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CAS: 70-78-0
分子式: C9H10INO3
分子量: 307.08
熔点: 196-198℃
英文名称: 
3-Monoiodo-L-tyrosine
3-iodo-l-tyrosine
3-Iodo-tyrosine
推荐供应商
货号品牌产品名称规格包装、参考价格详情
I794200MACKLIN3-碘-L-酪氨酸10mM in Water529元/1ml;   展开
储存:-20°C
I811809MACKLIN3-碘-L-酪氨酸98%65元/1g;   256元/5g;   1168元/25g;   展开
储存:2~8°C
状态:白色到灰白色粉末
I0075TCI3-Iodo-L-tyrosine>98.0%(T)485元/1G;   1060元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C9H10INO3 = 307.09
外观与形状(20℃)固体
储存温度0-10℃
储存在惰性气体下存放于惰性气体之中
应避免的情况光,空气,加热
Reaxys-RN2941266
PubChem物质ID87571479
SDBS (AIST Spectral DB)4840
Merck Index (14)5047
MDL编号MFCD00002608

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Nonaqueous Titration)min. 98.0 %
Specific rotation [a]20/D-2.0 to -5.0 deg(C=2, 1mol/L HCl)
Solubility in Methanolalmost transparency

物性(参考值)

熔点199 ℃(dec.)
比旋光度 [α]D-3° (C=2,1mol/L Hcl)
351666J&K3-Iodo-L-tyrosine97%325元/1G;   1064元/5G;   展开

基本信息

分子式C9H10INO3
分子量307.08
熔点210
比旋光度([α]20D)-5° to -3° (C=5, 1 N HCl)
MDL编码MFCD00002608
Beilstein2941266
EINECS 编号200-744-8
存储条件Freezer -20℃

安全信息

防范说明P262
WGK3
H63789Alfa Aesar3-Iodo-L-tyrosine98%716元/1g;   3146元/5g;   展开

应用
3-iodo-l-tyrosine is used in the inhibition of tyrosine hydroxylase. 3-iodo-L-tyrosine is used in the rapid induction of prolactin secretion.

备注
Light Sensitive.Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light, heat.

基本信息

MDL
MFCD00002608

EINECS
200-744-8

分子式
C9H10INO3

分子量
307.09

熔点
210° dec

灵敏度
Store at -20°C. Light Sensitive.

形态
Powder

溶解性
Soluble in dilute aqeous acid and dilute aqeous base.

Beilstein
2941266

安全信息

TSCA

I8250Sigma-Aldrich3-Iodo-L-tyrosine808.42元/1 G;   2919.86元/5 G;   11191.3元/25 G;   展开

产品说明

一般描述

与二碘酪氨酸偶联的碘酪氨酸可合成 3,5,3′-三碘甲状腺原氨酸 (T3) 或 3,3′,5′-三碘甲状腺原氨酸 (rT3)。

应用

3-碘-L-酪氨酸已作为酪氨酸羟化酶的抑制剂用于 果蝇 和蚕蛹。

包装

1, 5, 25 g in poly bottle

生化/生理作用

3-碘酪氨酸 (3-IY) 抑制酪氨酸羟化酶,后者催化酪氨酸形成左旋多巴。严重甲减和甲状腺肿时,碘酪氨酸脱碘酶缺乏导致血清和尿中 3-IY 水平升高。
TH(酪氨酸 3-羟化酶)负责催化去甲肾上腺素能生物合成途径的第一步。TH 突变 与酪氨酸羟化酶缺乏相关,导致诸如婴儿型帕金森综合征和多巴( 多巴胺 )反应性肌张力障碍以及围产期发病的脑病。
酪氨酸羟化酶抑制剂。

基本信息

线性分子式IC6H3-4-(OH)CH2CH(NH2)CO2H
分子量307.09
Beilstein2941266
EC 号200-744-8
MDL编号MFCD00002608
eCl@ss32160406
PubChem化学物质编号24278154
NACRESNA.32

产品性质

质量水平200
杂质~5% tyrosine
mp210 ℃ (dec.) (lit.)
溶解性dilute aqueous acid: soluble
储存温度−20℃
SMILES stringN[C@@H](Cc1ccc(O)c(I)c1)C(O)=O
InChI1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1
InChI keyUQTZMGFTRHFAAM-ZETCQYMHSA-N
Gene Informationhuman ... TH(7054)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
M06129FluorochemH-Tyr(3-l)-OH95%286元/1g;   924元/5g;   1628元/10g;   3256元/25g;   6820元/100g;   展开

基本信息

CAS Number70-78-0
MDL NumberMFCD00002608

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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