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关键词:       仅模糊查询
CAS: 58-33-3
分子式: C17H21ClN2S
分子量: 320.88
熔点: 227-230℃
中文名称: 
盐酸异丙嗪
盐酸普鲁米嗪
英文名称: 
10-(2-(dimethylamino)propyl)-phenothiazin monohydrochloride
10-(2-(dimethylamino)propyl)phenothiazine monohydrochloride
10-(2-dimethylamino-1-propyl)phenothiazine hydrochloride
10-(2-dimethylaminopropyl)phenothiazine hydrochloride
10-(3-dimethylaminoisopropyl)phenothiazine hydrochloride
n,n, alpha-trimethyl-10h-phenothiazine-10-ethanamin monohydrochloride
n,n,alpha-trimethyl-10h-phenothiazine-10-ethanamin monohydrochloride
atosil
diprasine
diprazin
dorme
fellozine
fenergan
ganphen
hl 8700
kinetosin
n-(2'-dimethylamino-2'-methyl)ethylphenothiazine hydrochloride
n-(2-dimethylaminopropyl-1)phenothiazine hydrochloride
phencen
phenergan hydrochloride
pipolfen
plletia
primine
promantine
promethazine hydrochloride
promethazine n-(2'-dimethylamino-2'-methylethyl)phenothiazine hydrochloride
promethiazin
promine
Phenergan
pyrethia
remsed
romegran hydrochloride
promethazine hydrochlorine
展开更多英文名
用途: 适用于各种过敏性疾病和孕期呕吐。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P797791MACKLIN盐酸异丙嗪10mM in DMSO185元/1ml;   展开
储存：-20°C, 密封, 干燥
P2029TCIPromethazine Hydrochloride>98.0%(T)(HPLC)520元/25G;   1685元/100G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C17H20N2S・HCl = 320.88
外观与形状(20℃)固体
应避免的情况光
相关CAS RN60-87-7
Reaxys-RN4166397
PubChem物质ID160871508
Merck Index (14)7786
MDL编号MFCD00012652

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %

物性(参考值)

熔点226 ℃
最大吸收波长297(H2O) nm
水溶性完全溶解
溶解性(易溶于)乙醇
溶解性(不溶于)乙醚

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H411 : 对水生生物有毒并具有长期持续影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P391 : 收集溢出物。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。

相关法规

RTECS#SO8225000

运输信息

UN编号UN3077
类别9
包装类别 III
监管条件代码(*)
372427J&KPromethazine Hydrochloride98%, 一种组胺H1受体拮抗剂447元/25G;   1454元/100G;   展开

基本信息

分子式C17H20N2S·HCl
分子量320.88
熔点224-228
MDL编码MFCD00012652
Beilstein4166397
Merck13,7878
EINECS 编号200-375-2

产品描述

Promethazine HCl 是一种强效的histamine H1受体拮抗剂,被用作镇静和抗过敏的药物。

靶点（IC50 & Targe）

H1 receptor

α-adrenergic receptor

安全信息

图形或危害标志
提示语Warning
危险说明H302
H332
H315
H317
H319
H335
H411
防范说明P261
P273
P280
P305+P351+P338
UN号码3077
危险分类9
包装等级III
WGK3
RTECSSO8225000
C25458Alfa AesarPromethazine Hydrochloride760元/5g;   1471元/25g;   4508元/100g;   展开

基本信息

Ref#
25458

分子式
C17H20N2S.HCl

分子量
86.95

GHS危害和防范说明

Hazard Statements
H302 H332 H315 H317 H319 H411

Precautionary Statements
P301+P330+P331 P312 P302+P352 P333+P313 P337+P313 P280

安全信息

危险等级
9

PHR1467SupelcoPromethazine HydrochloridePharmaceutical Secondary Standard; Certified Reference Material1461.17元/1 G;   展开

产品说明

一般描述

Promethazine hydrochloride belongs to the group of phenothiazine derivatives. It is commonly used as an antihistaminic for most prominently enhancing the anesthetic, sedative and analgesic effect of other drugs. It also shows antipyretic and antiemetic properties, when used in combination with paracetamol. It is also used to provide symptomatic relief of hypersensitivity reactions.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Promethazine hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectroanalytical technique.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA3015 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C17H20N2S · HCl
分子量320.88
Beilstein4166397
EC 号200-375-2
MDL编号MFCD00012652
PubChem化学物质编号329823397
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 421
traceable to PhEur P3400000
traceable to USP 1570009
储存温度2-8℃
SMILES stringCl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
InChI1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI keyXXPDBLUZJRXNNZ-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS05GHS07GHS09
警示用语：Danger
危险声明H302 - H317 - H318 - H411
预防措施声明P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
P3400000Promethazine HydrochlorideEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C17H20N2S · HCl
分子量320.88
Beilstein4166397
MDL编号MFCD00012652
PubChem化学物质编号329820173
NACRESNA.24

产品性质

等级pharmaceutical primary standard
agencyEP Reference Standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
InChI1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI keyXXPDBLUZJRXNNZ-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS05GHS07GHS09
警示用语：Danger
危险声明H302 - H317 - H318 - H411
预防措施声明P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
46682SupelcoPromethazine HydrochlorideVETRANAL®, analytical standard1326.69元/100 MG;   展开

产品说明

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C17H20N2S · HCl
分子量320.88
Beilstein4166397
EC 号200-375-2
MDL编号MFCD00012652
PubChem化学物质编号329756618

产品性质

等级analytical standard
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)clinical testing
格式neat
SMILES stringCl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
InChI1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI keyXXPDBLUZJRXNNZ-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS05GHS07GHS09
警示用语：Danger
危险声明H302 - H317 - H318 - H411
预防措施声明P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Y0000797Promethazine for peak identificationEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 5 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C17H20N2S · HCl
分子量320.88
Beilstein4166397
MDL编号MFCD00012652
PubChem化学物质编号329831155
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
InChI1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI keyXXPDBLUZJRXNNZ-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS05GHS07GHS09
警示用语：Danger
危险声明H302 - H317 - H318 - H411
预防措施声明P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
P4651Sigma-AldrichPromethazine Hydrochloride820.57元/25 G;   2174.31元/100 G;   展开

产品说明

生化/生理作用

H 1 组胺受体拮抗剂；CNS 抑制剂；抗胆碱能药。

特点和优势

该化合物由 Wyeth 开发 。要浏览其他制药公司开发的化合物列表批准的药物/候选药物的列表， 点击这里 。

其他说明

溶解度：易溶于水、热无水乙醇和氯仿。几乎不溶于乙醚、丙酮和乙酸乙酯。

外形

外观：白色或淡黄色，无味，结晶性粉末，缓慢氧化，长期暴露于空气中，呈蓝色。

基本信息

经验(实验)分子式C17H20N2S · HCl
分子量320.88
Beilstein4166397
EC 号200-375-2
MDL编号MFCD00012652
PubChem化学物质编号24277802
NACRESNA.77

产品性质

质量水平200
创始人Wyeth
SMILES stringCl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
InChI1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI keyXXPDBLUZJRXNNZ-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS05GHS07GHS09
警示用语：Danger
危险声明H302 - H317 - H318 - H411
预防措施声明P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
1570009USPPromethazine HydrochlorideUnited States Pharmacopeia (USP) Reference Standard3231.47元/500 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C17H20N2S · HCl
分子量320.88
Beilstein4166397
MDL编号MFCD00012652
PubChem化学物质编号329750972

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度−20℃
SMILES stringCl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
InChI1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI keyXXPDBLUZJRXNNZ-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS05GHS07GHS09
警示用语：Danger
危险声明H302 - H317 - H318 - H411
预防措施声明P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
BP412Promethazine HydrochlorideBritish Pharmacopoeia (BP) Reference Standard2144.18元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C17H20N2S · HCl
分子量320.88
Beilstein4166397
EC 号200-375-2
MDL编号MFCD00012652

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringCl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
InChI1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI keyXXPDBLUZJRXNNZ-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS05GHS07GHS09
警示用语：Danger
危险声明H302 - H317 - H318 - H411
预防措施声明P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9