CAS 70351-51-8; 超肉桂醛; supercinnamaldehyde

CAS:

70351-51-8

分子式:

C₁₂H₁₁NO₂

分子量:

201.22

中文名称:

超肉桂醛

英文名称:

supercinnamaldehyde

1,3-dihydro-1-methyl-3-(2-oxopropylidene)-2h-indol-2-one

用途:

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC50 = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

S921019

MACKLIN

超肉桂醛

≥98% (HPLC)

803元/5mg;

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储存：2-8°C
状态：粉末

S3322

Sigma-Aldrich

Supercinnamaldehyde

≥98% (HPLC)

1538.21元/5 MG; 6950.86元/25 MG;

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产品说明

应用

Supercinnamaldehyde may be used in transient receptor potential ankyrin 1 (TRPA 1)-mediated cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC₅₀ = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.

注意

Air-sensitive

基本信息

经验(实验)分子式	C₁₂H₁₁NO₂
分子量	201.22
MDL编号	MFCD08530327
PubChem化学物质编号	329824530
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	faintly red to very dark red
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃
SMILES string	CN1C(=O)C(=C\C(C)=O)\c2ccccc12
InChI	1S/C12H11NO2/c1-8(14)7-10-9-5-3-4-6-11(9)13(2)12(10)15/h3-7H,1-2H3/b10-7+
InChI key	CZKBLHCEDVWPRN-JXMROGBWSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves