CAS 606-59-7; cinnabarinic acid

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CAS:

606-59-7

分子式:

C₁₄H₈N₂O₆

分子量:

300.3

英文名称:

cinnabarinic acid

用途:

Cinnabarinic acid is a specific orthosteric agonist of mGlu4 by interacting with residues of the glutamate binding pocket of mGlu4, has no activity at other mGlu receptors.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

C911437

MACKLIN

朱砂精酸

98%

2568元/10mg;

咨询

储存：-20°C，密闭，干燥
状态：红色到非常暗红色粉末

SML0096

Sigma-Aldrich

Cinnabarinic Acid

≥98% (HPLC)

1698.93元/5 MG; 5169.77元/25 MG;

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产品说明

应用

Cinnabarinic acid may be used in studies of the functions of components of the kynurenine metabolic pathway. It may be used to study it role as a metabotropic glutamate receptor (mGlu4R-specific) agonist.

包装

5, 25 mg in glass bottle

生化/生理作用

Cinnabarinic acid is a kynurenine pathway metabolite of tryptophan, produced by the oxidation of 3-Hydroxyanthranilic acid. Cinnabarinic acid leads to loss of mitochondrial respiration and apoptosis, and has also been shown to be an mGlu4R-specific agonist.
Caspase Inducer; mGlu4R agonist
Cinnabarinic acid (CA) connects between initiation of the kynurenine pathway and immune tolerance that is used to prevent neuroinflammation.

特点和优势

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式	C₁₄H₈N₂O₆
分子量	300.22
MDL编号	MFCD18379297
PubChem化学物质编号	329825154
NACRES	NA.25

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	red to very dark red
溶解性	DMSO: ≥4 mg/mL
储存温度	2-8℃
SMILES string	NC1=C(C(O)=O)C2=Nc3c(OC2=CC1=O)cccc3C(O)=O
InChI	1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)
InChI key	FSBKJYLVDRVPTK-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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