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CAS: 5959-52-4
分子式: C11H9NO2
分子量: 187.20
熔点: 210℃
中文名称: 
3-氨基-2-苯丙酸
3-氨基-2-萘甲酸
英文名称: 
3-amino-2-naphthoic aci
3-amino-2-naphthalenecarboxylic aci
3-amino-2-naphthalenecarboxylic acid
3-amino-2-naphthoic acid
3-aminoisonaphthoic acid
3-Aminonaphthalene-2-carboxylic acid
性质描述: 该品为黄色叶状体晶体。熔点为216-217℃。溶于乙醇和乙醚,微溶于热水,溶液中带绿色荧光。
生产方法: 在有催化剂的条件下,用3-羟基-2-萘甲酸与氨共热制得。将28%的氨水、氯化锌和3-羟基-2-萘甲酸依次加入高压釜中,搅拌,加热3h后使温度达195℃,保持36h,压力在2.7MPa左右。冷至室温,再向反应混合物中加入浓盐酸,将悬浮物煮沸30min,趁热过滤。将滤饼和水、盐酸混合,再煮沸30min,过滤。两次滤液冷却后沉淀出3-氨基-2-萘甲酸盐,过滤。将滤液加热至85℃,加盐,继续冷却,得第二批盐酸盐。再加40%氢氧化钠溶液,使呈碱性,将混合物加热至85℃,加入浓盐酸,直至刚果红试纸呈酸性,搅拌,再加适量10%乙酸钠溶液使刚果红试纸不变蓝。用热水洗涤、压干即得成品。
用途: 有机合成,染料中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
A837970MACKLIN3-氨基-2-萘甲酸technical grade, 80 %86元/1g;   405元/5g;   1450元/25g;   展开
储存:室温,干燥
状态:淡黄色到橄榄绿色固体
A2258TCI3-Amino-2-naphthoic Acid>97.0%(T)415元/1G;   1220元/5G;   展开

基本信息

纯度/分析方法>97.0%(T)
分子式/分子量C11H9NO2 = 187.20
外观与形状(20℃)固体
Reaxys-RN744099
PubChem物质ID87561639
Merck Index (14)452
MDL编号MFCD00004115

技术规格

AppearanceLight yellow to Amber to Dark green powder to crystal
Purity(HPLC)min. 96.0 area%
Purity(Neutralization titration)min. 97.0 %

物性(参考值)

熔点212 ℃(dec.)
溶解性(可溶于)乙醚,醇

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#QL1400000
580836J&K3-Amino-2-naphthoic Acid92%342元/1G;   1056元/5G;   2780元/25G;   展开

基本信息

分子式C11H9NO2
分子量187.19
熔点210
MDL编码MFCD00004115
Beilstein744099
Merck14,452
EINECS 编号227-726-2

安全信息

图形或危害标志
提示语Warning
危险说明H302
防范说明P301+P312
WGK3
RTECSQL1400000
L19312Alfa Aesar3-Amino-2-naphthoic Acid97%1057元/1g;   3516元/5g;   7972元/25g;   展开

应用
3-Amino-2-naphthoic acid is a dyes analytical reagent which is used as an intermediate for organic synthesis.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00004115

EINECS
227-726-2

分子式
C11H9NO2

分子量
187.20

熔点
ca 210° dec.

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in alcohol and ether. Insoluble in water.

Beilstein
744099

Merck
14,452

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
26-36/37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
QL1400000

TSCA

A66804Sigma-Aldrich3-Amino-2-naphthoic Acidtechnical grade, 80%1039.05元/5 G;   展开

基本信息

线性分子式H2NC10H6CO2H
分子量187.19
Beilstein744099
EC 号227-726-2
MDL编号MFCD00004115
PubChem化学物质编号24891127
NACRESNA.22

产品性质

等级technical grade
质量水平200
测定80%
形式powder, crystals or chunks
reaction suitabilityreaction type: solution phase peptide synthesis
颜色 yellow to olive green
mp212-215 ℃ (dec.) (lit.)
application(s)peptide synthesis
SMILES stringNc1cc2ccccc2cc1C(O)=O
InChI1S/C11H9NO2/c12-10-6-8-4-2-1-3-7(8)5-9(10)11(13)14/h1-6H,12H2,(H,13,14)
InChI keyXFXOLBNQYFRSLQ-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
010658Fluorochem3-Amino-2-naphthoic Acid97%1056元/5g;   3388元/25g;   展开

基本信息

CAS Number5959-52-4
MDL NumberMFCD00004115
Melting Point210-213℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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