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CAS: 60-27-5
分子式: C4H7N3O
分子量: 113.12
熔点: 255℃
中文名称: 
肌酸酐
2-氨基-1,5-二氢-1-甲基-4H-咪唑啉-4-酮
缩水肌肉素
肌氨基酐
肌酐
2-氨基-1-甲基咪唑啉-4-酮
英文名称: 
2-Amino-1-methyl-2-imidazolin-4-one
2-Imino-1-methylimidazolidin-4-one
1-methylhydantoin-2-imide(creatinine)
Creatinine
2-amino-1,5-dihydro-1-methyl-4H-Imidazol-4-one
Methylglycocyamidine
2-amino-1,5-dihydro-1-methyl-4h-imidazol-4-on
1-Methylglycocyamidine
1-Methylhydantoin-2-imide
2-Imino-1-methyl-4-imidazolidinone
4H-Imidazol-4-one,2-amino-1,5-dihydro-1-methyl-
展开更多英文名
性质描述: 白色结晶。热至300℃分解,溶于水,微溶于醇,几乎不溶于醚、丙酮和氯仿。
生产方法: 将900g水合肌酸、550ml浓盐酸和150ml水加热24h。热滤,滤液在冰浴中冷至0-5℃,加入1L28%氨水。冷却下搅拌,使温度降至0℃,滤出肌酐晶体,用氨水洗涤至不含氯离子,再用冷甲醇洗涤,干燥,得肌酐约550g。
用途: 分析试剂(血液鉴定)、生化研究试剂。
推荐供应商

基本信息

货号品牌产品名称规格包装、参考价格详情
C804987MACKLIN肌酐99%36元/25g;   84元/100g;   330元/500g;   1460元/2.5kg;   展开
储存:2~8°C
状态:白色到淡黄色粉末
C792838MACKLIN肌酐10mM in Water495元/1ml;   展开
储存:-20°C
C0398TCICreatinine>99.0%(T)(HPLC)240元/25G;   630元/100G;   2790元/500G;   展开

基本信息

纯度/分析方法>99.0%(T)(HPLC)
分子式/分子量C4H7N3O = 113.12
外观与形状(20℃)固体
Reaxys-RN112061
PubChem物质ID87565526
SDBS (AIST Spectral DB)1991
Merck Index (14)2569
MDL编号MFCD00059730

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 99.0 area%
Purity(Nonaqueous Titration)min. 99.0 %

物性(参考值)

熔点255 ℃(dec.)
990497J&KCreatinine99%85元/10G;   134元/50G;   534元/250G;   2027元/1KG;   展开

基本信息

分子式C4H7N3O
分子量113.12
熔点295
闪点299
MDL编码MFCD00059730
Beilstein112061
Merck14,2569
EINECS 编号200-466-7

一般描述

Creatinine is a breakdown product formed by the degradation of creatine phosphate from muscles. The kidneys extract creatinine from the body by filtering almost all of it from the blood and excreting it in the urine. Serum creatinine is the most commonly used indicator for renal functioning. In chemical synthesis, creatinine is used as a heterocyclic nitrogenous compound that produces electron-rich and highly basic creatinine derivatives.

应用

A nitrogen donor building block to prepare nitrogen-containing heterocyclic derivatives.A reactant to synthesize donor-acceptor type carbon nitride copolymer, which is used as a photocatalyst in hydrogen production.

A starting material to prepare creatol(2-amino-1,5-dihydro-5-hydroxy methylimidazol-4-one) via creatinine chloramine.A reactant to synthesize 3-substituted-3-hydroxyisatins by gold-catalyzed aldolization with various isatins.

安全信息

防范说明P262
WGK3
TSCA
B23097Alfa AesarCreatinine98%506元/10g;   2030元/50g;   4336元/250g;   展开

应用
Creatinine levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which reflects the glomerular filtration rate (GFR), an important clinical index of renal function. It is a substrate for creatininase.

备注
Store in a cool, dry conditions, in well sealed conditions. Store away from oxidizing agents.

基本信息

MDL
MFCD00059730

EINECS
200-466-7

分子式
C4H7N3O

分子量
113.12

熔点
ca 255° dec.

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water (90 mg/ml at 20°C), alcohol (slightly), and ethanol (slightly). Insoluble in acetone, and chloroform.

Beilstein
112061

Merck
14,2569

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA

C22894Alfa AesarCreatinine99+%834元/25g;   1345元/50g;   4588元/250g;   展开

基本信息

Ref#
22894

MDL
59730

分子式
C4 H7 N3 O

分子量
113.12

闪点
290

形态
White cryst powder

1.05206MilliporeCreatininefor biochemistry633.87元/50 G;   4374.85元/500 G;   展开

产品说明

一般描述

for biochemistry

应用

Creatinine for biochemistry. CAS 60-27-5, pH 7.0 - 9.0 (50 g/l, H₂O, 20 °C).

分析说明

Assay (perchloric acid titration)≥ 99.0 %
Identity (IR-spectrum)passes test
pH-value (5 %; water)7 - 9
Spec. Absorptivity A 1%/1cm (234 nm; 0.001 %; buffer pH 7.0)620 - 640
Chloride (Cl)≤ 0.2 %
Heavy metals (as Pb)≤ 0.001 %
Creatine (HPLC)≤ 0.2 %
分子量113.11
EC索引号200-466-7

产品性质

质量水平100
形式solid
pH值(酸碱度)7.0-9.0 (20 ℃, 50 g/L in H2O)
mp305 ℃ (decomposition)
溶解性 90 g/L
堆积密度484 kg/m3
储存温度no temp limit
InChI1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
InChI keyDDRJAANPRJIHGJ-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)554.0 °F
闪点(C)290 ℃
C4255Sigma-AldrichCreatinineanhydrous, ≥98%292.77元/10 MG;   344.74元/10 G;   617.19元/25 G;   1503.36元/100 G;   8554.82元/1 KG;   展开

产品说明

一般描述

肌酐是在肌肉来源的磷酸肌酸降解过程中产生的分解产物。几乎所有肌酐都由肾脏从血液中滤过并排到尿液中,从而排出体外。血清肌酐是肾功能的最常用指标。在化学合成中,肌酐作为杂环含氮化合物,可产生富电子和强碱性肌酐衍生物。

应用

肌酐可用于:

包装

10, 25, 100 g in poly bottle
10 mg in glass bottle
1 kg in poly bottle

基本信息

经验(实验)分子式C4H7N3O
分子量113.12
Beilstein112061
EC 号200-466-7
MDL编号MFCD00059730
PubChem化学物质编号24892677
NACRESNA.22

产品性质

质量水平200
等级anhydrous
测定≥98%
mp295 ℃ (dec.) (lit.)
SMILES stringCN1CC(=O)N=C1N
InChI1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
InChI keyDDRJAANPRJIHGJ-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)554.0 °F - closed cup
闪点(C)290.00 ℃ - closed cup
个人防护装备Eyeshields, Gloves, type N95 (US)
PHR1462SupelcoCreatininePharmaceutical Secondary Standard; Certified Reference Material1461.17元/1 G;   展开

产品说明

一般描述

用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。肌酐是肌肉中磷酸肌酸代谢过程中产生的副产物。它通过尿液排泄,血清肌酐水平是肾脏健康的最常用指标。

应用

肌酐可用作药物参考标准品,用于通过分光光度法和高效液相色谱测定生物体液中的分析物。
这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

这些二级标准品可追溯至USP、EP和BP一级标准品。

其他说明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

如需查看本品的分析证书示例,请在下框中输入LRAA3010。这只是一个示例证书并可能不是您所收到的批次。

基本信息

经验(实验)分子式C4H7N3O
分子量113.12
Beilstein112061
EC 号200-466-7
MDL编号MFCD00059730
PubChem化学物质编号329823394
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp295 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1150353
储存温度2-30℃
SMILES stringCN1CC(=O)N=C1N
InChI1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
InChI keyDDRJAANPRJIHGJ-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)554.0 °F - closed cup
闪点(C)290.00 ℃ - closed cup
NIST914BCreatinineNIST® SRM® 914b13321.1元/10 G;   展开

产品说明

一般描述

This Standard Reference Material (SRM) is certified as a chemical of known purity. It is intended primarily for use in the calibration and standardization of procedures used for determination of creatinine concentration and for routine evaluations of daily working standards used in these procedures. For more information, please refer to the SDS and COA.
SRM 914B _SDS
SRM 914B_cert

法律信息

NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology

基本信息

经验(实验)分子式C4H7N3O
分子量113.12
Beilstein112061
MDL编号MFCD00059730

产品性质

等级certified reference material
包装pkg of 10 g
manufacturer/tradenameNIST®
mp295 ℃ (dec.) (lit.)
格式neat
SMILES stringCN1CC(=O)N=C1N
InChI1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
InChI keyDDRJAANPRJIHGJ-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)554.0 °F
闪点(C)290 ℃
1150353USPCreatinineUnited States Pharmacopeia (USP) Reference Standard3487.56元/100 MG;   展开

产品说明

一般描述

本品按现行药典规定交付。所有本产品相关的支持信息,包括SDS和任何产品信息宣传册,均是在药典的授权下制定和发布的。
如需进一步信息和支持,请访问现行药典网站。

分析说明

这些产品仅供测试和分析使用。它们不适用于人类或动物的给药,不可用于诊断、治疗或治愈任何疾病。  

其他说明

可能适用相应的销售限制。

基本信息

经验(实验)分子式C4H7N3O
分子量113.12
Beilstein112061
MDL编号MFCD00059730
PubChem化学物质编号329749458
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp295 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCN1CC(=O)N=C1N
InChI1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
InChI keyDDRJAANPRJIHGJ-UHFFFAOYSA-N

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
240558Fluorochem2-Imino-1-methylimidazolidin-4-one95%264元/100g;   展开

基本信息

CAS Number60-27-5
MDL NumberMFCD00059730
Melting Point255℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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