产品说明 包装 10, 50 mg in glass bottle 生化/生理作用 Dienogest is used to treat endometriosis. It might also help to decrease the levels of plasma estradiol by stimulating cell death of granulosa cells in the ovary.
Dienogest is a fourth-generation progestin, an orally active synthetic progestogen with approximately 10% of the relative affinity of progesterone, but has a very potent progestagenic effect in the endometrium with some antiandrogenic activity and without any androgenic, glucocorticoid or mineralocorticoid effects. It has been used alone or in combination as a contraceptive and to treat uterine fibroids. Dienogest inhibits ovulation primarily through peripheral action rather than by central action on gonadotrophin secretion. 基本信息 | 经验(实验)分子式 | C20H25NO2 | | 分子量 | 311.42 | | MDL编号 | MFCD00868356 | | PubChem化学物质编号 | 329825902 | | NACRES | NA.77 |
产品性质 | 质量水平 | 100 | | 测定 | ≥98% (HPLC) | | 形式 | powder | | 旋光性 | [α]/D -305 to -325°, c = 1 in dichloromethane | | 颜色 | white to beige | | 溶解性 | DMSO: 5 mg/mL, clear (warmed) | | 储存温度 | 2-8℃ | | SMILES string | O[C@@]1(CC#N)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3CC[C@@]21C)=O | | InChI | 1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1 | | InChI key | AZFLJNIPTRTECV-FUMNGEBKSA-N |
安全信息 | 象形图 |  | | 警示用语： | Warning | | 危险声明 | H361 | | 预防措施声明 | P280 | | 危险分类 | Repr. 2 | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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