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CAS: 59263-76-2
分子式: C15H23NO·HCl
分子量: 269.81
英文名称: 
3-(3-ethylhexahydro-1-methyl-1h-azepin-3-yl)-pheno hydrochloride
3-(3-ethylhexahydro-1-methyl-1h-azepin-3-yl)phenol hydrochloride
m-(3-ethyl-1-methyl-hexahydro-1h-azepin-3-yl)phenol hydrochloride
meptazinol hydrochloride
m-(3-ethyl-1-methyl-hexahydro-1h-azepin-3-yl)-pheno hydrochloride
3-(3-ethylhexahydro-1-methyl-1h-azepin-3-yl)-phenohydrochloride
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M2824Sigma-AldrichMeptazinol hydrochloride822.3元/10 MG;   展开

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Meptazinol entered the human pharmaceutical market as a racemic mixture in the 1980s for use as an analgesic. Its pharmacology is not completely understood; however, its analgesic properties are mostly due to its partial agonism at the mu1 opioid receptor. Due to its partial agonism, Meptazinol antagonizes morphine dependence in vivo. Its advantage over other opiates is its reduced capacity to cause addition and respiratory depression, also due to its intrinsic activity as a partial agonist. Meptazinol has been found to have additional activity as an acetylcholinesterase (AChE) inhibitor, particularly in its (-) enantiomeric form, which may partially explain its analgesic properties. AChE inhibitors are used to treat Alzheimer′s disease, providing additional interest in this compound.

特点和优势

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式C15H23NO· HCl
分子量269.81
EC 号261-683-0
MDL编号MFCD00941476
PubChem化学物质编号329817952
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to off-white
溶解性H2O: >10 mg/mL
创始人Wyeth
SMILES stringCl.CCC1(CCCCN(C)C1)c2cccc(O)c2
InChI1S/C15H23NO.ClH/c1-3-15(9-4-5-10-16(2)12-15)13-7-6-8-14(17)11-13;/h6-8,11,17H,3-5,9-10,12H2,1-2H3;1H
InChI keyMPJUSISYVXABBH-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
BP583Meptazinol hydrochlorideBritish Pharmacopoeia (BP) Reference Standard1916.08元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Meptazinol entered the human pharmaceutical market as a racemic mixture in the 1980s for use as an analgesic. Its pharmacology is not completely understood; however, its analgesic properties are mostly due to its partial agonism at the mu1 opioid receptor. Due to its partial agonism, Meptazinol antagonizes morphine dependence in vivo. Its advantage over other opiates is its reduced capacity to cause addition and respiratory depression, also due to its intrinsic activity as a partial agonist. Meptazinol has been found to have additional activity as an acetylcholinesterase (AChE) inhibitor, particularly in its (-) enantiomeric form, which may partially explain its analgesic properties. AChE inhibitors are used to treat Alzheimer′s disease, providing additional interest in this compound.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C15H23NO· HCl
分子量269.81
EC 号261-683-0
MDL编号MFCD00941476

产品性质

等级pharmaceutical primary standard
质量British Pharmacopoeia (BP) Reference Standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringCl.CCC1(CCCCN(C)C1)c2cccc(O)c2
InChI1S/C15H23NO.ClH/c1-3-15(9-4-5-10-16(2)12-15)13-7-6-8-14(17)11-13;/h6-8,11,17H,3-5,9-10,12H2,1-2H3;1H
InChI keyMPJUSISYVXABBH-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 + P330 - P501
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
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