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CAS: 59016-56-7
分子式: C8H10BF4N3
分子量: 234.99
熔点: 196-200°C
英文名称: 
1-Cyano-4-dimethylaminopyridinium tetrafluoroborate
CDAP
1-cyano-4-dimethylaminopyridinium tetra-fluoroborate
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货号品牌产品名称规格包装、参考价格详情
C805990MACKLIN1-氰基-4-二甲氨基吡啶四氟硼酸酯98%61元/100mg;   279元/500mg;   496元/1g;   1846元/5g;   8648元/25g;   展开
储存:-20℃, 密封干燥, 惰性气体保存
状态:白色到黄色粉末或晶体或固体
C2348TCI1-Cyano-4-(dimethylamino)pyridinium Tetrafluoroborate>98.0%(N)715元/100MG;   展开

基本信息

纯度/分析方法>98.0%(N)
分子式/分子量C8H10BF4N3 = 234.99
外观与形状(20℃)固体
储存温度<0℃
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (分解),加热
Reaxys-RN5685616
PubChem物质ID125307503
MDL编号MFCD00011998

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(with Total Nitrogen)min. 98.0 %
Melting point194.0 to 204.0 ℃

物性(参考值)

熔点198 ℃
最大吸收波长301(CH3CN) nm

安全信息

图形或危害标志
信号词危险
危险性说明H302 : 吞咽有害。
H314 : 造成严重皮肤灼伤和眼损伤。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P260 : 不要吸入粉尘或烟雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P303 + P361 + P353 : 如皮肤(或头发)沾染:立即脱掉所有沾污的衣物。用水清洗皮肤/淋浴。
P301 + P330 + P331 : 如误吞咽:漱口。不要诱导呕吐。
P363 : 沾染的衣服清洗后方可重新使用。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P304 + P340 + P310 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。立即呼叫急救中心/医生。
P305 + P351 + P338 + P310 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。
P405 : 存放处须加锁。

运输信息

UN编号UN1759
类别8
包装类别 III
监管条件代码(*)
559768J&K1-Cyano-4-(dimethylamino)pyridinium Tetrafluoroborate98%390元/100MG;   1455元/500MG;   展开

基本信息

分子式C8H10BF4N3
分子量234.99
熔点196-200
MDL编码MFCD00011998
Beilstein5685616
存储条件Freezer -20℃

安全信息

图形或危害标志
提示语Danger
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
TSCA
H59334Alfa Aesar1-Cyano-4-(dimethylamino)pyridinium Tetrafluoroborate98%1539元/100mg;   7067元/500mg;   展开

应用
1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate is a cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity.

备注
Store at room temperature. Keep away from oxidizing agents and heats.

基本信息

MDL
MFCD00011998

分子式
C8H10BF4N3

分子量
234.99

熔点
196-200°

灵敏度
Store at -20°C.

形态
Solid

溶解性
Soluble in water, and acetonitrile.

Beilstein
5685616

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H332-H315-H319-H335
Harmful if swallowed.Harmful if inhaled.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
III

危险类别
20/22-36/37/38
Harmful by inhalation and if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
9-26-36/37-60
Keep container in a well-ventilated place.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

TSCA

RES1458CSAFCCDAP1188.76元/100 mg;   3919.97元/500 mg;   6664.74元/1 g;   展开

产品说明

包装

产品有以下包装规格:
RES1458C-B101X: 100 mg容器
RES1458C-B102X: 500 mg容器
RES1458C-B103X: 1 g容器

基本信息

经验(实验)分子式C8H10BF4N3
分子量234.99
Beilstein5685616
MDL编号MFCD00011998
PubChem化学物质编号329824259
NACRESNA.21

产品性质

储存温度−20℃
SMILES string[F-].FB(F)F.CN(C)c1cc[n+](cc1)C#N
InChI1S/C8H10N3.BF3.FH/c1-10(2)8-3-5-11(7-9)6-4-8;2-1(3)4;/h3-6H,1-2H3;;1H/q+1;;/p-1
InChI keyONCRRSYBEJHQMM-UHFFFAOYSA-M
C2776Sigma-Aldrich1-Cyano-4-dimethylaminopyridinium tetrafluoroborateorganic cyanylating reagent1974.18元/100 MG;   9807.41元/500 MG;   展开

产品说明

应用

用于蛋白质巯基的氰基化试剂; 用于制备蛋白-多糖偶联物。 用于多糖树脂的激活剂以及在保持内毒素活性的同时与脂多糖的偶联。

包装

100, 500 mg in glass bottle

基本信息

经验(实验)分子式C8H10BF4N3
分子量234.99
Beilstein5685616
MDL编号MFCD00011998
PubChem化学物质编号24892528

产品性质

质量水平300
储存温度−20℃
SMILES string[F-].FB(F)F.CN(C)c1cc[n+](cc1)C#N
InChI1S/C8H10N3.BF3.FH/c1-10(2)8-3-5-11(7-9)6-4-8;2-1(3)4;/h3-6H,1-2H3;;1H/q+1;;/p-1
InChI keyONCRRSYBEJHQMM-UHFFFAOYSA-M

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
SBR00023Sigma-Aldrich1-Cyano-4-dimethylaminopyridinium tetrafluoroborate Ready Made Solutionorganic cyanylating reagent, 100 mg/mL in acetonitrile2044.7元/1 ML;   展开

产品说明

应用

Polysaccharide conjugation: CDAP Ready Made Solution (100mg/mL in acetonitrile) should be added in a ratio of 1mg CDAP to 1mg polysaccharide while vortexing (Example: per 1mg polysaccharide add 10μL of CDAP Ready Made Solution). Add 0.2M triethylamine, 10μL per 1mg polysaccharide to raise the pH of the reaction.

生化/生理作用

CDAP is a cyanylation reagent for protein sulfhydryl groups which is used to prepare protein-polysaccharide conjugates. CDAP is also an activating agent for polysaccharide resins and is used for the conjugation of lipopolysaccharides while retaining their endotoxic activity.

CDAP is considered to be a less toxic reagent as compared to cyanogen bromide (CNBr) (a known polysaccharides activator). In addition, CDAP is easier to use as it can be employed at a lower pH and has fewer side reactions. It is known that CDAP polysaccharide activation efficiency is optimal at pH 9-10. It was also reported that direct conjugation of protein to CDAP-activated polysaccharides can be performed under mildly alkaline conditions (pH 7-9). It has also been reported that proteins could also be conjugated to CDAP-activated polysaccharides at pH 5.

基本信息

经验(实验)分子式C8H10BF4N3
分子量234.99

产品性质

生物来源synthetic
测定≥97%
形式liquid
浓度100 mg/mL in acetonitrile
运输dry ice
储存温度−20℃

安全信息

象形图GHS02GHS07
警示用语:Danger
危险声明H225 - H302 + H312 + H332 - H315 - H319
预防措施声明P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
危险分类Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2
储存分类代码3 - Flammable liquids
WGKWGK 3
闪点(F)35.6 °F
闪点(C)2 ℃
062226Fluorochem1-Cyano-4-(dimethylamino)pyridinium Tetrafluoroborate98%1980元/250mg;   2640元/1g;   展开

基本信息

CAS Number59016-56-7
MDL NumberMFCD00011998

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H314: Causes severe skin burns and eye damage.
防范说明 P260: Do not breathe .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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