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CAS: 70-49-5
分子式: C4H6O4S
分子量: 150.15
熔点: 152-155℃
中文名称: 
硫代苹果酸
硫羟苹果酸
巯基丁二酸
巯基琥珀酸
英文名称: 
mercapto-Butanedioic acid
mercapto-succinic aci
2-mercaptosuccinic acid
2-thiomalic acid
Butanedioic acid,mercapto-
mercapto-butanedioic aci
Mercaptobutanedioic acid
2-thio-malic aci
mercaptosuccinate
mercaptosuccinic acid
thiomalic acid
usaf ek-p-6297
usaf m-2
dl-mercaptosuccinic acid
展开更多英文名
性质描述: 无色结晶或白色粉末。熔点152-155℃。易溶于水、醇、醚及丙酮,几乎不溶于苯。水溶液遇三氯化铁显蓝色,但又很快消失。有硫化物的气味。
生产方法: 顺酐进行水合,生成顺丁烯二酸,再与硫化氢反应制得该品。实验室制备可将23.2g苹果酸、20g硫代乙酸溶于80ml乙酸乙酯中,回流1h。经冷却,加入400ml苯提取,加活性炭脱色,过滤除去炭,回收苯得粗品。经精制得32g乙酰基硫代苹果酸,熔点126℃。再进一步水解即得巯基丁二酸。
用途: 该品是冷烫剂的主要组分,还用于络合隐蔽、生化研究、重金属解毒剂及橡胶工业。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
M813490MACKLIN硫代苹果酸98%50元/5g;   138元/25g;   475元/100g;   2298元/500g;   11000元/2.5kg;   展开
储存:室温,密封
M0064TCIThiomalic Acid>98.0%(T)170元/25G;   525元/100G;   1390元/500G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C4H6O4S = 150.15
外观与形状(20℃)固体
Reaxys-RN1099858
PubChem物质ID87572177
SDBS (AIST Spectral DB)487
Merck Index (14)9343
MDL编号MFCD00004860

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(Neutralization titration)min. 98.0 %
Purity(Iodometric Titration)min. 98.0 %
Melting point152.0 to 155.0 ℃

物性(参考值)

熔点152 ℃
水溶性可溶
在水中的溶解度500 g/l   40 ℃
溶解性(可溶于)醇,丙酮
溶解性(微溶于)乙醚
溶解度(极微溶)

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#WM8225000
B23301Alfa AesarMercaptosuccinic Acid98%338元/25g;   800元/100g;   2758元/500g;   展开

应用
Mercaptosuccinic acid is used in the preparation of mercaptosuccinic acid diethyl ester by reaction with ethanol. It is also used as a brightening agent in metal plating. Further, it serves as an intermediate for the synthesis of corrosion inhibitors, soil fumigants, active pharmaceutical ingredients and electroplating agents.

备注
Incompatible with strong oxidizing agents and strong bases.

基本信息

MDL
MFCD00004860

EINECS
200-736-4

分子式
C4H6O4S

分子量
150.15

熔点
150-155°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in water, alcohol and acetone. Slightly soluble in ether. Insoluble in benzene.

Beilstein
1099858

Merck
14,9343

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
26-36/37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
WM8225000

TSCA

C12555Alfa AesarDL-Mercaptosuccinic acid99%727元/100g;   1946元/500g;   9572元/2.5kg;   展开

基本信息

Ref#
12555

MDL
4860

分子式
C4 H6 O4 S

分子量
150.15

形态
White powder

8.20763Sigma-AldrichMercaptosuccinic Acidfor synthesis531元/100 G;   展开

产品说明

分析说明

含量(碘量法): ≥ 98.0 %(a/a)
熔化范围(下限值): ≥ 151 °C
熔化范围(上限值): ≤ 154 °C
鉴定(IR):通过测试

基本信息

线性分子式HOOCCH2CH(SH)COOH
分子量150.15
MDL编号MFCD00004860
EC索引号200-736-4

产品性质

质量水平200
mp150-153 ℃
溶解性 500 g/L
储存温度2-30℃
InChI1S/C4H6O4S/c5-3(6)1-2(9)4(7)8/h2,9H,1H2,(H,5,6)(H,7,8)
InChI keyNJRXVEJTAYWCQJ-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
M6182Sigma-AldrichMercaptosuccinic Acid97%325.63元/25 G;   864.17元/100 G;   2918.06元/500 G;   展开

产品说明

一般描述

巯基丁二酸 (MSA) 是一种手性多功能中间体,在生物活性硫的合成中用作稳定剂 和封端剂。

应用

MSA 已被用于覆盖碲镉量子点 (QDs) 和纳米晶,应用范围广泛,如检测食品中的苯甲酸和总对羟基苯甲酸基防腐剂, 生物成像中的生物荧光标记 ,并可与生物医学应用中的抗体或抗原结合。MSA 可作为还原剂和表面改性剂包覆在金纳米粒子 (AuNPs) 上,在汞的荧光检测中具有潜在的应用价值。

包装

25, 100, 500 g in glass bottle

基本信息

线性分子式HOOCCH(SH)CH2COOH
分子量150.15
Beilstein1099858
EC 号200-736-4
MDL编号MFCD00004860
PubChem化学物质编号24897082
NACRESNA.23

产品性质

质量水平200
测定97%
mp155-157 ℃ (lit.)
SMILES stringOC(=O)CC(S)C(O)=O
InChI1S/C4H6O4S/c5-3(6)1-2(9)4(7)8/h2,9H,1H2,(H,5,6)(H,7,8)
InChI keyNJRXVEJTAYWCQJ-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
88460Sigma-AldrichMercaptosuccinic AcidReagentPlus®, ≥99.0% (HPLC)728.57元/100 G;   1839.28元/500 G;   展开

产品说明

一般描述

巯基丁二酸是一种亲水性巯基,吸附在 Au (Ⅲ) 表面后可形成硫苹果酸盐自组装单分子膜。

应用

巯基丁二酸被用作掺杂剂用于柠檬酸合成碳纳米点。它可以作为一种封端还原剂合成单层封端金纳米颗粒。

包装

100, 500 g in glass bottle

法律信息

ReagentPlus is a registered trademark of sigma-aldrich Co. LLC

基本信息

线性分子式HOOCCH(SH)CH2COOH
分子量150.15
Beilstein1099858
EC 号200-736-4
MDL编号MFCD00004860
PubChem化学物质编号57653308
NACRESNA.22

产品性质

质量水平200
产品线ReagentPlus®
测定≥99.0% (HPLC)
mp145-154 ℃
155-157 ℃ (lit.)
SMILES stringOC(=O)CC(S)C(O)=O
InChI1S/C4H6O4S/c5-3(6)1-2(9)4(7)8/h2,9H,1H2,(H,5,6)(H,7,8)
InChI keyNJRXVEJTAYWCQJ-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
358266Fluorochem2-sulfanylbutanedioic acid>98.0%(T)308元/25g;   990元/100g;   2926元/500g;   展开

基本信息

CAS Number70-49-5
MDL NumberMFCD00004860
Melting Point155-157℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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