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CAS: 580-15-4
分子式: C9H8N2
分子量: 144.18
沸点: 192 °C
熔点: 115-119 °C(lit.)
中文名称: 
6-氨基喹啉
英文名称: 
6-Aminoquinoline
6-Quinolinamine
6-Quinolylamine
性质描述: 从水中得到含2分子结晶水的结晶,从乙醚得棱柱体结晶。无水物熔点为114℃,沸点187℃(1.6kPa),146(40Pa)。溶于乙醇、乙醚和氨,微溶于水和石油类。
生产方法: 由6-硝基喹啉还原而得。将6-硝基喹啉研细,投入还原锅内,逐渐加入硫化铵,同时搅拌,升温到90℃,回流1.5h。冷却至80℃排氨,防止冲料,排氨1h。滴加30%盐酸酸化使pH为3以下,静置1h,待硫完全析出后,倾出清液,静置,将沉淀用适量水洗涤,过滤,将滤饼并入清液,加30%氢氧化钠调节pH至13-14,静置2h。过滤,用10℃水洗涤至pH=8-9。将滤饼加热溶于50%乙醇中,用活性炭脱色,过滤,滤液倾入水中,冷却结晶,过滤,在60℃以下真空干燥,得6-氨基喹啉。
用途: 用作医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
A801263MACKLIN6-氨基喹啉97%24元/1g;   79元/5g;   366元/25g;   1425元/100g;   展开
储存:室温
状态:浅棕色晶体
A1370TCI6-Aminoquinoline>99.0%(T)380元/1G;   750元/5G;   展开

基本信息

纯度/分析方法>99.0%(T)
分子式/分子量C9H8N2 = 144.18
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气
Reaxys-RN113320
PubChem物质ID87562825
SDBS (AIST Spectral DB)39322
MDL编号MFCD00006803

技术规格

AppearanceLight yellow to Brown to Dark green powder to crystal
Purity(GC)min. 98.0 %
Purity(Nonaqueous Titration)min. 98.0 %
Melting point114.0 to 118.0 ℃

物性(参考值)

熔点116 ℃
沸点187 ℃/11 mmHg
溶解性(可溶于)甲醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
142367J&K6-Aminoquinoline99%295元/1G;   832元/5G;   3318元/25G;   展开

基本信息

分子式C9H8N2
分子量144.17
熔点115-119
沸点146
MDL编码MFCD00006803
Beilstein113320
EINECS 编号209-453-0

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
防范说明P305+P351+P338
WGK3
TSCA
L13819Alfa Aesar6-Aminoquinoline98%898元/1g;   2632元/5g;   10279元/25g;   展开

应用
6-Aminoquinoline was used as an internal standard in determining serum nicotine and cotinine simultaneously by using high-performance liquid chromatography (HPLC)-fluorometric detection with a postcolumn ultraviolet-photo irradiation system. It was also used as a fluorescent derivatizing agent for the detection of biochemicals and in the synthesis of tertiary N-methylated enaminonesa.

备注
Air sensitive. Store under inert gas. Store away from oxidizing agents, air.

基本信息

MDL
MFCD00006803

EINECS
209-453-0

分子式
C9H8N2

分子量
144.18

熔点
115-119°

沸点
146°/0.3mm

灵敏度
Air Sensitive. Ambient temperatures.

溶解性
Soluble in methanol, chloroform, ethanol, and benzene. Insoluble in water.

Beilstein
113320

GHS危害和防范说明

GHS符号

Hazard Statements
H301-H311-H332-H315-H319-H335
Toxic if swallowed.Toxic in contact with skin.Harmful if inhaled.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
20/21/22-36/37/38
Harmful by inhalation, in contact with skin and if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

欧盟危险品标志

TSCA

275581Sigma-Aldrich6-Aminoquinoline98%469.93元/1 G;   1231.59元/5 G;   展开

产品说明

应用

6-氨基喹啉可作为通过使用高效液相色谱(HPLC)-荧光检测(带柱后紫外光照射系统)同时测定血清尼古丁和可替宁的内标。它也可用作检测生物化学物质的荧光衍生剂,以及合成 N-甲基化烯胺酮叔胺。

包装

1, 5 g in glass bottle

基本信息

经验(实验)分子式C9H8N2
分子量144.17
Beilstein113320
EC 号209-453-0
MDL编号MFCD00006803
PubChem化学物质编号24856657
NACRESNA.22

产品性质

质量水平200
测定98%
bp146 ℃/0.3 mmHg (lit.)
mp115-119 ℃ (lit.)
SMILES stringNc1ccc2ncccc2c1
InChI1S/C9H8N2/c10-8-3-4-9-7(6-8)2-1-5-11-9/h1-6H,10H2
InChI keyRJSRSRITMWVIQT-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
045222Fluorochem6-Aminoquinoline98%264元/1g;   594元/5g;   1122元/10g;   2442元/25g;   展开

基本信息

CAS Number580-15-4
MDL NumberMFCD00006803

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P322: Specific measures (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P363: Wash contaminated clothing before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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