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CAS: 72830-09-2
分子式: C8H10ClNO2 .HCl
分子量: 224.00
熔点: 155℃
中文名称: 
泮托拉唑的中间体
2-氯甲基-3,4-二甲氧基吡啶盐酸盐
英文名称: 
2-Chloro-3,4-dimethoxy pyridine HCL
2-chloromethyl-3,4-dimethoxy-pyridinium chloride
2-Chlormethyl-3,4-dimethoxypyridine hydrochloride
2-(Chloromethyl)-3,4-dimethoxypyridinium hydrochloride
2-(Chloromethyl)-3,4-dimethoxypyridine Hydrochloride
2-chloromethyl-3,4-dimethoxypyridine hydrochloride
性质描述: 该品为白色针状结晶。熔点152-157 ℃。
用途: 潘托拉唑中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
C806044MACKLIN2-(氯甲基)-3,4-二甲氧基吡啶 盐酸盐97%22元/1g;   26元/5g;   33元/25g;   129元/100g;   543元/500g;   咨询
储存:室温
状态:白色到灰白色粉末或晶体
C2073TCI2-(Chloromethyl)-3,4-dimethoxypyridine Hydrochloride>98.0%(T)250元/5G;   790元/25G;   咨询

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C8H10ClNO2・HCl = 224.08
外观与形状(20℃)固体
Reaxys-RN5360726
PubChem物质ID87558939
SDBS (AIST Spectral DB)51689
MDL编号MFCD02181083

技术规格

AppearanceWhite to Orange to Green powder to crystal
Purity(Nonaqueous Titration)min. 98.0 %
Purity(Argentometric Titration)min. 98.0 %

物性(参考值)

熔点150 ℃(dec.)
水溶性可溶

安全信息

图形或危害标志
信号词危险
危险性说明H302 + H312 : 吞咽或皮肤接触有害。
H315 : 造成皮肤刺激。
H318 : 造成严重眼损伤。
H317 : 可能造成皮肤过敏反应。
H411 : 对水生生物有毒并具有长期持续影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P273 : 避免释放到环境中。
P272 : 受沾染的工作服不得带出工作场地。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P391 : 收集溢出物。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P333 + P313 : 如发生皮肤刺激或皮疹:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P302 + P352 + P312 : 如皮肤沾染:用水充分清洗。如感觉不适,呼叫急救中心/医生。
P305 + P351 + P338 + P310 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。

运输信息

UN编号UN3077
类别9
包装类别 III
监管条件代码(*)
494284J&K2-(Chloromethyl)-3,4-dimethoxypyridine Hydrochloride98%136元/25G;   498元/100G;   咨询

基本信息

分子式C8H10ClNO2·HCl
分子量224.08
熔点155
MDL编码MFCD02181083
Beilstein5360726
EINECS 编号416-440-5

安全信息

图形或危害标志
提示语Danger
危险说明H302
H312
H315
H317
H318
H373
H411
防范说明P273
P280
P305+P351+P338
UN号码3077
危险分类9
包装等级III
WGK3
TSCA否
H60235Alfa Aesar2-Chloromethyl-3,4-dimethoxypyridine hydrochloride97%563元/1g;   2281元/5g;   咨询

基本信息

MDL
MFCD02181083

EINECS
416-440-5

分子式
C8H10ClNO2?HCl

分子量
224.08

熔点
155° dec.

形态
Solid

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H312-H315-H318-H317-H373-H411
Harmful if swallowed.Harmful in contact with skin.Causes skin irritation.Causes serious eye damage.May cause an allergic skin reaction.May cause damage to organs through prolonged or repeated exposure.Toxic to aquatic life with long lasting effects.

Precautionary Statements
P260-P280-P305+P351+P338-P310a-P301+P312a-P501a
Do not breathe dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
9

包装组
III

危险类别
21/22-38-41-43-48/22-51/53
Harmful in contact with skin and if swallowed.Irritating to skin.Risk of serious damage to eyes.May cause sensitization by skin contact.Harmful: danger of serious damage to health by prolonged exposure if swallowed.Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

安全等级
26-36/37/39-61
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.Avoid release to the environment. Refer to special instructions/safety data sheets.

欧盟危险品标志

TSCA
否

530301Sigma-Aldrich2-(Chloromethyl)-3,4-dimethoxypyridine Hydrochloride97%893.25元/25 G;   咨询

产品说明

一般描述

可使用麦芽酚作为起始材料合成2-(氯甲基)-3,4-二甲氧基吡啶盐酸盐(CDP)。CDP和DMS(硫酸二甲酯)可用于制备抗溃疡药泮托拉唑钠(PPS)。PPS中CDP和DMS的定量可通过气相色谱-质谱(GC-MS)同时进行。

应用

2-(氯甲基)-3,4-二甲氧基吡啶盐酸盐可用作制备[(2-吡啶基)-2-乙基]-[3,4-二甲氧基-(2-吡啶基甲基)]-N-甲胺的前体。

包装

25 g in glass bottle

基本信息

经验(实验)分子式C8H11Cl2NO2
分子量224.08
Beilstein5360726
EC 号416-440-5
MDL编号MFCD02181083
PubChem化学物质编号24877740
NACRESNA.22

产品性质

质量水平100
测定97%
mp155 ℃ (dec.) (lit.)
SMILES stringCl[H].COc1ccnc(CCl)c1OC
InChI1S/C8H10ClNO2.ClH/c1-11-7-3-4-10-6(5-9)8(7)12-2;/h3-4H,5H2,1-2H3;1H
InChI keyYYRIKJFWBIEEDH-UHFFFAOYSA-N

安全信息

象形图GHS05GHS07GHS08GHS09
警示用语:Danger
危险声明H302 + H312 - H315 - H317 - H318 - H373 - H411
预防措施声明P273 - P280 - P305 + P351 + P338
危险分类Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
211201Fluorochem2-(Chloromethyl)-3,4-dimethoxypyridinehydrochloride95%220元/1g;   374元/5g;   968元/25g;   2464元/100g;   咨询

基本信息

CAS Number72830-09-2
MDL NumberMFCD02181083

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H318: Causes serious eye damage.
H373: May cause damage to organs ..
H411: Toxic to aquatic life with long lasting effects.
防范说明 P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P272: Contaminated work clothing should not be allowed out of the workplace.
P273: Avoid release to the environment.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P314: Get medical advice/attention if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P322: Specific measures (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P333 + P313: If skin irritation or rash occurs: Get medical advice/attention.
P362: Take off contaminated clothing and wash before reuse.
P363: Wash contaminated clothing before reuse.
P391: Collect spillage.
P501: Dispose of contents/container to in accordance with local regulation .
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