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CAS: 60-56-0
分子式: C4H6N2S
分子量: 114.17
沸点: 180℃
熔点: 143-146℃
中文名称: 
1-甲基-2-咪唑硫醇
2-巯基-1-甲基咪唑
他巴唑
甲硫噻唑
甲硫咪唑
1,3-二氢-1-甲基-2H-咪唑-2-硫酮
甲巯咪唑
英文名称: 
2H-Imidazole-2-thione,1,3-dihydro-1-methyl-
1-Methyl-2-imidazolethiol
1,3-Dihydro-1-methyl-2H-imidazole-2-thione
1,3-dihydro-1-methyl-2H-Imidazole-2-thione
1-methyl-imidazole-2-thio
1-methyl-2-mercaptoimidazole
1-methylimidazole-2-thiol
1-metylo 2 merkaptoimidazolem
2-mercapto-1-methylimidazole
1,3-dihydro-1-methyl-2h-imidazole-2-thion
basolan
danantizol
favistan
frentirox
1-methyl-2-mercapto-imidazol
mercaptazole
mercasolyl
mercazole
mercazolyl
merkazolil
metazolo
methiamazole
methimazol
methimazole
methylmercaptoimidazole
metizol
metothyrin
metothyrine
metotirin
n-methyl-2-mercaptoimidazole
strumazol
strumazole
tapazole
thacapzol
thiamazol
thiamazole
thycapzol
thymidazol
thymidazole
usaf el-30
展开更多英文名
性质描述: 叶片状结晶(乙醇),熔点 146-148℃ ,沸点 280℃ (分解),易溶于水,溶于乙醇、氯仿,微溶于乙醚、苯。
生产方法: 以氨基乙醛缩二乙醇与异硫氰酸甲酯反应制取。亦可从硫氰酸与N-取代的氨基乙缩醛反应制取。亦可从硫氰酸与N-取代的氨基乙缩醛反应制取。
用途: 甲亢平的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
M813240MACKLIN2-巯基-1-甲基咪唑98%30元/5g;   79元/25g;   298元/100g;   1468元/500g;   展开
储存:2~8°C,密封
状态:白色到浅黄色粉末或晶体
M797858MACKLIN2-巯基-1-甲基咪唑10mM in DMSO469元/1ml;   展开
储存:-20°C
M0868TCI2-Mercapto-1-methylimidazole>98.0%(T)(HPLC)480元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C4H6N2S = 114.17
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气
Reaxys-RN742273
PubChem物质ID87572861
SDBS (AIST Spectral DB)15500
Merck Index (14)5971
MDL编号MFCD00179321

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Melting point144.0 to 148.0 ℃

物性(参考值)

熔点145 ℃
水溶性完全溶解
溶解性(可溶于)氯仿,醇
溶解性(微溶于)
溶解度(极微溶)乙醚

安全信息

图形或危害标志
信号词警告
危险性说明H303 : 吞咽可能有害。
H361 : 怀疑对生育能力或胎儿造成伤害。
H317 : 可能造成皮肤过敏反应。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P272 : 受沾染的工作服不得带出工作场地。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P312 : 如感觉不适,呼叫急救中心/医生。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P333 + P313 : 如发生皮肤刺激或皮疹:求医/就诊。
P405 : 存放处须加锁。

相关法规

RTECS#NI8615000
273552J&K2-Mercapto-1-methylimidazole98%402元/25G;   1284元/100G;   5185元/500G;   展开

基本信息

分子式C4H6N2S
分子量114.17
熔点144-147
MDL编码MFCD00179321
Beilstein108646
Merck14,5971
EINECS 编号200-482-4

安全信息

图形或危害标志
提示语Warning
危险说明H317
H361
防范说明P280
WGK3
RTECSNI8615000
TSCA
A13094Alfa Aesar2-Mercapto-1-methylimidazole98%819元/25g;   2564元/100g;   展开

应用
Possesses antioxidant properties

基本信息

MDL
MFCD00179321

EINECS
200-482-4

分子式
C4H6N2S

分子量
114.17

熔点
144-147°

沸点
280° dec.

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Freely soluble in water. Soluble in alcohol, chloroform. Sparingly soluble in ether, benzene.

Beilstein
108646

Merck
14,5971

GHS危害和防范说明

GHS符号

Hazard Statements
H303-H317-H361
May be harmful if swallowed.May cause an allergic skin reaction.Suspected of damaging fertility or the unborn child.

Precautionary Statements
P201-P261-P280-P308+P313-P405-P501a
Obtain special instructions before use.Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF exposed or concerned: Get medical advice/attention.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
9

包装组
III

危险类别
43-63
May cause sensitization by skin contact.Possible risk of harm to the unborn child.

安全等级
24-37-60
Avoid contact with skin.Avoid contact with skin.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
NI8615000

TSCA

Y0000336ThiamazoleEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 30 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C4H6N2S
分子量114.17
Beilstein108646
MDL编号MFCD00179321
PubChem化学物质编号329830910
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp144-147 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCN1C=CNC1=S
InChI1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI keyPMRYVIKBURPHAH-UHFFFAOYSA-N
Gene Informationhuman ... TPO(7173)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H317 - H319 - H361fd
预防措施声明P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
46429SupelcoMethimazoleVETRANAL®, analytical standard641.79元/250 MG;   展开

产品说明

一般描述

甲硫咪唑是一种甲状腺激素抑制剂和一种抗激素药,广泛用于甲亢治疗药物。

应用

甲巯咪唑可作为混合模式固相萃取-反相高效液相色谱-紫外检测法(MMSPE-RP-HPLC-UV)测定鱼匀浆中分析物的参考标准品。
有关合适的仪器技术的更多信息,请参阅产品的分析证书。想要获得更多支持,请联系技术服务部。

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C4H6N2S
分子量114.17
Beilstein108646
EC 号200-482-4
MDL编号MFCD00179321
PubChem化学物质编号329757178
NACRESNA.24

产品性质

质量水平200
等级analytical standard
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp144-147 ℃ (lit.)
application(s)cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
格式neat
SMILES stringCN1C=CNC1=S
InChI1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI keyPMRYVIKBURPHAH-UHFFFAOYSA-N
Gene Informationhuman ... TPO(7173)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H317 - H319 - H361fd
预防措施声明P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
1411005USPMethimazoleUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C4H6N2S
分子量114.17
Beilstein108646
MDL编号MFCD00179321
PubChem化学物质编号329750399

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp144-147 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCN1C=CNC1=S
InChI1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI keyPMRYVIKBURPHAH-UHFFFAOYSA-N
Gene Informationhuman ... TPO(7173)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H317 - H319 - H361fd
预防措施声明P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
301507Sigma-Aldrich2-Mercapto-1-methylimidazole≥99%792.57元/5 G;   1420.42元/25 G;   展开

产品说明

一般描述

研究报道了基于Au-Ag-Au双壳纳米颗粒的局部表面等离子体共振和表面增强拉曼散射生物传感器对2-巯基-1-甲基咪唑的敏感检测。

应用

以 2-巯基-1-甲基咪唑作为疏水电荷诱导色谱配体,进行抗体纯化。它也被用于制备腈功能化的甲巯咪唑基室温离子液体。

包装

5, 25 g in glass bottle

基本信息

经验(实验)分子式C4H6N2S
分子量114.17
Beilstein108646
EC 号200-482-4
MDL编号MFCD00179321
PubChem化学物质编号24858194
NACRESNA.22

产品性质

测定≥99%
mp144-147 ℃ (lit.)
SMILES stringCN1C=CNC1=S
InChI1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI keyPMRYVIKBURPHAH-UHFFFAOYSA-N
Gene Informationhuman ... CYP1A2(1544), TPO(7173)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H317 - H319 - H361fd
预防措施声明P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
M8506SupelcoMethimazoleanalytical standard929.23元/25 G;   2802.08元/100 G;   展开

产品说明

一般描述

甲硫咪唑是一种抗甲状腺剂,广泛用于甲亢治疗。

应用

关于适当的仪器技术的更多信息,请参见产品的检验报告。联系技术服务部寻求进一步支持。
甲硫咪唑可用作不同色谱技术定量测定生物样品中分析物的分析参考标准品。
用于模拟实验动物的甲状腺功能减退症。

包装

25, 100 g in glass bottle

生化/生理作用

甲巯咪唑为硫脲抗甲状腺剂,可阻止碘有机化,从而抑制甲状腺素的合成。

基本信息

经验(实验)分子式C4H6N2S
分子量114.17
Beilstein108646
EC 号200-482-4
MDL编号MFCD00179321
eCl@ss39161002
PubChem化学物质编号329818061
NACRESNA.24

产品性质

等级analytical standard
质量水平200
测定≥99%
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp144-147 ℃ (lit.)
application(s)cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary
格式neat
SMILES stringCN1C=CNC1=S
InChI1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI keyPMRYVIKBURPHAH-UHFFFAOYSA-N
Gene Informationhuman ... TPO(7173)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H317 - H319 - H361fd
预防措施声明P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
PHR3037SupelcoMethimazolepharmaceutical secondary standard, certified reference material2004.1元/500 mg;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

基本信息

经验(实验)分子式C4H6N2S
分子量114.17
Beilstein108646
MDL编号MFCD00179321

产品性质

等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
mp144-147 ℃ (lit.)
application(s)pharmaceutical
药典可追溯性traceable to USP 1411005
储存温度-10 to -25℃
SMILES stringCN1C=CNC1=S
InChI1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI keyPMRYVIKBURPHAH-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H317 - H319 - H361fd
预防措施声明P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
998428Amethyst2-Mercapto-1-methylimidazole98%, 试剂级159元/25G;   492元/100G;   2269元/500G;   展开

基本信息

分子式C4H6N2S
分子量114.17
熔点144-147
MDL编码MFCD00179321
Beilstein108646
Merck14,5971
EINECS 编号200-482-4

安全信息

图形或危害标志
提示语Warning
危险说明H317
H361
防范说明P280
WGK3
RTECSNI8615000
TSCA
322149Fluorochem1-Methyl-1H-imidazole-2(3H)-thione95%330元/5g;   展开

基本信息

CAS Number60-56-0
Melting Point144-147℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H317: May cause an allergic skin reaction.
H319: Causes serious eye irritation.
H361: Suspected of damaging fertility or the unborn child ..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P261: Avoid breathing .
P264: Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear .
P281: Use personal protective equipment as required.
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P333 + P313: If skin irritation or rash occurs: Get medical advice/attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to local regulations..
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