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CAS: 65802-56-4
分子式: C4H5N3OS·H2O
分子量: 161.18
中文名称: 
4-氨基-6-羟基-2-巯基嘧啶单水合物
4-氨基-6-羟基-2-巯基嘧啶一水物
2-巯基-4-氨基-6-羟基嘧啶一水物
6-氨基-2-硫尿嘧啶一水物
4-氨基-6-羟基-2-巯基嘧啶
英文名称: 
4-Amino-6-hydroxy-2-mercaptoprimidine
6-Amino-2-mercapto-4-pyrimidinol monohydrate
4-Amino-6-hydroxy-2-mercaptopyrimidine
4-amino-6-hydroxy-2-pyrimidinethio monohydrate
4-amino-6-hydroxy-2-mercaptopyrimidine monohydrate
性质描述: 纯度为98%的商品,熔点>330℃。
生产方法: 氰乙酸乙酯与硫脲环合而得:将无水乙醇与乙醇钠加入干燥的反应罐,搅拌加热至76℃,投入硫脲,在回流滴加氰乙酸乙酯。加毕,保持回流4h,冷至30℃,过滤,得粗品。加3.5倍水溶解,投入活性炭脱色,过滤,滤液加热至90℃,搅拌滴加40%乙酸至pH4-5,冷却,过滤,得成品。
用途: 医药中间体。用于生产抗恶性肿瘤药6-巯嘌呤。
推荐供应商
货号品牌产品名称规格包装、参考价格
A832248MACKLIN4-氨基-6-羟基-2-巯基嘧啶 单水合物98%28元/5g;   50元/25g;   149元/100g;   673元/500g;   3090元/2.5kg;   咨询
储存:室温,干燥,密封
状态:灰白色到淡黄色粉末
A0791TCI4-Amino-6-hydroxy-2-mercaptopyrimidine Hydrate>98.0%(T)220元/25G;   咨询

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C4H5N3OS・xH2O = 143.16
外观与形状(20℃)固体
Reaxys-RN5795441
PubChem物质ID87562319
MDL编号MFCD00052384

技术规格

AppearanceWhite to Yellow to Orange powder to crystal
Purity(Neutralization titration)min. 98.0%(calcd.on anh.substance)
Watermax. 12.0 %

相关法规

RTECS#UW0495000
L01992Alfa Aesar4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate98+%484元/25g;   1628元/100g;   咨询

应用
4-Amino-6-hydroxy-2-mercaptopyrimidine is a novel, potent, and selective A3 adenosine receptor antagonists. It is also used as pharmaceutical intermediates.

备注
Store at 4?°C. Incompatible with oxidizing agents. Avoid excessive heat and light.

基本信息

MDL
MFCD00150556

EINECS
213-722-8

分子式
C4H5N3OS?H2O

分子量
161.19 (143.17anhy)

熔点
>300°

灵敏度
Ambient temperatures.

溶解性
Soluble in water and DMSO.

Beilstein
5795441

安全信息

RTECS
YQ8817000

TSCA

OTV000203Sigma-Aldrich4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrateAldrichCPR2336.77元/1 G;   咨询

产品说明

其他说明

Please note that sigma-aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. sigma-aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.
NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY; (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE; OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY; WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.

基本信息

经验(实验)分子式C4H5N3OS · H2O
分子量161.18
MDL编号MFCD00150556
PubChem化学物质编号329819172

产品性质

mp>300 ℃ (lit.)
SMILES stringO.NC1=CC(=O)NC(=S)N1
InChI1S/C4H5N3OS.H2O/c5-2-1-3(8)7-4(9)6-2;/h1H,(H4,5,6,7,8,9);1H2
InChI keyBWYGMIYEADAIGW-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
A57406Sigma-Aldrich4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate98%345.27元/25 G;   咨询

基本信息

经验(实验)分子式C4H5N3OS · H2O
分子量161.18
MDL编号MFCD00150556
PubChem化学物质编号24891014

产品性质

质量水平100
测定98%
mp>300 ℃ (lit.)
SMILES stringO.NC1=CC(=O)NC(=S)N1
InChI1S/C4H5N3OS.H2O/c5-2-1-3(8)7-4(9)6-2;/h1H,(H4,5,6,7,8,9);1H2
InChI keyBWYGMIYEADAIGW-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H319
预防措施声明P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
036345Fluorochem6-Amino-2-thiouracil monohydrate97%220元/1g;   220元/10g;   352元/25g;   902元/100g;   咨询

基本信息

CAS Number65802-56-4
MDL NumberMFCD00150556

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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