| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |
| C811190 | MACKLIN | 顺式-4-羟基-L-脯氨酸 | 98% | 30元/50mg; 42元/250mg; 70元/1g; 127元/5g; 592元/25g; | 咨询 |
储存：2~8℃ 状态：白色到灰白色固体 折射率：-59 ° (C=2, H2O) |
| H1169 | TCI | cis-4-Hydroxy-L-proline | >97.0%(T) | 380元/100MG; 1990元/1G; | 咨询 |
基本信息 | 纯度/分析方法 | >97.0%(T) | | 分子式/分子量 | C5H9NO3 = 131.13 | | 外观与形状(20℃) | 固体 | | 储存在惰性气体下 | 存放于惰性气体之中 | | 应避免的情况 | 空气 | | Reaxys-RN | 81440 | | PubChem物质ID | 87558124 | | Merck Index (14) | 4840 |
技术规格 | Appearance | White to Light yellow powder to crystaline | | Purity(Nonaqueous Titration) | min. 97.0 % | | Specific rotation [a]20/D | -56.0 to -60.0 deg(C=2, H2O) |
物性(参考值) | 熔点 | 241 ℃ | | 比旋光度 [α]D | -59° (C=2,H2O) | | 水溶性 | 可溶 |
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| 176032 | J&K | cis-4-Hydroxy-L-proline | 98% | 529元/250MG; 1323元/1G; | 咨询 |
基本信息 | 分子式 | C5H9NO3 | | 分子量 | 131.13 | | 熔点 | 257 | | MDL编码 | MFCD00064319 | | Beilstein | 81440 | | Merck | 4840 | | EINECS 编号 | 210-542-1 |
安全信息 | 提示语 | Danger | | 防范说明 | P262 | | WGK | 3 | | TSCA | 是 |
|
| H27194 | Alfa Aesar | cis-4-Hydroxy-L-proline | 99% | 3162元/250mg; 9495元/1g; | 咨询 |
应用
cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs. 备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents. 基本信息 MDL
MFCD00064319 EINECS
210-542-1 分子式
C5H9NO3 分子量
131.13 熔点
ca 250° dec. 灵敏度
Ambient temperatures. 形态
Powder 溶解性
Soluble in water. 安全信息 TSCA
是 |
| H1637 | Sigma-Aldrich | cis-4-Hydroxy-L-proline | collagen synthesis inhibitor | 748.66元/50 MG; 2645.53元/250 MG; 8777.43元/1 G; | 咨询 |
产品说明 应用 顺式-4-羟基-L-脯氨酸(CHP)是一种可抑制胶原蛋白的合成并已被用作抗癌化合物的脯氨酸类似物。CHP阻断了C2C12鼠骨骼肌细胞中肌管的形成和肌节肌球蛋白重链的表达。CHP抑制了鼠Panc02胰腺癌细胞系和大鼠胰腺癌细胞DSL6A的增殖。 生化/生理作用 顺式-4-羟基-L-脯氨酸(CHP)及其衍生物可能具有抗癌活性。顺式-4-羟基-L-脯氨酸和其他羟基-L-脯氨酸是潜在药物手性合成的重要中间体。 其他说明 鹅膏肽毒素而非如胶原蛋白等动物蛋白的组成成分。 基本信息 | 经验(实验)分子式 | C5H9NO3 | | 分子量 | 131.13 | | Beilstein | 81440 | | EC 号 | 210-542-1 | | MDL编号 | MFCD00064319 | | eCl@ss | 32160406 | | PubChem化学物质编号 | 24895470 | | NACRES | NA.26 |
产品性质 | 质量水平 | 100 | | 测定 | ≥98% (TLC) | | 形式 | powder | | technique(s) | ligand binding assay: suitable | | 颜色 | white to faint yellow | | mp | 257 ℃ (dec.) (lit.) | | application(s) | peptide synthesis | | SMILES string | O[C@@H]1CN[C@@H](C1)C(O)=O | | InChI | 1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1 | | InChI key | PMMYEEVYMWASQN-IMJSIDKUSA-N |
安全信息 | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
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| 967950 | Amethyst | cis-4-Hydroxy-L-proline | 98%, 用于生化 | 40元/50MG; 96元/250MG; 214元/1G; 654元/5G; | 咨询 |
基本信息 | 分子式 | C5H9NO3 | | 分子量 | 131.13 | | 熔点 | 257 | | MDL编码 | MFCD00064319 | | Beilstein | 81440 | | Merck | 4840 | | EINECS 编号 | 210-542-1 |
安全信息 | 提示语 | Danger | | 防范说明 | P262 | | WGK | 3 | | TSCA | 是 |
|
| 208781 | Fluorochem | (2S,4S)-4-Hydroxypyrrolidine-2-carboxylic Acid | 98% | 1078元/1g; 3454元/5g; 5588元/10g; 11176元/25g; | 咨询 |
基本信息 | CAS Number | 618-27-9 | | MDL Number | MFCD00064319 | | Melting Point | 257℃ |
安全信息 | 图形或危害标志 |  | | 危险性说明 | H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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