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CAS: 6609-64-9
分子式: C2H4ClO3P
分子量: 142.48
沸点: 98-99℃(2
熔点: 11-14℃
中文名称: 
2-氯-1,3,2-二氧杂
乙二胺氯磷酸盐
氯磷酸亚乙烯酯
英文名称: 
2-Chloro-2-oxo-1,3,2-dioxaphospholane
Ethylene chlorophosphate
2-chloro-1,3,2-dioxaphospholane-2-oxide
2-Chloro-1,3,2-dioxaphospholane 2-oxide
推荐供应商
货号品牌产品名称规格包装、参考价格详情
E836678MACKLIN环氯磷酸乙烯酯95%45元/1g;   169元/5g;   698元/25g;   2400元/100g;   9415元/500g;   展开
储存:-20°C
状态:无色-非常淡黄色液体
C1250TCI2-Chloro-2-oxo-1,3,2-dioxaphospholane>95.0%(GC)(NMR)460元/5G;   1590元/25G;   展开

基本信息

纯度/分析方法>95.0%(GC)(NMR)
分子式/分子量C2H4ClO3P = 142.47
外观与形状(20℃)液体
储存温度<0℃
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (分解),加热
Reaxys-RN606582
PubChem物质ID87566269
MDL编号MFCD00043138

技术规格

AppearanceColorless to Almost colorless clear liquid
Purity(GC)min. 95.0 %
Purity(NMR)min. 95.0 atom%

物性(参考值)

沸点91 ℃/0.8 mmHg
比重1.55
折射率1.45

安全信息

图形或危害标志
信号词危险
危险性说明H314 : 造成严重皮肤灼伤和眼损伤。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P303 + P361 + P353 : 如皮肤(或头发)沾染:立即脱掉所有沾污的衣物。用水清洗皮肤/淋浴。
P301 + P330 + P331 : 如误吞咽:漱口。不要诱导呕吐。
P363 : 沾染的衣服清洗后方可重新使用。
P304 + P340 + P310 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。立即呼叫急救中心/医生。
P305 + P351 + P338 + P310 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。
P405 : 存放处须加锁。

运输信息

UN编号UN3265
类别8
包装类别 II
监管条件代码(*)
A18320Alfa AesarEthylene chlorophosphate95%966元/5g;   4386元/25g;   15859元/100g;   展开

应用
Ethylene chlorophosphate is used in the syntheses of 2-methacryloyoxyethylphophocholine, phosphatidylcholines, 2',3'-O-16-hentriacontanyliden-adenosine-5'-phosphocholine and hexadecylphosphocholine. It is also involved the synthesis of alpha-naphthylphosphorylcholine, which is used to detect phospholipase C activity. It is an important reactant for the synthesis of a zwitterionic silane, UV-polymerizable lipids utilizing Chabrier reaction and block copolymers of poly(aliphatic ester) clickable polyphosphoester.

备注
Store in cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with water and reacts violently.

基本信息

MDL
MFCD00043138

EINECS
229-560-6

分子式
C2H4ClO3P

分子量
142.48

熔点
12-14°

沸点
98-99°/2mm

闪点
>110°(230°F)

密度
1.56

折射率
1.4500

灵敏度
Store at -20°C. Moisture Sensitive. Store under Nitrogen.

形态
Liquid

溶解性
Miscible with water and chloroform.

Beilstein
606582

GHS危害和防范说明

GHS符号

Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
II

危险类别
14-34
Reacts violently with water.Causes burns.

安全等级
8-20-23-26-30-36/37/39-45-60
Keep container dry.When using do not eat or drink.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Never add water to this product.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

欧盟危险品标志

TSCA

C33206Alfa Aesar2-Chloro-1,3,2-dioxaphospholane-2-oxide95%1100元/5g;   4707元/25g;   14379元/100g;   展开

基本信息

Ref#
33206

MDL
43138

分子式
C2 H4 Cl O3 P

分子量
142.48

闪点
>110

密度
1.55

形态
Colorless liquid

安全信息

危险等级
8

包装组
II

377953Sigma-Aldrich2-Chloro-1,3,2-dioxaphospholane 2-oxide1208.83元/5 G;   展开

产品说明

一般描述

2-氯-1,3,2-二氧磷杂环戊烷 2-氧化物(COP)是一种环状氯磷酸盐试剂,可以通过与分子氧反应由 2-氯-1,3,2-二氧磷杂环戊烷制备。

应用

用于以下反应的反应物:

  • 合成氨基官能化杂化烃/氟碳双链磷脂
  • 通过 Chabrier 反应合成可紫外聚合的脂类化合物
  • 合成聚(脂肪族酯)与可点击多磷酸酯的嵌段共聚物
  • 在多壁碳纳米管表面上印迹分子识别位点,用于实际样品中胰岛素的电化学检测
  • 合成两性离子硅烷
  • 合成核-壳-电晕胶束,并通过可逆交联稳定化,用于胞内药物递送

2-氯-1,3,2-二氧磷杂环戊烷 2-氧化物可用于合成:
  • 2-甲基丙烯酰氧乙基磷酸胆碱
  • 米替福新(十六烷基磷酸胆碱,MT)类似物
  • 磷酸 2-三甲基氨基-乙基酯十一碳-10-烯基酯
  • 尿苷核脂,(2′,3′-O-16-三氯乙烯基-尿苷-5′-磷酸胆碱,PUPC)
  • 腺苷核内化合物,(2′,3′-O-16-三氯乙烯基-尿苷-5′-磷酸胆碱,PAPC)
  • 结构相关的磷脂,它们是构象限制的或柔性的
  • 卵磷脂

包装

5 g in glass bottle

基本信息

经验(实验)分子式C2H4ClO3P
分子量142.48
Beilstein606582
EC 号229-560-6
MDL编号MFCD00043138
PubChem化学物质编号24863533
NACRESNA.22

产品性质

质量水平200
杂质<10% 2-Chloro-1,3,2-dioxaphospholane
折射率n20/D 1.45 (lit.)
bp89-91 ℃/0.8 mmHg (lit.)
mp12-14 ℃ (neat) (lit.)
密度1.55 g/mL at 25 ℃ (lit.)
储存温度−20℃
SMILES stringClP1(=O)OCCO1
InChI1S/C2H4ClO3P/c3-7(4)5-1-2-6-7/h1-2H2
InChI keySBMUNILHNJLMBF-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H314
预防措施声明P280 - P305 + P351 + P338 - P310
危险分类Skin Corr. 1B
补充剂危害EUH014
储存分类代码8B - Non-combustible, corrosive hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
050029FluorochemEthylene chlorophosphate95%308元/1g;   1298元/5g;   4290元/25g;   展开

基本信息

CAS Number6609-64-9
MDL NumberMFCD00043138
Boiling Point184.08℃
Melting Point-15.84℃
Density1.55

安全信息

图形或危害标志
危险性说明 EUH014: Reacts violently with water.
EUH029: Contact with water liberates toxic gas.
H290: May be corrosive to metals.
H314: Causes severe skin burns and eye damage.
防范说明 P234: Keep only in original container.
P260: Do not breathe .
P264: Wash hands thoroughly after handling.
P280: Wear .
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment (see . on this label).
P363: Wash contaminated clothing before reuse.
P390: Absorb spillage to prevent material damage.
P405: Store locked up.
P406: Store in corrosive resistant/ container with a resistant inner liner.
P501: Dispose of contents/container to local regulations.
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