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CAS: 583-68-6
分子式: C7H8BrN
分子量: 186.05
沸点: 240℃
熔点: 14-16℃
中文名称: 
2-溴-4-甲基苯胺
3-溴-4-氨基甲苯
邻溴对硝基苯胺
英文名称: 
4-Amino-3-bromotoluene
2-bromo-p-toluidin
2-bromotoluidine
4-methyl-2-bromoaniline
2-bromo-4-methyl-benzenamin
2-bromo-4-methylaniline
2-Bromo-4-methylbenzenamine
2-Bromo-p-toluidine
Benzenamine,2-bromo-4-methyl-
性质描述: 无色液体。熔点26℃,沸点240℃,相对密度1.500,折光率1.6020。与醇、醚混溶,不溶于水。
生产方法: 将对甲苯胺与冰乙酸加热回流2h转化为N-乙酰对甲苯胺,冷却至45℃,滴加溴,溴化反应控制在50-55℃下进行。将反应物注入亚硫酸钠水溶液中,析出3-溴-4-乙酰氨基甲苯。然后用浓盐酸水解,所得盐酸盐与氢氧化钠溶液作用,即得游离的2-溴-4-甲基苯胺。产率51-57%。
用途: 有机合成中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
B823947MACKLIN2-溴-4-甲基苯胺98%27元/5g;   86元/25g;   288元/100g;   1335元/500g;   展开
储存:2~8℃
状态:棕色液体
B0540TCI2-Bromo-4-methylaniline>98.0%(GC)100元/5G;   390元/25G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C7H8BrN = 186.05
外观与形状(20℃)液体
储存在惰性气体下存放于惰性气体之中
应避免的情况光,空气
Reaxys-RN1931711
PubChem物质ID87563561
SDBS (AIST Spectral DB)10684
MDL编号MFCD00007635

技术规格

AppearanceColorless to Brown clear liquid
Purity(GC)min. 98.0 %
Purity(Nonaqueous Titration)min. 98.0 %

物性(参考值)

熔点17 ℃
沸点240 ℃
比重1.49
折射率1.60

安全信息

图形或危害标志
信号词危险
危险性说明H301 + H311 + H331 : 吞咽、皮肤接触或吸入中毒。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P271 : 只能在室外或通风良好之处使用。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P361 + P364 : 立即脱掉所有沾染的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P302 + P352 + P312 : 如皮肤沾染:用水充分清洗。如感觉不适,呼叫急救中心/医生。
P304 + P340 + P311 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。呼叫急救中心/医生。
P403 + P233 : 存放在通风良好的地方。保持容器密闭。
P405 : 存放处须加锁。

相关法规

RTECS#XU4300000

运输信息

UN编号UN2810
类别6.1
包装类别 III
监管条件代码(*)
134047J&K2-Bromo-4-methylaniline98%267元/10ML;   1030元/50ML;   展开

基本信息

分子式C7H8BrN
分子量186.05
熔点14-16
沸点240
闪点110
密度1.5
折光率(n20D)1.6020
MDL编码MFCD00007635
Beilstein1931711
EINECS 编号209-515-7

安全信息

图形或危害标志
提示语Danger
危险说明H301
H311
H331
防范说明P261
P280
P301+P310
P311
UN号码2810
危险分类6.1
包装等级III
WGK3
RTECSXU4300000
TSCA
A13818Alfa Aesar2-Bromo-4-methylaniline99%615元/10g;   2361元/50g;   10168元/250g;   展开

应用
The N-(3, 5-Dichlorophenyl) naphthaldimine was obtained from the reaction of 2-hy- droxynaphthalene-l-carbaldehyde (0.01 mol) with a solution of 2-bromo-4-methylaniline (0.01 mol) in 40 ml of ethanol. Reaction of 2-bromo-4-methylaniline was quite clean, albeit 3,4-diaminotoluene was isolated just in 37% yield after flash chromatography on silica gel. The bromomethylquinoline starting material 16 was synthesized in two steps using an optimized process route by condensing 2-bromo-4-methylaniline.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

基本信息

MDL
MFCD00007635

EINECS
209-515-7

分子式
C7H8BrN

分子量
186.06

熔点
14-16°

沸点
240-242°

闪点
>110°(230°F)

密度
1.494

折射率
1.6030

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Insoluble in water.

Beilstein
1931711

GHS危害和防范说明

GHS符号

Hazard Statements
H301-H311-H315-H319
Toxic if swallowed.Toxic in contact with skin.Causes skin irritation.Causes serious eye irritation.

Precautionary Statements
P280h-P305+P351+P338-P309-P310-P302+P352
Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.IF ON SKIN: Wash with plenty of soap and water.

安全信息

危险等级
6.1

包装组
III

危险类别
24/25-36/38
Toxic in contact with skin and if swallowed.Irritating to eyes and skin.

安全等级
26-28-36/37-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer).Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

RTECS
XU4300000

TSCA

001127Fluorochem2-Bromo-4-methylaniline97%220元/1g;   286元/25g;   814元/100g;   4070元/500g;   展开

基本信息

CAS Number583-68-6
MDL NumberMFCD00007635
Boiling Point120-122℃/30mm
Melting Point14-16℃
Density1.5

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H311: Toxic in contact with skin.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P322: Specific measures (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P361: Remove/Take off immediately all contaminated clothing.
P362: Take off contaminated clothing and wash before reuse.
P363: Wash contaminated clothing before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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