| CAS: | 61-75-6 | ||||||||||||||||||||
| 分子式: | C18H24BrNO3S | ||||||||||||||||||||
| 分子量: | 414.37 | ||||||||||||||||||||
| 熔点: | 97-99°C | ||||||||||||||||||||
| 中文名称: |
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| 英文名称: |
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| 性质描述: | 白色结晶性粉末。熔点97-99℃。极易溶于水、醇、丙酮,不溶于苯、醚、乙酸乙酯、己烷。 | ||||||||||||||||||||
| 生产方法: | 以邻甲苯胺为原料,经重氮化脱氮并用溴置换生成邻溴甲苯,在光照下和溴素溴化生成邻溴苄基溴甲烷,再用二甲胺在压力下胺化得邻溴苄基二甲胺,最后与对-甲基磺酸乙酯加成得成品。 | ||||||||||||||||||||
| 用途: | 该品为一种肾上腺素阻滞剂。以提高心室致颤阈,故可防治心室颤动,并能直接加强心肌收缩力,改善房室传导作用,用于各种病因所致的室性心律失常,如频发性早搏、阵发性室性心动过速、心室扑动和颤动,尤其对锑剂所致阿-斯氏综合症效果较好。此外,对由于电解质紊乱、酸碱失去平衡或由于洋地黄、奎尼丁等药物中毒所引起的心律失常,也有一定的疗效。为抗心律失常的较好药物。该品有毒。小鼠口服LD50400mg/kg;大鼠肌内注射LD50为250mg/kg。对 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||||||||||
| B849139 | MACKLIN | 托西溴苄铵 | 98% | 303元/5mg; 516元/10mg; 1234元/50mg; 3069元/250mg; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||
储存:室温,干燥 | |||||||||||||||||||||||||||||||||||||||||||||||||
| 1076352 | USP | Bretylium tosylate | United States Pharmacopeia (USP) Reference Standard | 3572.92元/200 MG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. 生化/生理作用 Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade; class III antiarrhythmic agent; competitive inhibitor of acetylcholinesterase. 分析说明 These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. 其他说明 Sales restrictions may apply. 基本信息
产品性质
安全信息
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