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CAS: 64657-21-2
分子式: C22H34O7
分子量: 410.50
英文名称: 
6-Acetyl-7-deacetylforskolin
6β-Acetoxy-1α,7β,9α-trihydroxy-8,13-epoxy-labd-14-en-11-one
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货号品牌产品名称规格包装、参考价格详情
967323J&KIsoforskolin90%, 来源于鄂尔多斯半日花2700元/5MG;   展开

基本信息

分子式C22H34O7
分子量410.5
MDL编码MFCD00078929
SML2801Sigma-AldrichIsoforskolin≥95% (HPLC)841.96元/5 MG;   3504.34元/25 MG;   展开

产品说明

生化/生理作用

Isoforskolin is a naturally occurring diterpene with anti-inflammatory activity. It has been shown to downregulate the expression of proinflammatory compounds. In an experimental mouse model of Lyme Disease induced arthritis isoforskolin downregulated the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA). In a rat asthmatic model isoforskolin down-regulated production of transforming growth factor β1 (TGF-β1) and interleukin-1β (IL-1β) which was accompanied by inhibition of inflammation and airway remodeling.

基本信息

经验(实验)分子式C22H34O7
分子量410.50
MDL编号MFCD00078929

产品性质

质量水平100
测定≥95% (HPLC)
形式powder
旋光性[α]/D -8 to -5°, c = 0.5 in chloroform-d
颜色 white to beige
溶解性DMF:H2O (9:1): 2 mg/mL, clear
储存温度−20℃
SMILES stringCC(=O)O[C@@H]1[C@H](O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]3(C)[C@@H](O)CCC(C)(C)C13)C=C
InChI1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(28-12(2)23)17(26)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16?,17-,19-,20-,21+,22-/m0/s1
InChI keyCLOQVZCSBYBUPB-VDCUXWMXSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H312
预防措施声明P280 - P302 + P352 + P312 - P362 + P364 - P501
危险分类Acute Tox. 4 Dermal
储存分类代码11 - Combustible Solids
WGKWGK 3
PHL82566Isoforskolinphyproof® Reference Substance10125.6元/10 MG;   展开

产品说明

一般描述

This substance is supplied with certified chromatographic purity. The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式C22H34O7
分子量410.50
MDL编号MFCD00078929

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥90.0% (HPLC)
形式solid
manufacturer/tradenamePhytoLab
SMILES stringCC(=O)O[C@@H]1[C@H](O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]3(C)[C@@H](O)CCC(C)(C)C13)C=C
InChI1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(28-12(2)23)17(26)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16?,17-,19-,20-,21+,22-/m0/s1
InChI keyCLOQVZCSBYBUPB-VDCUXWMXSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H312
预防措施声明P280 - P302 + P352 + P312 - P362 + P364 - P501
危险分类Acute Tox. 4 Dermal
储存分类代码11 - Combustible Solids
WGKWGK 3
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