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CAS: 6051-87-2
分子式: C19H12O2
分子量: 272.30
熔点: 162-164℃
中文名称: 
β-萘黄酮
β-萘基黄酮
萘黄酮
英文名称: 
3-Phenyl-benzo[f]chromen-1-one
3-Phenyl-1H-naphtho[2,1-b]pyran-1-one
1H-Naphtho[2,1-b]pyran-1-one,3-phenyl-
β-Naphthoflavone
β-Naphthoflavon
5,6-Benzoflavone
5,6-Benzoflavon
1-b)pyran-1-one, 3-phenyl-1h-naphtho(
3-phenyl-1h-naphtho(2,1-b)pyran-1-one
beta-naphthoflavone
beta-nf
展开更多英文名
用途: 类固醇类
推荐供应商
货号品牌产品名称规格包装、参考价格
N865991MACKLINβ-萘黄酮≥99%75元/200mg;   201元/1g;   784元/5g;   2787元/25g;   7500元/100g;   咨询
储存:室温
状态:白色到非常淡黄色到淡黄色棕色晶体或粉末
N0518TCIβ-Naphthoflavone>99.0%(GC)290元/1G;   795元/5G;   咨询

基本信息

纯度/分析方法>99.0%(GC)
分子式/分子量C19H12O2 = 272.30
外观与形状(20℃)固体
Reaxys-RN18991
PubChem物质ID87573843
SDBS (AIST Spectral DB)13540
MDL编号MFCD00004986

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 99.0 %
Melting point162.0 to 166.0 ℃

物性(参考值)

熔点165 ℃

相关法规

RTECS#QL6200000
A18543Alfa Aesarbeta-Naphthoflavone98+%776元/1g;   3523元/5g;   咨询

应用
Inhibitor of aryl hydrocarbon hydroxylase

基本信息

MDL
MFCD00004986

EINECS
227-958-4

分子式
C19H12O2

分子量
272.31

熔点
162-166°

灵敏度
Ambient temperatures.

形态
Crystalline powder

Beilstein
18991

安全信息

RTECS
QL6200000

TSCA

C12817Alfa Aesarbeta-Naphthoflavone99+%756元/1g;   2141元/5g;   咨询

基本信息

Ref#
12817

MDL
4986

分子式
C19 H12 O2

分子量
272.29

N3633Sigma-Aldrichβ-Naphthoflavone≥98%415.37元/1 G;   1291.83元/5 G;   咨询

产品说明

一般描述

β-萘黄酮是一种多环芳烃。

应用

β-萘黄酮已用于:

  • 作为芳烃受体激动剂,阐明其对转基因细胞色素 P450 1A1(cyp1a)报告基因的斑马鱼胚胎中 Cyp1A1 表达的影响
  • 作为 AhR 激动剂,处理原代正常人表皮角质形成细胞(NHEKs),通过蛋白质印迹法研究芳香烃受体(AhR)激活
  • 确定其对肌营养不良蛋白(Dp)71 表达的影响
  • 刺激 Cre 重组酶的表达,并删除侧翼为 loxP 序列的等位基因

包装

1, 5 g in poly bottle

生化/生理作用

β-萘黄酮是人体中芳烃受体(AhR)的外源配体。它是 I 期解毒酶(CYP)和 II 期酶(UDP-GTs)和 NAD(P)H 依赖性醌氧还原酶-1(NQO1)的诱导物。它还诱导细胞色素 P450(Cyp1a)的表达。BNF 通过改变转录因子的结合来抑制 Duchenne 肌营养不良基因(肌营养不良蛋白(Dp)71) 的表达。

基本信息

经验(实验)分子式C19H12O2
分子量272.30
Beilstein18991
EC 号227-958-4
MDL编号MFCD00004986
PubChem化学物质编号57654450
NACRESNA.22

产品性质

质量水平200
测定≥98%
颜色 off-white to yellow
mp164-166 ℃ (lit.)
储存温度2-8℃
SMILES stringO=C1C=C(Oc2ccc3ccccc3c12)c4ccccc4
InChI1S/C19H12O2/c20-16-12-18(14-7-2-1-3-8-14)21-17-11-10-13-6-4-5-9-15(13)19(16)17/h1-12H
InChI keyOUGIDAPQYNCXRA-UHFFFAOYSA-N
Gene Informationrat ... Gabra2(29706)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
493719Fluorochembeta-Naphthoflavone= 99%418元/1g;   1188元/5g;   22418元/100g;   咨询

基本信息

CAS Number6051-87-2
MDL NumberMFCD00004986
Melting Point165℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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