CAS 6202-23-9; d)cycloheptene-delta(sup 5)-gamma-propylamine, n,n-dimethyl-5h-dibenzo( hydr

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货号

品牌

产品名称

规格

包装、参考价格

C794691

MACKLIN

5-(3-二甲氨基亚丙基)-二苯并[a，d]环庚三烯盐酸盐

10mM in DMSO

615元/1ml;

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储存：-20°C

C838229

MACKLIN

5-(3-二甲氨基亚丙基)-二苯并[a，d]环庚三烯盐酸盐

98%

288元/1g; 976元/5g; 3238元/25g;

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储存：室温

C3157

TCI

Cyclobenzaprine Hydrochloride

>98.0%(T)(HPLC)

390元/1G; 1080元/5G;

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基本信息

纯度/分析方法	>98.0%(T)(HPLC)
分子式/分子量	C₂₀H₂₁N・HCl = 311.85
外观与形状(20℃)	固体
相关CAS RN	303-53-7
Reaxys-RN	6247987
PubChem物质ID	253661206
Merck Index (14)	2713
MDL编号	MFCD00079039

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(Nonaqueous Titration)	min. 98.0 %
Melting point	215.0 to 219.0 ℃

物性(参考值)

熔点	217 ℃
最大吸收波长	290 nm
水溶性	完全溶解
溶解性(易溶于)	乙醇,甲醇
溶解度(极微溶)	氯仿

安全信息

图形或危害标志
信号词	危险
危险性说明	H301 : 吞咽会中毒。
防范说明	P501 : 将内装物/容器送到批准的废物处理厂处理。 P270 : 使用本产品时不要进食、饮水或吸烟。 P264 : 作业后彻底清洗皮肤。 P301 + P310 + P330 : 如误吞咽：立即呼叫急救中心/医生。漱口。 P405 : 存放处须加锁。

相关法规

RTECS#

HP0875000

运输信息

UN编号	UN2811
类别	6.1
包装类别	III
监管条件代码(*)

278434

J&K

Cyclobenzaprine Hydrochloride

98%, 一种外周性的芳香族L-氨基酸脱羧酶(AAAD)或DOPA脱羧酶抑制剂

438元/1G; 1882元/5G;

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基本信息

分子式	C₂₀H₂₁N·HCl
分子量	311.85
熔点	217
MDL编码	MFCD00079039
Beilstein	6247987
Merck	14,2713
EINECS 编号	228-264-4

产品描述

Cyclobenzaprine HCl 是一种通过抑制痛觉发挥作用的肌肉松弛剂, 用于治疗肌肉痉挛。是5-HT2 receptor拮抗剂。

靶点（IC50 & Targe）

5-HT

参考文献

[1] Kobayashi H, et al. Eur J Pharmacol. 1996, 311(1):29-35.

安全信息

图形或危害标志
提示语	Danger
危险说明	H301 H312 H332
防范说明	P280 P301+P310
UN号码	2811
危险分类	6.1
包装等级	III
WGK	3
RTECS	HP0875000

C46625

Alfa Aesar

Cyclobenzaprine Hydrochloride

1129元/1g; 3761元/5g;

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基本信息

Ref#
46625

分子式
C20H21N.HCl

分子量
379.28

GHS危害和防范说明

GHS符号

Hazard Statements
H301
Toxic if swallowed.

Precautionary Statements
P264 P301+P330+P331 P405

安全信息

危险等级
6.1

C4542

Sigma-Aldrich

Cyclobenzaprine Hydrochloride

1596.03元/1 G; 6418.84元/5 G;

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产品说明

一般描述

Cyclobenzaprine is a tricyclic agent, which has anti-depressant and anti-cholinergic properties. It lowers the tonic somatic motor activity of motor neuron systems. Cyclobenzaprine prevents the uptake of noradrenaline. It is used to treat neck, back and myofascial pain. Cyclobenzaprine functions as a nerve impulse inhibitor.

应用

Cyclobenzaprine hydrochloride has been used to study its effects on the muscles of dystrophin-deficient mdx5Cv mice.
Cyclobenzaprine hydrochloride has been used to study its effect on the muscles of dystrophin-deficient mdx5Cv mice.

生化/生理作用

Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT₂ serotonin receptor antagonist.
Cyclobenzaprine hydrochloride is a type of tricyclic skeletal drug, which is commonly used as a muscle relaxant. It is very effective in treating intractable pain of cervical and lumbar origin caused by skeletal muscle spasm. cyclobenzaprine hydrochloride inhibit tonic α-mononeuronal excitation mediated by descending serotonergic systems by interacting with serotonin receptors at the spinal cord level.

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C₂₀H₂₁N · HCl
分子量	311.85
EC 号	228-264-4
MDL编号	MFCD00079039
PubChem化学物质编号	24278315
NACRES	NA.77

产品性质

质量水平	200
创始人	Johnson & Johnson
SMILES string	Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13
InChI	1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H
InChI key	VXEAYBOGHINOKW-UHFFFAOYSA-N
Gene Information	human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H312 + H332
预防措施声明	P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P312
危险分类	Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Faceshields, Gloves

C3200000

Cyclobenzaprine Hydrochloride

European Pharmacopoeia (EP) Reference Standard

1277.32元/ ;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT₂ serotonin receptor antagonist.

包装

Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₀H₂₁N · HCl
分子量	311.85
MDL编号	MFCD00079039
PubChem化学物质编号	329775025
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
SMILES string	Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13
InChI	1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H
InChI key	VXEAYBOGHINOKW-UHFFFAOYSA-N
Gene Information	human ... HTR2A(3356), HTR2C(3358)

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H312 + H332
预防措施声明	P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P312
危险分类	Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

PHR2797

Supelco

Cyclobenzaprine Hydrochloride

certified reference material, pharmaceutical secondary standard

2107.71元/400 MG;

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产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

生化/生理作用

Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT₂ serotonin receptor antagonist.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

基本信息

经验(实验)分子式	C₂₀H₂₁N · HCl
分子量	311.85
MDL编号	MFCD00079039

产品性质

等级	certified reference material pharmaceutical secondary standard
描述	Pharmaceutical Secondary Standard; Certified Reference Material
形式	solid
包装	pkg of 400 mg
药典可追溯性	traceable to BP BP886 traceable to PhEur C3200000 traceable to USP 1154503
储存温度	2-30℃
SMILES string	Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13
InChI	1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H
InChI key	VXEAYBOGHINOKW-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H312 + H332
预防措施声明	P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312
危险分类	Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

1154503

USP

Cyclobenzaprine Hydrochloride

United States Pharmacopeia (USP) Reference Standard

3231.47元/200 MG;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT₂ serotonin receptor antagonist.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₀H₂₁N · HCl
分子量	311.85
MDL编号	MFCD00079039
NACRES	NA.24

产品性质

manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
SMILES string	Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13
InChI	1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H
InChI key	VXEAYBOGHINOKW-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H312 + H332
预防措施声明	P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P312
危险分类	Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

BP886

Cyclobenzaprine Hydrochloride

British Pharmacopoeia (BP) Reference Standard

1916.08元/25 MG;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT₂ serotonin receptor antagonist.

包装

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₀H₂₁N · HCl
分子量	311.85
MDL编号	MFCD00079039

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	BP
格式	neat
储存温度	2-8℃
SMILES string	Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13
InChI	1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H
InChI key	VXEAYBOGHINOKW-UHFFFAOYSA-N
Gene Information	human ... HTR2A(3356), HTR2C(3358)

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H312 + H332
预防措施声明	P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P312
危险分类	Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable