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CAS: 68528-80-3
分子式: C16H20N2O8
分子量: 368.34
沸点: 513.5ºC at 760 mmHg
熔点: 169-170°C
英文名称: 
n-hydroxysuccinimide suberic acid ester
suberic acid bis(n-hydroxysuccinimide*ester)
用途: 具有胺反应性的同源双功能交联剂。通常通过缓冲到 pH 7.5 (6.5-8.5) 的酰胺键连接到含伯胺的分子上。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
S797829MACKLIN辛二酸双(N-羟基琥珀酰亚胺酯)10mM in DMSO420元/1ml;   展开
储存:-20°C
S822389MACKLIN辛二酸双(N-羟基琥珀酰亚胺酯)>98.0%(HPLC)(N)68元/1g;   210元/5g;   899元/25g;   3150元/100g;   展开
储存:2~8°C
状态:白色到灰白色粉末
D3895TCIDi(N-succinimidyl) Suberate>98.0%(HPLC)(N)450元/1G;   1390元/5G;   展开

基本信息

纯度/分析方法>98.0%(HPLC)(N)
分子式/分子量C16H20N2O8 = 368.34
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (分解)
Reaxys-RN3635296
PubChem物质ID87561635
MDL编号MFCD00049059

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(with Total Nitrogen)min. 98.0 %
Melting point169.0 to 173.0 ℃

物性(参考值)

熔点171 ℃
253405J&KDi(N-succinimidyl)suberate98%399元/1G;   1321元/5G;   展开

基本信息

分子式C16H20N2O8
分子量368.34
熔点166-170
MDL编码MFCD00049059
Beilstein3635296
存储条件Store at 2-8℃

安全信息

防范说明P262
WGK3
TSCA
H51771Alfa AesarDisuccinimidyl suberate97%1263元/250mg;   2141元/500mg;   3262元/1g;   展开

应用
Disuccinimidyl suberate is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm.

备注
Stable under recommended storage conditions. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00049059

分子式
C16H20N2O8

分子量
368.34

熔点
166-170°

灵敏度
Ambient temperatures.

形态
Crystalline

溶解性
Insoluble in water. Soluble in chloroform: 50 mg/mL.

安全信息

TSCA

C42602Alfa AesarSuberic acid bis(N-hydroxysuccinimide ester)97%3581元/1g;   13033元/5g;   展开

基本信息

Ref#
42602

MDL
49059

分子式
C16 H20 N2 O8

分子量
368.34

S1885Sigma-AldrichSuberic acid bis(N-hydroxysuccinimide ester)≥95%, powder991.88元/500 MG;   1263.72元/1 G;   3365.87元/5 G;   展开

产品说明

一般描述

辛二酸双(N-羟基琥珀酰亚胺酯)是具有胺反应性的同源双官能交联剂。通常与含有伯胺的分子,在 pH 7.5(6.5-8.5)的缓冲液中通过酰胺键偶联。辛二酸双(N-羟基琥珀酰亚胺酯)结合8原子连接体。

应用

辛二酸双(N-羟基琥珀酰亚胺酯)用于:

  • 对细胞裂解缓冲液进行补充,用于免疫沉淀
  • 将寡核苷酸标准品与明胶缀合
  • 交联ASC(凋亡相关斑点样蛋白,含胱天蛋白酶募集结构域)寡聚体

包装

500 mg in poly bottle
1, 5 g in poly bottle

基本信息

经验(实验)分子式C16H20N2O8
分子量368.34
MDL编号MFCD00049059
PubChem化学物质编号24899500
NACRESNA.21

产品性质

质量水平200
测定≥95%
形式powder
reaction suitabilityreagent type: cross-linking reagent
溶解性chloroform: 50 mg/mL
DMF: soluble
aqueous buffer: slightly soluble (may require 5-10% organic solvent in coupling mixture.)
储存温度2-8℃
SMILES stringO=C(CCCCCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O
InChI1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2
InChI keyZWIBGKZDAWNIFC-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
448714FluorochemBis(2,5-dioxopyrrolidin-1-yl) octanedioate95%242元/250mg;   528元/1g;   2002元/5g;   3190元/10g;   展开

基本信息

CAS Number68528-80-3
MDL NumberMFCD00049059
Melting Point166-170℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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