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CAS: 67-45-8
分子式: C8H7N3O5
分子量: 225.160
熔点: 254-256°C (dec.)
中文名称: 
呋喃唑酮
痢特灵
3-(5-硝基糠叉氨基)-2-唑烷酮
英文名称: 
tikofuran
topazone
trichofuron
tricofuron
trifurox
usaf ea-1
viofuragyn
3-(5-Nitrofurfurylideneamino)-2-oxazolidinone
2-Oxazolidinone,3-[[(5-nitro-2-furanyl)methylene]amino]-
Furazolidone
furazolidone(not subject to
3-[[(5-nitro-2-furanyl)methylene]amino]-2-Oxazolidinone
furazolidone(not subject to fifra : 8709-e
Neftin
furazolidone(not subject to fifra : 8709-e pm24)
3-((5-nitrofurfurylidene)amino)-2-oxazolidinon
furazolidone(notsubjecttofifra:8709-e
3-(((5-nitro-2-furanyl)methylene)amino)-2-oxazolidinon
3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinon
3-(((5-nitro-2-furanyl)methylene)amino)-2-oxazolidinone
3-((5-nitrofurfurylidene)amino)-2-oxazolidone
3-((5-nitrofurylidene)amino)-2-oxazolidone
3-(5'-nitrofurfuralamino)-2-oxazolidone
5-nitro-n-(2-oxo-3-oxazolidinyl)-2-furanmethanimine
bifuron
corizium
diafuron
enterotoxon
furaxon
furaxone
furazol
furazolidon
furazon
furidon
furovag
furox
furoxal
furoxane
furoxon
furoxone
furoxone swine mix
furozolidine
giardil
giarlam
medaron
n-(5-nitro-2-furfurylidene)-3-amino-2-oxazolidone
n-(5-nitro-2-furfurylidene)-3-aminooxazolidine-2-one
nf 180 custom mix ten
nf-180
nicolen
nifulidone
nifuran
nitrofurazolidone
nitrofurazolidonum
nitrofuroxon
optazol
ortazol
puradin
roptazol
sclaventerol
展开更多英文名
性质描述: 黄色结晶性粉末。熔点275℃(分解)。极微溶于氯仿、水、乙醇和四氯化碳,1L水中溶40mg该品。稍溶于二甲基甲酰胺。无臭,味苦。
生产方法: 以乙醇胺为原料,与尿素缩合得到β-羟乙基脲,用亚硝化,环合得到3-亚硝基-2-唑烷酮。进一步用铁粉还原,再与5-硝基-2-糠二醇二乙酸酯及甲醛缩合,即得呋喃唑酮。
用途: 该品为具有较广抗菌谱的杀菌剂。作为抗感染类药物,对多种革兰氏阳性及阴性的大肠杆菌,炭疽杆菌,副伤寒杆菌等有效,用于治疗细菌性痢疾,肠炎,也有用于阴道感染,近年用于治疗伤寒,疗效较好。作为动物药品和饮料添加剂,对沙门氏菌,如小鸡白痢菌和大肠杆菌等具有特殊的抗菌作用,对原虫(球虫病菌等)也有一定作用,而且不易出现抗药性。呋喃唑酮少量用于基他应用领域(如水溶性涂料和纸浆)作杀菌剂。
推荐供应商
货号品牌产品名称规格包装、参考价格
F809764MACKLIN呋喃唑酮分析对照品, 98%(HPLC)398元/250mg;   咨询
储存:室温
状态:黄色 粉末
F794509MACKLIN呋喃唑酮10mM in DMSO185元/1ml;   咨询
储存:-20°C
F810004MACKLIN呋喃唑酮98%39元/2g;   88元/10g;   229元/50g;   820元/250g;   咨询
储存:2~8°C
状态:黄色粉末
F0821TCIFurazolidone>98.0%(HPLC)715元/25G;   咨询

基本信息

纯度/分析方法>98.0%(HPLC)
分子式/分子量C8H7N3O5 = 225.16
外观与形状(20℃)固体
Reaxys-RN384794
PubChem物质ID135727239
Merck Index (14)4300
MDL编号MFCD00910550

技术规格

AppearanceLight yellow to Amber to Dark green powder to crystal
Purity(HPLC)min. 98.0 area%

物性(参考值)

熔点257 ℃(dec.)
最大吸收波长365(DMSO) nm
水溶性微溶

安全信息

图形或危害标志
信号词警告
危险性说明H303 : 吞咽可能有害。
H317 : 可能造成皮肤过敏反应。
H341 : 怀疑可造成遗传性缺陷。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P272 : 受沾染的工作服不得带出工作场地。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P312 : 如感觉不适,呼叫急救中心/医生。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P333 + P313 : 如发生皮肤刺激或皮疹:求医/就诊。
P405 : 存放处须加锁。

相关法规

RTECS#RQ3675000
559614J&KFurazolidone98%294元/10G;   646元/25G;   2022元/100G;   咨询

基本信息

分子式C8H7N3O5
分子量225.16
熔点254-256
MDL编码MFCD00010550
Beilstein384794

安全信息

图形或危害标志
提示语Warning
危险说明H361
防范说明P281
WGK3
RTECSRQ3675000
B20834Alfa AesarFurazolidone98%2170元/25g;   4787元/100g;   18768元/500g;   咨询

应用
Monoamine oxidase inhibitor

基本信息

MDL
MFCD00010550

EINECS
200-653-3

分子式
C8H7N3O5

分子量
225.16

熔点
254-256° dec.

灵敏度
Light Sensitive. Ambient temperatures.

形态
Powder

GHS危害和防范说明

GHS符号

Hazard Statements
H303-H341
May be harmful if swallowed.Suspected of causing genetic defects.

Precautionary Statements
P201-P280-P202-P308+P313-P405-P501a
Obtain special instructions before use.Wear protective gloves/protective clothing/eye protection/face protection.Do not handle until all safety precautions have been read and understood.IF exposed or concerned: Get medical advice/attention.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
68
Possible risk of irreversible effects.

安全等级
36/37
Wear suitable protective clothing and gloves.

RTECS
RQ3675000

TSCA

R11952Alfa AesarFurazolidone,1000ppm440元/1ml;   咨询

安全信息

危险等级
3

46297SupelcoFurazolidoneVETRANAL®, analytical standard641.79元/250 MG;   咨询

产品说明

一般描述

Furazolidone is an effective antiprotozoal and antibacterial agent.

应用

Furazolidone may be used as a reference standard:

  • For the determination of the analyte in pharmaceutical formulations by second-derivative spectrophotometry.
  • For the determination of the analyte in animal feeds using liquid chromatography with ultraviolet and thermospray mass spectrometric detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C8H7N3O5
分子量225.16
Beilstein8317414
EC 号200-653-3
MDL编号MFCD00010550
PubChem化学物质编号329757127
NACRESNA.24

产品性质

质量水平200
等级analytical standard
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
抗生素抗菌谱Gram-positive bacteria
parasites
application(s)cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
格式neat
作用机制enzyme | inhibits
SMILES string[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1
InChI1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI keyPLHJDBGFXBMTGZ-WEVVVXLNSA-N

安全信息

象形图GHS08
警示用语:Warning
危险声明H361fd - H412
预防措施声明P201 - P202 - P273 - P280 - P308 + P313 - P405
危险分类Aquatic Chronic 3 - Repr. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
F9505Sigma-AldrichFurazolidone598.83元/10 G;   咨询

产品说明

应用

呋喃唑酮是硝基呋喃衍生物,具有抗原虫和抗菌活性。呋喃唑酮与细菌 DNA 结合,从而导致单胺氧化酶逐渐受到抑制。用于治疗厌食和拮抗家禽对硫胺素的利用 。呋喃唑酮增加鸡心肌细胞中对毒胡萝卜素敏感的 Ca 2+-atp 酶 。

包装

10, 25, 100 g in glass bottle

生化/生理作用

呋喃唑酮及其产生的自由基,可能与 DNA 结合并诱导交联。细菌 DNA 对本药特别敏感,从而导致细菌染色体的高水平突变(转换和颠换)。其作用机制使耐药生物体的发展最小化。呋喃唑酮是一种单胺氧化酶 (MAO) 抑制剂,用作 DNA 链间交联剂。

基本信息

经验(实验)分子式C8H7N3O5
分子量225.16
Beilstein8317414
EC 号200-653-3
MDL编号MFCD00010550
PubChem化学物质编号24894997
NACRESNA.85

产品性质

质量水平200
生物来源synthetic
形式powder
颜色 yellow
mp256-256 ℃
溶解性formic acid: 50 mg/mL
作用机制enzyme | inhibits
抗生素抗菌谱Gram-positive bacteria
parasites
SMILES string[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1
InChI1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI keyPLHJDBGFXBMTGZ-WEVVVXLNSA-N

安全信息

象形图GHS08
警示用语:Warning
危险声明H361
预防措施声明P281
危险分类Repr. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
PHR2598SupelcoFurazolidonePharmaceutical Secondary Standard; Certified Reference Material2295.35元/500 MG;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC6175 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C8H7N3O5
分子量225.16
Beilstein8317414
MDL编号MFCD00010550

产品性质

等级certified reference material
pharmaceutical secondary standard
描述Pharmaceutical Secondary Standard; Certified Reference Material
形式solid
包装pkg of 500 mg
药典可追溯性traceable to USP 1286800
储存温度2-30℃
SMILES string[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1
InChI1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI keyPLHJDBGFXBMTGZ-WEVVVXLNSA-N

安全信息

象形图GHS08
警示用语:Warning
危险声明H361
预防措施声明P201 - P308 + P313
危险分类Repr. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1286800USPFurazolidoneUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C8H7N3O5
分子量225.16
Beilstein8317414
MDL编号MFCD00010550
PubChem化学物质编号329749915
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES string[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1
InChI1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI keyPLHJDBGFXBMTGZ-WEVVVXLNSA-N

安全信息

象形图GHS08
警示用语:Warning
危险声明H361
预防措施声明P280
危险分类Repr. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
358121Fluorochem3-{[(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one>98.0%(HPLC)1100元/25g;   咨询

基本信息

CAS Number67-45-8
MDL NumberMFCD00010550
Melting Point257℃

安全信息

图形或危害标志
危险性说明 H317: May cause an allergic skin reaction.
H341: Suspected of causing genetic defects ..
H361: Suspected of damaging fertility or the unborn child ..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P261: Avoid breathing .
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear .
P281: Use personal protective equipment as required.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P321: Specific treatment (see . on this label).
P333 + P313: If skin irritation or rash occurs: Get medical advice/attention.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to local regulations..
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