CAS 67035-22-7; dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate

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D914702

MACKLIN

2,6-二甲基-4-(2-硝基苯基)吡啶-3,5-二甲酸二甲酯

95%

893元/100mg; 1560元/250mg; 3928元/1g;

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储存：2-8°C
状态：淡黄色到黄色粉末

626583

J&K

Nifedipine EP Impurity A

98%

1995元/5MG; 9310元/25MG;

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基本信息

分子式	C₁₇H₁₆N₂O₆
分子量	344.33
熔点	100-105
MDL编码	MFCD00153847
存储条件	Freezer -20℃

安全信息

图形或危害标志
提示语	Danger
危险说明	H303 H318
防范说明	P280 P305+P351+P338

N0750010

Nifedipine impurity A

European Pharmacopoeia (EP) Reference Standard

1277.32元/ ;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

CYP3A4 nifedipine metabolite. Nifedipine (parent compound) is an antianginal and antihypertensive agent.

包装

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₇H₁₆N₂O₆
分子量	344.32
MDL编号	MFCD00153847
PubChem化学物质编号	329818456
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
SMILES string	COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c2ccccc2[N+]([O-])=O
InChI	1S/C17H16N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8H,1-4H3
InChI key	UMQHJQGNGLQJPF-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H318
预防措施声明	P280 - P305 + P351 + P338 + P310
危险分类	Eye Dam. 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable

UC167

Sigma-Aldrich

Oxidized Nifedipine

powder, ~95% (HPLC)

4429.58元/5 MG; 8153.66元/10 MG;

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产品说明

应用

Oxidized nifedipine has been used for apoptotic signaling studies in dopaminergic neurons.
Oxidized Nifedipine may be used:

to study enzyme kinetics using UV high-performance liquid chromatography (UV-HPLC)
as a standard in calibration curve preparation in high-performance liquid chromatography (HPLC) for the quantification of cytochrome P450 3A4 (CYP3A4)-mediated nifedipine oxidation in human microsomes
in nifedipine metabolism activity assay of Hep G2 cells transfected with hepatocyte nuclear factor-1α(HNF1α)

包装

5, 10 mg in glass bottle
Bottomless glass bottle. Contents are inside inserted fused cone.

生化/生理作用

Nifedipine is a dihydropyridine derivative and a calcium channel blocker. It is used in treating hypertension and angina pectoris. Oxidized Nifedipine is an oxidation product of nifedipine generated either by exposure to UV or day light. The enzyme cytochrome P450 3A (CYP3A4) metabolizes nifedipine.
CYP3A4 nifedipine metabolite. Nifedipine (parent compound) is an antianginal and antihypertensive agent.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. UC167.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式	C₁₇H₁₆N₂O₆
分子量	344.32
MDL编号	MFCD00153847
PubChem化学物质编号	329827652
NACRES	NA.77

产品性质

测定	~95% (HPLC)
形式	powder
颜色	yellow
mp	100-105 ℃
储存温度	2-8℃
SMILES string	COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c2ccccc2[N+]([O-])=O
InChI	1S/C17H16N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8H,1-4H3
InChI key	UMQHJQGNGLQJPF-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H318
预防措施声明	P280 - P305 + P351 + P338
危险分类	Eye Dam. 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

1463600

USP

Nifedipine Nitrophenylpyridine Analog

United States Pharmacopeia (USP) Reference Standard

11267.5元/25 MG;

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产品说明

生化/生理作用

CYP3A4 nifedipine metabolite. Nifedipine (parent compound) is an antianginal and antihypertensive agent.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₇H₁₆N₂O₆
分子量	344.32
MDL编号	MFCD00153847
PubChem化学物质编号	329750559
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
格式	neat
SMILES string	COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c2ccccc2[N+]([O-])=O
InChI	1S/C17H16N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8H,1-4H3
InChI key	UMQHJQGNGLQJPF-UHFFFAOYSA-N