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CAS: 5891-21-4
分子式: C5H9ClO
分子量: 120.58
沸点: 71-72℃(2
中文名称: 
1-氯戊酮-4
3-乙酰-1-氯丙烷
5-氯-2-戊酮
英文名称: 
5-chloro-2-pentanon
5-chloro-2-pentanone
5-chloro-pentan-2-one
3-acetyl-1-chloropropane
Methyl 3-chloropropyl ketone
3-Chloropropyl Methyl Ketone
性质描述: 液体。沸点76℃(4.53kPa),71-72℃(2.67kPa),相对密度1.0523(20/4℃),折光率1.4375,闪点35℃。溶于苯、乙醇。
生产方法: 由乙酰正丙醇经氯化而得。将盐酸和乙酰正丙醇加入反应锅中加热,蒸出盐酸和5-氯-2-戊酮,冷却后静置分层,下层盐酸返回反应锅,直至无5-氯-2-戊酮蒸出为止。另外一种操作方法是,向盐酸和氯化钠中按比例加入硫酸和乙酰正丙醇,于84-88℃氯化15min即得。
用途: 药物氯喹磷酸盐的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C804934MACKLIN5-氯-2-戊酮96%30元/25g;   48元/100g;   232元/500g;   910元/2.5kg;   展开
储存:2~8°C
状态:无色到棕色澄清液体
C0867TCI5-Chloro-2-pentanone (stabilized with K2CO3)>98.0%(GC)830元/25ML;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C5H9ClO = 120.58
外观与形状(20℃)液体
储存温度0-10℃
储存在惰性气体下存放于惰性气体之中
应避免的情况空气,加热
Reaxys-RN1098490
PubChem物质ID87565926
SDBS (AIST Spectral DB)10178
MDL编号MFCD00001008

技术规格

AppearanceColorless to Brown clear liquid
Purity(GC)min. 98.0 %

物性(参考值)

沸点106 ℃/20 mmHg
闪点35 ℃
比重1.05
折射率1.44

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H226 : 易燃液体和蒸气。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P240 : 容器和装载设备接地/等势联接。
P210 : 远离热源/火花/明火/热表面。禁止吸烟。
P233 : 保持容器密闭。
P243 : 采取防止静电放电的措施。
P241 : 使用防爆的电气/通风/照明设备。
P242 : 只能使用不产生火花的工具。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P370 + P378 : 火灾时:使用干砂、干粉或抗醇泡沫灭火。
P303 + P361 + P353 : 如皮肤(或头发)沾染:立即脱掉所有沾污的衣物。用水清洗皮肤/淋浴。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P403 + P235 : 存放在通风良好的地方。保持低温。

相关法规

RTECS#SA8143500

运输信息

UN编号UN1224
类别3
包装类别 III
监管条件代码(*)
344593J&K5-Chloro-2-pentanone97%104元/25G;   181元/100G;   618元/500G;   展开

基本信息

分子式C5H9ClO
分子量120.58
沸点71-72
闪点35
密度1.057
折光率(n20D)1.4380
MDL编码MFCD00001008
Beilstein1098490
EINECS 编号227-565-8
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H226
H302
H315
H319
H335
防范说明P210
P261
P280
P301+P312
P302+P352
P305+P351+P338
UN号码1224
危险分类3
包装等级III
WGK3
RTECSSA8143500
TSCA
A10269Alfa Aesar5-Chloro-2-pentanone94%484元/25g;   1471元/100g;   6303元/500g;   展开

应用
5-Chloro-2-pentanone used in the preparation of destructible surfactants.

备注
keep container tightly closed. Store in cool, dry conditions in well sealed containers. Store away from strong oxidizing agents

基本信息

MDL
MFCD00001008

EINECS
227-565-8

分子式
C5H9ClO

分子量
120.58

沸点
63-64°/12mm

闪点
35°(95°F)

密度
1.053

折射率
1.4380

灵敏度
Keep Cold.

形态
Liquid

溶解性
Soluble in chloroform and methanol.

Beilstein
1098490

GHS危害和防范说明

GHS符号

Hazard Statements
H226-H302-H315-H319-H335
Flammable liquid and vapour.Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Avoid breathing dust/fume/gas/mist/vapours/spray.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
3

包装组
III

危险类别
10-22-36/37/38
Flammable.Harmful if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

欧盟危险品标志

RTECS
SA8143500

TSCA

C38829Alfa Aesar5-Chloro-2-pentanone90%798元/25g;   2888元/100g;   展开

基本信息

Ref#
38829

MDL
1008

分子式
C5 H9 Cl O

分子量
120.58

闪点
35

密度
1053

安全信息

危险等级
3

包装组
III

C62603Sigma-Aldrich5-Chloro-2-pentanonetechnical grade, 85%416.2元/25 G;   1465.33元/100 G;   展开

基本信息

线性分子式Cl(CH2)3COCH3
分子量120.58
Beilstein1098490
EC 号227-565-8
MDL编号MFCD00001008
PubChem化学物质编号24892849
NACRESNA.22

产品性质

等级technical grade
质量水平100
测定85%
杂质1-2% water
折射率n20/D 1.438 (lit.)
bp71-72 ℃/20 mmHg (lit.)
密度1.057 g/mL at 25 ℃ (lit.)
SMILES stringCC(=O)CCCCl
InChI1S/C5H9ClO/c1-5(7)3-2-4-6/h2-4H2,1H3
InChI keyXVRIEWDDMODMGA-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)152.6 °F - closed cup
闪点(C)67 ℃ - closed cup
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
326218Fluorochem5-Chloropentan-2-one (stabilized with K2CO3)95%220元/1g;   308元/25g;   814元/100g;   1540元/250g;   展开

基本信息

CAS Number5891-21-4
MDL NumberMFCD00001008
Boiling Point71-72℃/20mm
Density1.057

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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