| CAS: | 701213-36-7 | |
| 分子式: | C24H23N7O4 | |
| 分子量: | 473.48 | |
| 英文名称: |
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| 用途: | Temsavir (BMS-626529) 是一种 HIV-1 gp120 抑制剂，抑制其结合到 CD4+ T 细胞。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||
| T793082 | MACKLIN | Temsavir（BMS-626529） | 10mM in DMSO | 350元/1ml; | 咨询 | ||||||||||||||||||||||||||||||
储存：-20°C | |||||||||||||||||||||||||||||||||||
| T910357 | MACKLIN | Temsavir（BMS-626529） | 98% | 135元/10mg; 317元/25mg; 774元/100mg; | 咨询 | ||||||||||||||||||||||||||||||
储存：-20°C，密闭，干燥 | |||||||||||||||||||||||||||||||||||
| SML3186 | Sigma-Aldrich | BMS-626529 | ≥98% (HPLC) | 1076.74元/5 MG; 4337.05元/25 MG; | 咨询 | ||||||||||||||||||||||||||||||
产品说明 生化/生理作用 BMS-626529 is an HIV attachment inhibitor. HIV entry requires several steps in sequence starting with HIV surface protein gp120 binding to the CD4 receptor followed by a conformational change in gp120, eventually resulting in the fusion of HIV and the T cell membranes, allowing entry of the viral core into the cell. BMS-626529 prevents gp120 from binding to CD4. There is considerable heterogeneity within gp120 viral isolates. However, BMS-626529 was active against the majority of HIV-1 viruses with EC50 values <10 nM against most. Because of solubility problems, BMS-626529 is administered as its prodrug, BMS-663068. 基本信息
产品性质
安全信息
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