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CAS: 70458-96-7
分子式: C16H18FN3O3
分子量: 319.34
熔点: 220°C
中文名称: 
氟哌酸
诺氟沙星
1-乙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-3-喹啉羧酸
英文名称: 
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxyl ic a
1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxyl ic a
am-715
baccidal
mk-366
norfloxacin
性质描述: 类白色至淡黄色结晶性粉末。熔点227-228℃。易溶于酸、碱溶液,极微溶于水和醇。无臭,味微苦。
用途: 氟哌酸昌日本杏林公司1978年开发的第三代喹诺酮类抗菌剂。具有抗菌谱广、抗菌力强的特点。对大肠杆菌、肺炎干菌、产气杆菌、阴沟杆菌、变形杆菌、沙门氏菌属、志贺氏菌属、枸橼酸杆菌属及沙雷氏菌属等遥植树菌科细菌具有强大的抗菌作用。临庆用于敏感菌所致泌尿系统、肠道、乎吸系统、外科、妇科、五官科及皮肤科等感受染性疾病。还应用于治疗淋病。
推荐供应商
货号品牌产品名称规格包装、参考价格
N794532MACKLIN诺氟沙星2mM in DMSO205元/1ml;   咨询
储存:-20°C
状态:液体
N814880MACKLIN诺氟沙星98%32元/1g;   45元/5g;   100元/25g;   274元/100g;   888元/500g;   3398元/2.5kg;   咨询
储存:2~8°C
状态:白色到黄色粉末
N0817TCINorfloxacin>98.0%(T)(HPLC)545元/5G;   1375元/25G;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C16H18FN3O3 = 319.34
外观与形状(20℃)固体
Reaxys-RN567897
PubChem物质ID125307523
SDBS (AIST Spectral DB)52829
Merck Index (14)6700
MDL编号MFCD00079532

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %

物性(参考值)

熔点221 ℃

相关法规

RTECS#VB2005000
309655J&KNorfloxacin98%456元/5G;   1188元/25G;   3564元/100g;   咨询

基本信息

分子式C16H18FN3O3
分子量319.33
熔点218-226
MDL编码MFCD00079532
Merck14,6700
EINECS 编号274-614-4
存储条件Store at 2-8℃

安全信息

防范说明P262
WGK2
RTECSVB2005000
TSCA
C44526Alfa AesarNorfloxacin98%, analytical standard3549元/5g;   咨询

基本信息

Ref#
44526

MDL
79532

分子式
C16 H18 F N3 O3

分子量
319.33

N9890SupelcoNorfloxacinanalytical standard, ≥98% (TLC)224.09元/1 G;   757.46元/5 G;   咨询

产品说明

一般描述

诺氟沙星 (Norfloxacin) 是一种广谱抗菌药物,对多种革兰氏阳性菌和阴性菌均有抗菌活性。
化学结构式:氟喹诺酮类

应用

参考产品的检验报告,了解更多关于合适仪器技术的信息。联系技术服务部寻求进一步支持。
诺氟沙星可作为标准品使用荧光分光光度法测定人血清样品中的诺氟沙星。

包装

1, 5 g in poly bottle

生化/生理作用

诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶(拓扑异构酶)复合物的结构转换而阻断 DNA 复制。
操作方式:抑制细菌 DNA 复制
抗菌谱:革兰阴性菌;对革兰阳性菌疗效较差

基本信息

经验(实验)分子式C16H18FN3O3
分子量319.33
EC 号274-614-4
MDL编号MFCD00079532
PubChem化学物质编号329818696
NACRESNA.24

产品性质

质量水平200
等级analytical standard
agencyEPA 1694
测定≥98% (TLC)
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)clinical testing
格式neat
储存温度2-8℃
SMILES stringCCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
InChI1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI keyOGJPXUAPXNRGGI-UHFFFAOYSA-N
Gene Informationhuman ... CYP1A2(1544)
rat ... Gabra1(29705)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
PHR1614SupelcoNorfloxacinPharmaceutical Secondary Standard; Certified Reference Material2391.32元/1 G;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Norfloxacin is a synthetic broad-spectrum antibacterial drug that is effective against various gram positive and gram negative bacteria. Its major application is in the treatment of urinary tract infections.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Norfloxacin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and serum samples by high performance liquid chromatography (HPLC) and spectrophotometric methods.

生化/生理作用

诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶(拓扑异构酶)复合物的结构转换而阻断 DNA 复制。
操作方式:抑制细菌 DNA 复制
抗菌谱:革兰阴性菌;对革兰阳性菌疗效较差

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC2802 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C16H18FN3O3
分子量319.33
EC 号274-614-4
MDL编号MFCD00079532
PubChem化学物质编号329823510
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 670
traceable to PhEur N1230000
traceable to USP 1471506
储存温度2-8℃
SMILES stringCCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
InChI1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI keyOGJPXUAPXNRGGI-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
N1230000NorfloxacinEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶(拓扑异构酶)复合物的结构转换而阻断 DNA 复制。
操作方式:抑制细菌 DNA 复制
抗菌谱:革兰阴性菌;对革兰阳性菌疗效较差

包装

Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C16H18FN3O3
分子量319.33
MDL编号MFCD00079532
PubChem化学物质编号329818530
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
InChI1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI keyOGJPXUAPXNRGGI-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
Y0001015Norfloxacin for system suitabilityEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶(拓扑异构酶)复合物的结构转换而阻断 DNA 复制。
操作方式:抑制细菌 DNA 复制
抗菌谱:革兰阴性菌;对革兰阳性菌疗效较差

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C16H18FN3O3
分子量319.33
MDL编号MFCD00079532
PubChem化学物质编号329831219
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
InChI1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI keyOGJPXUAPXNRGGI-UHFFFAOYSA-N
Y0001301Norfloxacin for peak identificationEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶(拓扑异构酶)复合物的结构转换而阻断 DNA 复制。
操作方式:抑制细菌 DNA 复制
抗菌谱:革兰阴性菌;对革兰阳性菌疗效较差

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C16H18FN3O3
分子量319.33
MDL编号MFCD00079532
PubChem化学物质编号329831351
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
InChI1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI keyOGJPXUAPXNRGGI-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
33899SupelcoNorfloxacinVETRANAL®, analytical standard1880.08元/100 MG;   咨询

产品说明

一般描述

诺氟沙星是一种抗菌药物,属于氟喹诺酮类(FQ),对多种革兰氏阴性和革兰氏阳性菌具有广谱抗菌活性。

应用

诺氟沙星可作为分析参考标准品,通过各种色谱技术对药物制剂、生物体液和污水中的分析物进行测定。
有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务。

生化/生理作用

诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶(拓扑异构酶)复合物的结构转换而阻断 DNA 复制。
操作方式:抑制细菌 DNA 复制
抗菌谱:革兰阴性菌;对革兰阳性菌疗效较差

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C16H18FN3O3
分子量319.33
EC 号274-614-4
MDL编号MFCD00079532
PubChem化学物质编号329754535
NACRESNA.24

产品性质

质量水平100
等级analytical standard
agencyEPA 1694
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)clinical testing
格式neat
储存温度2-8℃
SMILES stringCCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
InChI1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI keyOGJPXUAPXNRGGI-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 2
个人防护装备Eyeshields, Gloves, type N95 (US)
BP670NorfloxacinBritish Pharmacopoeia (BP) Reference Standard1861.35元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶(拓扑异构酶)复合物的结构转换而阻断 DNA 复制。
操作方式:抑制细菌 DNA 复制
抗菌谱:革兰阴性菌;对革兰阳性菌疗效较差

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C16H18FN3O3
分子量319.33
EC 号274-614-4
MDL编号MFCD00079532

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
SMILES stringCCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
InChI1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI keyOGJPXUAPXNRGGI-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
1471506USPNorfloxacinUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶(拓扑异构酶)复合物的结构转换而阻断 DNA 复制。
操作方式:抑制细菌 DNA 复制
抗菌谱:革兰阴性菌;对革兰阳性菌疗效较差

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C16H18FN3O3
分子量319.33
MDL编号MFCD00079532
PubChem化学物质编号329750584
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
InChI1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI keyOGJPXUAPXNRGGI-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
370848Fluorochem1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid95%286元/1g;   572元/5g;   1716元/25g;   5544元/100g;   咨询

基本信息

CAS Number70458-96-7
MDL NumberMFCD00079532

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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