskins, D. 1989. Cell Calcium10, 241.
Arslan, P., et al. 1985. J. Biol. Chem.260, 2719.
Bryant, D.T. 1985. Biochem. J.226, 613.
Grynkiewicz, G., et al. 1985. J. Biol. Chem.260, 3440.
Ashley R.H., et al. 1984. Biochem. J.219, 149.
Tsien, R.Y., et al. 1982. J. Cell Biol.94, 325.
Tsien, R.Y. 1980. Biochemistry19, 2396.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₂₆H₂₃N₃O₁₀ · 4K
分子量	693.87
MDL编号	MFCD00065487

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze protect from light
颜色	yellow
溶解性	water: 10 mg/mL
荧光	λ_ex 332 nm (high) λ_ex 354 nm (low) λ_em 505 nm (high) λ_em 510 nm (low)
运输	ambient
储存温度	−20℃
InChI	1S/C26H27N3O10.4K/c1-15-3-6-19(28(10-22(30)31)11-23(32)33)21(7-15)39-14-17-5-4-16-8-18(38-2)9-20(26(16)27-17)29(12-24(34)35)13-25(36)37;;;;/h3-9H,10-14H2,1-2H3,(H,30,31)(H,32,33)(H,34,35)(H,36,37);;;;/q;4*+1/p-4
InChI key	XAGUNWDMROKIFJ-UHFFFAOYSA-J

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable