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CAS: 58-14-0
分子式: C12H13ClN4
分子量: 248.71
熔点: 233-234 °C
中文名称: 
息疟定
达拉匹林
乙胺嘧啶
乙嘧啶
英文名称: 
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
2,4-Pyrimidinediamine,5-(4-chlorophenyl)-6-ethyl-
Pyrimidine,2,4-diamino-5-(p-chlorophenyl)-6-ethyl-
5-(4-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(P-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
Pirimetamin
Pyrimethamin
pyrimethamine(INN)
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diyldiamine
5-(4-Chlorphenyl)-6-ethyl-2,4-pyrimidindiamin
5-(p-chlorophenyl)-6-ethyl-4-pyrimidinediamine
2,4-diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
2,4-diamino-5-p-chlorophenyl-6-ethylpyrimidine
4753 r.p.
5-(4'-chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
bw 50-63
chloridin
chloridine
chloridyn
darachlor
darapram
daraprim
daraprime
diaminopyritamin
erbaprelina
khloridin
malacid
malocid
malocide
nci-c01683
nsc 3061
pirimecidan
pirimetamina
pyrimethamine
tindurin
wr 2978
展开更多英文名
用途: 抗疟药,用于疟疾的病因预防及抗复发治疗
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P816537MACKLIN乙胺嘧啶分析对照品155元/5g;   展开
储存:2~8°C
P875257MACKLIN乙胺嘧啶98%36元/5g;   118元/25g;   309元/100g;   1259元/500g;   展开
储存:2~8°C
状态:白色-几乎白色晶体-粉末
P794530MACKLIN乙胺嘧啶10mM in DMSO224元/1ml;   展开
储存:-20°C
P2037TCIPyrimethamine>98.0%(T)(HPLC)345元/1G;   1090元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C12H13ClN4 = 248.71
外观与形状(20℃)固体
Reaxys-RN219864
PubChem物质ID253660065
Merck Index (14)7985
MDL编号MFCD00057350

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %
Melting point239.0 to 243.0 ℃

物性(参考值)

熔点241 ℃
最大吸收波长276 nm
水溶性不溶
溶解度(极微溶)乙醇

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H361 : 怀疑对生育能力或胎儿造成伤害。
H411 : 对水生生物有毒并具有长期持续影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P391 : 收集溢出物。
P308 + P313 : 如接触到或有疑虑:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#UV8140000

运输信息

UN编号UN3077
类别9
包装类别 III
监管条件代码(*)
571600J&KPyrimethamine98%92元/1G;   357元/5G;   展开

基本信息

分子式C12H13ClN4
分子量248.71
MDL编码MFCD00057350
Beilstein219864
EINECS 编号200-364-2

安全信息

图形或危害标志
提示语Warning
危险说明H302
H361
H411
防范说明P281
P301+P312+P330
UN号码3077
危险分类9
包装等级III
WGK3
46706SupelcoPyrimethamineVETRANAL®, analytical standard761.09元/250 MG;   展开

产品说明

应用

有关合适仪器技术的更多信息,请参考产品′s分析证书。如需进一步支持,请联系技术服务。

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C12H13ClN4
分子量248.71
Beilstein219864
EC 号200-364-2
MDL编号MFCD00057350
PubChem化学物质编号329756622
NACRESNA.24

产品性质

等级analytical standard
质量水平200
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)clinical testing
格式neat
SMILES stringCCc1nc(N)nc(N)c1-c2ccc(Cl)cc2
InChI1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
InChI keyWKSAUQYGYAYLPV-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
P4200000PyrimethamineEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 250 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C12H13ClN4
分子量248.71
Beilstein219864
MDL编号MFCD00057350
PubChem化学物质编号329820201
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCCc1nc(N)nc(N)c1-c2ccc(Cl)cc2
InChI1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
InChI keyWKSAUQYGYAYLPV-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1589007USPPyrimethamineUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C12H13ClN4
分子量248.71
Beilstein219864
MDL编号MFCD00057350
PubChem化学物质编号329750999
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCCc1nc(N)nc(N)c1-c2ccc(Cl)cc2
InChI1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
InChI keyWKSAUQYGYAYLPV-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP1227PyrimethamineBritish Pharmacopoeia (BP) Reference Standard2098.58元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C12H13ClN4
分子量248.71
Beilstein219864
MDL编号MFCD00057350

产品性质

质量水平100
manufacturer/tradenameBP
储存温度2-8℃
SMILES stringCCc1nc(N)nc(N)c1-c2ccc(Cl)cc2
InChI1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
InChI keyWKSAUQYGYAYLPV-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
211965Fluorochem5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4-diamine95%506元/5g;   968元/10g;   2288元/25g;   展开

基本信息

CAS Number58-14-0
MDL NumberMFCD00057350
Melting Point241℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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