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CAS: 65-45-2
分子式: C7H7NO2
分子量: 137.14
沸点: 270 °C
熔点: 139-142℃
中文名称: 
2-羟基苯甲酰胺
水杨酰胺
2-羟基苄胺
邻羟基苯酰胺
英文名称: 
2-hydroxy-Benzamide
salicylamide
2-carbamoylphenol
2-hydroxybenzamide
acket
afko-sal
algamon
algiamida
allevin
amid kyseliny salicylove
amid-sal
amidosal
anamid
benesal
2-hydroxy-benzamid
o-hydroxy-benzamid
2-hydroxy-benzoic aci amide
cidal
dolomide
dropsprin
h.p. 34
Benzamide,2-hydroxy-
liquiprin
morsarinas
novecyl
o-hydroxybenzamide
ohb
oramid
panithal
raspberin
salamid
salamide
saliamid
saliamin
salicilamide
salicim
salicylamid
salicylic acid amide
salipur
salizell
salrin
salymid
samid
serramida
sr 4326
urtosal
2-hydroxy-benzamide
展开更多英文名
性质描述: 白色或微粉红色结晶性粉末。熔点140℃。易溶于热水、醇、醚和氯仿,微溶于冷水。28℃饱和水溶液的pH约为5。略有苦味。
生产方法: 将水杨酸甲酯和25%氨水于20℃密闭搅拌3h,再于30-40℃搅拌5h。将反应液冷却、酸化至pH3-4,即析出水杨酸结晶。工业生产中,也可在水杨酸的水溶液中加入焦亚硫酸钠,再通氨反应。收率90%以上。
用途: 该品为解热镇痛药,也用于制取邻乙氧基苯酰胺(即止痛灵)等药物。小鼠口服LD50为1.4g/kg。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
S817923MACKLIN水杨酰胺99%37元/100g;   99元/500g;   318元/2.5kg;   1139元/10kg;   1121元/12X500g;   展开
储存:室温
状态:白色到浅黄色粉末或晶体
S742932MACKLIN水杨酰胺Standard for GC, ≥99.8%(GC)58元/5g;   展开
储存:室温
状态:固体
S0006TCISalicylamide>98.0%(T)(HPLC)120元/25G;   505元/500G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C7H7NO2 = 137.14
外观与形状(20℃)固体
Reaxys-RN742439
PubChem物质ID87575637
SDBS (AIST Spectral DB)3451
Merck Index (14)8328
MDL编号MFCD00007978

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Melting point140.0 to 143.0 ℃

物性(参考值)

熔点140 ℃
沸点182 ℃/14 mmHg

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#VN6475000
271757J&KSalicylamide98%202元/250G;   662元/1KG;   2638元/5KG;   展开

基本信息

分子式C7H7NO2
分子量137.14
熔点140-144
MDL编码MFCD00007978
Beilstein742439
Merck14,8328
EINECS 编号200-609-3

安全信息

图形或危害标志
提示语Warning
危险说明H302
H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSVN6475000
A10797Alfa AesarSalicylamide98%477元/250g;   1562元/1000g;   6247元/5000g;   展开

应用
Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies. It is used as an analgesic and as an antipyretic.

备注
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00007978

EINECS
200-609-3

分子式
C7H7NO2

分子量
137.14

熔点
138-142°

沸点
181°/14mm

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water (2.06 mg/ml at 25°C), chloroform, dimethyl sulfoxide, alcohol, and methanol (100 mg/ml).

Beilstein
742439

Merck
14,8328

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
26-36/37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
VN6475000

TSCA

C22936Alfa AesarSalicylamide99%1128元/250g;   620元/5g;   1864元/1kg;   展开

基本信息

Ref#
22936

MDL
7978

分子式
C7 H7 N O2

分子量
137.14

形态
White cryst powder

860417Sigma-AldrichSalicylamide99%586.06元/100 G;   展开

基本信息

线性分子式2-(HO)C6H4CONH2
分子量137.14
Beilstein742439
EC 号200-609-3
MDL编号MFCD00007978
PubChem化学物质编号24888510
NACRESNA.22

产品性质

质量水平100
测定99%
mp140-144 ℃ (lit.)
SMILES stringNC(=O)c1ccccc1O
InChI1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
InChI keySKZKKFZAGNVIMN-UHFFFAOYSA-N
Gene Informationhuman ... AR(367)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHR1449SupelcoSalicylamidePharmaceutical Secondary Standard; Certified Reference Material1461.17元/1 G;   展开

产品说明

一般描述

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Salicylamide is an antipyretic and analgesic, frequently prescribed in combination with other related drugs.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Salicylamide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrofluorimetry, spectrophotometry and high-performance thin layer chromatography.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA2826 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式2-(HO)C6H4CONH2
分子量137.14
Beilstein742439
EC 号200-609-3
MDL编号MFCD00007978
PubChem化学物质编号329822609
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp140-144 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1608000
储存温度2-30℃
SMILES stringNC(=O)c1ccccc1O
InChI1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
InChI keySKZKKFZAGNVIMN-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
84230Sigma-AldrichSalicylamidepuriss., ≥99.0% (T)432元/50 G;   547.71元/250 G;   649.52元/1 KG;   展开

基本信息

线性分子式2-(HO)C6H4CONH2
分子量137.14
Beilstein742439
EC 号200-609-3
MDL编号MFCD00007978
PubChem化学物质编号329769292
NACRESNA.22

产品性质

等级puriss.
质量水平100
测定≥99.0% (T)
mp139-141 ℃
140-144 ℃ (lit.)
溶解性methanol: 0.1 g/mL, clear
SMILES stringNC(=O)c1ccccc1O
InChI1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
InChI keySKZKKFZAGNVIMN-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
1608000USPSalicylamideUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式2-(HO)C6H4CONH2
分子量137.14
Beilstein742439
MDL编号MFCD00007978
PubChem化学物质编号329751067
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp140-144 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringNC(=O)c1ccccc1O
InChI1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
InChI keySKZKKFZAGNVIMN-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P301 + P312 + P330 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
091532Fluorochem2-Hydroxybenzamide95%220元/100g;   1012元/500g;   展开

基本信息

CAS Number65-45-2
MDL NumberMFCD00007978

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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