[登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 资料中心 > 化工字典 > 61-68-7
关键词:       仅模糊查询
CAS: 61-68-7
分子式: C15H15NO2
分子量: 241.28
中文名称: 
N-(2,3-二甲苯基)-邻氨基苯甲酸
甲灭酸
抗炎止痛灵
甲芬那酸
扑湿痛
英文名称: 
ci-473
cn-35355
coslan
inf 3355
lysalgo
mefenamic acid
mefenaminsaeure
mephenamic acid
mephenaminic acid
methenamic acid
n-(2,3-dimethylphenyl)anthranilic acid
n-(2,3-xylyl)-2-aminobenzoic acid
n-(2,3-xylyl)anthranilic acid
namphen
parkemed
ponalar
ponstan
ponstan forte
ponstel
ponstil
ponstyl
pontal
tanston
vialidon
n-(2,3-xylyl)-anthranilic aci
2-((2,3-dimethylphenyl)amino)benzoic acid
2',3'-dimethyl-2-diphenylaminecarboxylic aci
ac. mefenamico
acide mefenamique
n-2,3-xylyl-anthranilic aci
bafhameritin-m
2-((2,3-dimethyl(phenyl)amino)-benzoic aci
2-((2,3-dimethylphenyl)amino)-benzoic aci
bonabol
展开更多英文名
用途: 用于甾体抗炎镇痛药，适用于关节痛、头痛、脚痛、牙病以及其它炎症性疼痛。
推荐供应商
货号品牌产品名称规格包装、参考价格
M795712MACKLIN甲灭酸10mM in DMSO520元/1ml;   咨询
储存：-20°C
M1782TCIMefenamic Acid>98.0%(T)275元/25G;   540元/100G;   1310元/500G;   咨询

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C15H15NO2 = 241.29
外观与形状(20℃)固体
Reaxys-RN2216243
PubChem物质ID87558870
SDBS (AIST Spectral DB)51771
Merck Index (14)5798
MDL编号MFCD00051721

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(Neutralization titration)min. 98.0 %

物性(参考值)

熔点230 ℃

安全信息

图形或危害标志
信号词危险
危险性说明H302 : 吞咽有害。
H361 : 怀疑对生育能力或胎儿造成伤害。
H362 : 可能对母乳喂养的儿童造成伤害。
H371 : 可能损害器官。
H370 : 会损害器官。
H372 : 长期或反复接触会对器官造成损害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P263 : 怀孕/ 哺乳期间避免接触。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P308+P311 : 如接触到或有疑虑：呼叫急救中心/医生。
P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#CB4550000
585483J&KMefenamic Acid98%, 一种非甾体抗炎剂, 为竞争性的hCOX-1和hCOX-2抑制剂, IC50值分别为40 nM和3 μM237元/25G;   560元/100G;   1377元/500G;   咨询

基本信息

分子式C15H15NO2
分子量241.29
MDL编码MFCD00051721
存储条件Freezer -20℃

产品描述

Mefenamic Acid是一种竞争性COX-1和COX-2抑制剂。

靶点（IC50 & Targe）

COX-1

COX-2

安全信息

图形或危害标志
提示语Warning
危险说明H302
H410
防范说明P264
P270
P301+P312
P330
P501
UN号码3011
危险分类6.1
次要危险性3
包装等级III
M0252600Mefenamic AcidEuropean Pharmacopoeia (EP) Reference Standard1259.15元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

一种 NSAID。避免 MRP 介导的多药耐药。特异性显著增强了蒽环类药物(多柔比星、柔红霉素和表阿霉素)以及替尼泊苷、VP-16 和长春新碱的细胞毒性。

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C15H15NO2
分子量241.29
MDL编号MFCD00051721
PubChem化学物质编号329817763
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCc1cccc(Nc2ccccc2C(O)=O)c1C
InChI1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
InChI keyHYYBABOKPJLUIN-UHFFFAOYSA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
M4267Sigma-AldrichMefenamic Acid750.18元/50 G;   3585.3元/500 G;   咨询

产品说明

应用

甲芬那酸已被用于：

  • 测试其在转基因斑马鱼细胞系(LiPan)中的肝脏毒性作用
  • 测试其在斑马鱼胚胎/幼体中的神经保护功能
  • 在水凝胶微珠中制备粘膜粘附微粒。


一种 NSAID。避免 MRP 介导的多药耐药。特异性显著增强了蒽环类药物(多柔比星、柔红霉素和表阿霉素)以及替尼泊苷、VP-16 和长春新碱的细胞毒性。

包装

50, 500 g in glass bottle

生化/生理作用

甲芬那酸是一种止痛消炎药。它可作为环氧合酶(COX)的抑制剂。它具有肝毒性，并与肝损伤有关。相反，甲芬那酸通过抑制谷氨酸盐诱导的细胞毒性，在体内缺血性中风模型中引起神经保护作用。由于对前列腺素合成的抑制作用，甲草胺可用于减轻水肿和疼痛。

特点和优势

该化合物由 Shionogi 开发。如需浏览其他制药公司开发的化合物和批准的药物/候选药物列表，请点击此处。
这种化合物是 ADME 毒性研究的特色产品。点击此处发现更多特色 ADME 毒性产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
该化合物在受体分类和信号转导手册中多巴胺和去甲肾上腺素代谢页面中进行了详细介绍。如需浏览其他手册页，请点击此处。

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF ( M4267.pdf)中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息，请访问sigma.com/metlin。

基本信息

经验(实验)分子式C15H15NO2
分子量241.29
EC 号200-513-1
MDL编号MFCD00051721
PubChem化学物质编号24896815
NACRESNA.77

产品性质

质量水平100
创始人Shionogi
SMILES stringCc1cccc(Nc2ccccc2C(O)=O)c1C
InChI1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
InChI keyHYYBABOKPJLUIN-UHFFFAOYSA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
92574SupelcoMefenamic Acidanalytical standard764.57元/250 MG;   咨询

产品说明

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
一种 NSAID。避免 MRP 介导的多药耐药。特异性显著增强了蒽环类药物(多柔比星、柔红霉素和表阿霉素)以及替尼泊苷、VP-16 和长春新碱的细胞毒性。

基本信息

经验(实验)分子式C15H15NO2
分子量241.29
EC 号200-513-1
MDL编号MFCD00051721
PubChem化学物质编号329770141

产品性质

质量水平100
等级analytical standard
测定≥98.5% (HPLC)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
杂质≤1.0% water
application(s)forensics and toxicology
pharmaceutical (small molecule)
veterinary
格式neat
SMILES stringCc1cccc(Nc2ccccc2C(O)=O)c1C
InChI1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
InChI keyHYYBABOKPJLUIN-UHFFFAOYSA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1379605USPMefenamic AcidUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Ph

应用

一种 NSAID。避免 MRP 介导的多药耐药。特异性显著增强了蒽环类药物(多柔比星、柔红霉素和表阿霉素)以及替尼泊苷、VP-16 和长春新碱的细胞毒性。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C15H15NO2
分子量241.29
MDL编号MFCD00051721
PubChem化学物质编号329750345
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCc1cccc(Nc2ccccc2C(O)=O)c1C
InChI1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
InChI keyHYYBABOKPJLUIN-UHFFFAOYSA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
079420Fluorochem2-((2,3-Dimethylphenyl)amino)benzoic acid95%220元/1g;   264元/25g;   792元/100g;   咨询

基本信息

CAS Number61-68-7
MDL NumberMFCD00051721
Melting Point230℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
H362: May cause harm to breast-fed children.
H370: Causes damage to organs blood digestive tract.
H371: May cause damage to organs Nervous system.
H372: Causes damage to organs Blood Digestive Tract Kidney.
H361fd: Reproductive toxicity
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P263: Avoid contact during pregnancy/while nursing.
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P307: IF exposed: .
P307 + P311: IF exposed: Call a POISON CENTER or doctor/physician.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P309: IF exposed or if you feel unwell: .
P309 + P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P311: Call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P314: Get medical advice/attention if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9