| CAS: | 728865-23-4 | |
| 分子式: | C24H27N3O5 | |
| 分子量: | 437.49 | |
| 英文名称: |
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| 用途: | CHIR-090是一种有效，缓慢，亲和力强的 LpxC 脱乙酰酶抑制剂。它与 E. coli LpxC 结合的 Ki 值为 4.0 nM。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||
| C877624 | MACKLIN | CHIR-090 | 99% | 88元/2mg; 167元/5mg; 566元/25mg; 956元/50mg; 2230元/250mg; | 咨询 | ||||||||||||||||||||||
储存：2-8℃ | |||||||||||||||||||||||||||
| SML3092 | Sigma-Aldrich | CHIR-090 | ≥98% (HPLC) | 1272.2元/5 MG; 5123.51元/25 MG; | 咨询 | ||||||||||||||||||||||
产品说明 生化/生理作用 CHIR-090 is a potent, tight-binding inhibitor against LpxC, the zinc-dependent UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase essential for gram negative bacteria lipid A biosynthesis (98% inhibition of E. coli & A. aeolicus LpxC by 0.5 μg/mL (1.15 μM) CHIR-090 at pH 7.4; A. aeolicus LpxC Ki = 1.0-1.7 nM). CHIR-090 possesses remarkable antibiotic activity comparable to that of ciprofloxacin against P. aeruginosa PAO1 as well as E. coli R477 and R477 [LpxC G17S] strains by antibacterial disk tests (20 μg/2 μL per spot). 基本信息
产品性质
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