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CAS: 56-53-1
分子式: C18H20O2
分子量: 268.35
熔点: 169-175℃
中文名称: 
已烯雌酚
乙芪酚
乙烯雌酚
乙烯雌激酚
二羟二乙基代乙芪酚
二乙基己烯雌酚
二乙基二苯乙烯雌激酚
己烯雌酚
英文名称: 
(E)-3,4-Bis(4-hydroxyphenyl)-3-hexene
alpha,alpha'-diethyl-4'-stilbenediol
3,4'(4,4'-dihydroxyphenyl)hex-3-ene
3,4-bis(p-hydroxyphenyl)-3-hexene
3,4-bis(parahydroxyphenyl)-3-hexene
3,4-bis(p-hydroxyphenyl)-3-hexen
4,4'-(1,2-diethyl-1,2-ethenediyl)bis-phenol
4,4'-dihydroxy-alpha,beta-diethylstilbene
4,4'-dihydroxydiethylstilbene
alpha'-diethyl-4'-stilbenedio (e)-alpha
2,2'-diethyl-4'-stilbenediol
acnestrol
agostilben
alpha,alpha'-diethyl-(e)-4,4'-stilbenediol
alpha,alpha'-diethyl-4,4'-stilbenediol
alpha,alpha'-diethylstilbenediol
antigestil
bio-des
bufon
climaterine
comestrol
comestrol estrobene
cyren
cyren a
dawe's destrol
deb
des (synthetic estrogen)
di-estryl
dibestrol
dibestrol "2" premix
dibestrol '2' premix
dicorvin
diethylstilbesterol
diethylstilbestrol
diethylstilboesterol
dietilestilbestrol
distilbene
domestrol
dyestrol
estilbin ''mco''
estilbin mco
estrobene
estromenin
estrosyn
fonatol
grafestrol
gynopharm
hi-bestrol
idroestril
iscovesco
makarol
menostilbeen
micrest
microest
milestrol
neo-oestranol 1
neo-oestranol i
nsc-3070
oekolp
oestrogenine
oestrol vetag
oestromenin
oestromensil
oestromensyl
oestromienin
oestromon
pabestrol
palestrol
percutatrine oestrogenique iscovesco
2-diethyl-1,2-ethenediyl)bis-4'-( (e)-phenol
4'-(1,2-diethyl-1,2-ethenediyl)bis- (e)-pheno
protectona
rcra waste number u089
rumestrol 1
rumestrol 2
sedestran
serral
sexocretin
sibol
sintestrol
stibilium
stil
stil-rol
stilbestrol
stilbetin
stilboefral
stilboestroform
stilboestrol
stilbol
stilkap
synestrin
synthoestrin
synthofolin
syntofolin
tampovagan stilboestrol
trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol
trans-alpha,alpha'-diethyl-4,4'-stilbenediol
trans-diethylstilbesterol
trans-diethylstilbestrol
trans-diethylstilboesterol
tylosterone
vagestrol
(E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol
phenol,4,4'-(1,2-diethyl-1,2-ethendiyl)bis-,(E)-
3,4-bis-(4-hydroxy-phenyl)-trans-hex-3-ene
Diethylstilbene-4.4'-diol
Diethylstilboestrol
4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol
展开更多英文名
用途: 激素类药。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P808018MACKLIN己烯雌酚标准物质200μg/mL，介质：甲醇115元/5ml;   展开
储存：2~8°C
状态：白色至灰白色粉末
D796784MACKLIN己烯雌酚10mM in DMSO139元/1ml;   展开
储存：-20°C
状态：白色至灰白色粉末
D798843MACKLIN己烯雌酚分析对照品, ≥99.5%(HPLC)358元/50mg;   展开
储存：室温
状态：白色至灰白色粉末
D807246MACKLIN己烯雌酚99%54元/1g;   155元/5g;   608元/25g;   1935元/100g;   8888元/500g;   展开
储存：2~8°C
状态：白色至灰白色粉末
479297J&KDiethylstilbestrol99%815元/1G;   2142元/5G;   8030元/25G;   展开

基本信息

分子式C18H20O2
分子量268.35
MDL编码MFCD00002373
Beilstein2056095
Merck14,3129
EINECS 编号200-278-5

安全信息

图形或危害标志
提示语Danger
危险说明H351
H360D
防范说明P201
P281
P308+P313
UN号码2811
危险分类6.1
包装等级III
WGK3
RTECSWJ5600000
R10791Alfa AesarStilbestrol; Diethylstilbestrol Standard solution100ppm210元/1ml;   展开

安全信息

危险等级
3

R11889Alfa AesarStilbestrol; Diethylstilbestrol,1000ppm440元/1ml;   展开

安全信息

危险等级
3

D4628Sigma-AldrichDiethylstilbestrol≥99% (HPLC)1274.2元/1 G;   4094.18元/5 G;   6141.27元/10 G;   14990元/25 G;   展开

产品说明

应用

己烯雌酚已用于:

  • 通过定量测定内源性雌激素调节的标记基因的表达水平来评估己烯雌酚的雌激素活性
  • 在生物发光酵母生物报告基因检测试( bioluminescent yeast bioreporter assay，BLYES)中评估雌激素、雄激素和毒性反应
  • 检测其对黑素细胞增殖和酪氨酸酶活性的影响

生化/生理作用

己烯雌酚是一种具有致癌性质的合成雌激素。它能导致叙利亚仓鼠患肾透明细胞癌。它能导致人类患乳腺癌、阴道和宫颈的透明细胞腺癌(CCA)以及生殖异常的风险增加。可用于治疗前列腺癌，阻止睾酮的产生。

基本信息

经验(实验)分子式C18H20O2
分子量268.35
Beilstein2056095
EC 号200-278-5
MDL编号MFCD00002373
PubChem化学物质编号24893887
NACRESNA.77

产品性质

质量水平200
测定≥99% (HPLC)
SMILES stringCC\C(c1ccc(O)cc1)=C(\CC)c2ccc(O)cc2
InChI1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+
InChI keyRGLYKWWBQGJZGM-ISLYRVAYSA-N
Gene Informationhuman ... ESR1(2099), ESR2(2100), ESRRG(2104)
mouse ... Esr1(13982)
rat ... Ar(24208), Esr1(24890)

安全信息

象形图GHS07GHS08GHS09
警示用语：Danger
危险声明H315 - H319 - H335 - H350 - H360 - H410
预防措施声明P201 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
46207SupelcoDiethylstilbestrolVETRANAL®, analytical standard458.07元/250 MG;   展开

产品说明

一般描述

Diethylstilbestrol (DES) belongs to the synthetic oestrogens class of compounds.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
DES has been used as a reference standard for the determination of DES in:

  • Dairy products by QuEChERS (quick, easy, cheap, effective, rugged, and safe) extraction procedure and ultra-high performance liquid chromatography-triple quadrupole mass spectrometry (UHPLC-QqQ MS/MS) equipped with electrospray ionization (ESI) and multiple reaction monitoring (MRM) mode of detection.
  • Water samples by magnetic micro-dispersive solid-phase extraction (m-μSPE) and HPLC-MS.

It may be used as a reference standard for the analysis of DES in
  • Aquatic products by modified QuEChERS extraction and multiplug filtration clean-up (m-PFC) followed by LC-ESI-MS/MS with MRM mode of detection.
  • Milk samples by vortex-assisted hollow fibre liquid-phase microextraction (VA-HF-LPME) and HPLC with diode array detection (HPLC-DAD).

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C18H20O2
分子量268.35
Beilstein2056095
EC 号200-278-5
MDL编号MFCD00002373
PubChem化学物质编号329757101
NACRESNA.24

产品性质

等级analytical standard
质量水平200
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCC\C(c1ccc(O)cc1)=C(\CC)c2ccc(O)cc2
InChI1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+
InChI keyRGLYKWWBQGJZGM-ISLYRVAYSA-N
Gene Informationhuman ... ESR1(2099)

安全信息

象形图GHS07GHS08GHS09
警示用语：Danger
危险声明H315 - H319 - H335 - H350 - H360FD - H410
预防措施声明P201 - P202 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
1195001USPDiethylstilbestrolUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C18H20O2
分子量268.35
Beilstein2056095
MDL编号MFCD00002373
PubChem化学物质编号329749584
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCC\C(c1ccc(O)cc1)=C(\CC)c2ccc(O)cc2
InChI1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+
InChI keyRGLYKWWBQGJZGM-ISLYRVAYSA-N
Gene Informationhuman ... ESR1(2099)

安全信息

象形图GHS07GHS08GHS09
警示用语：Danger
危险声明H315 - H319 - H335 - H350 - H360 - H410
预防措施声明P201 - P280 - P305 + P351 + P338 - P308 + P313
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
D1500000DiethylstilbestrolEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C18H20O2
分子量268.35
Beilstein2056095
MDL编号MFCD00002373
PubChem化学物质编号329798701
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCC\C(c1ccc(O)cc1)=C(\CC)c2ccc(O)cc2
InChI1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+
InChI keyRGLYKWWBQGJZGM-ISLYRVAYSA-N
Gene Informationhuman ... ESR1(2099)

安全信息

象形图GHS07GHS08GHS09
警示用语：Danger
危险声明H315 - H319 - H335 - H350 - H360FD - H410
预防措施声明P202 - P261 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
BP859DiethylstilbestrolBritish Pharmacopoeia (BP) Reference Standard2144.18元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C18H20O2
分子量268.35
Beilstein2056095
MDL编号MFCD00002373
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringCC\C(c1ccc(O)cc1)=C(\CC)c2ccc(O)cc2
InChI1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+
InChI keyRGLYKWWBQGJZGM-ISLYRVAYSA-N
Gene Informationhuman ... ESR1(2099)

安全信息

象形图GHS07GHS08GHS09
警示用语：Danger
危险声明H315 - H319 - H335 - H350 - H360 - H410
预防措施声明P201 - P261 - P273 - P280 - P308 + P313 - P391
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
AS-E0540AccuStandardDiethylstilbestrol,1000 μg/mL in Acetonitrile1000 μg/mL in Acetonitrile494元/1mL;   展开
Diethylstilbestrol己烯雌酚56-53-11 mg/mL
240482FluorochemDiethyl stilbestrol95%682元/1g;   2244元/5g;   3784元/10g;   7568元/25g;   展开

基本信息

CAS Number56-53-1
MDL NumberMFCD00002373

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H341: Suspected of causing genetic defects ..
H350: May cause cancer ..
H360: May damage fertility or the unborn child ..
H371: May cause damage to organs : Liver, Cardiovascular system..
H411: Toxic to aquatic life with long lasting effects.
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear .
P281: Use personal protective equipment as required.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P309: IF exposed or if you feel unwell: .
P309 + P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P311: Call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P391: Collect spillage.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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