| CAS: | 55976-95-9 | |||||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||
| F7807 | Sigma-Aldrich | Prostaglandin F Synthase human | recombinant, expressed in E. coli, ≥90% (SDS-PAGE) | 5580.84元/50 μG; | 展开 | ||||||||||||||||||||||||||||||||||||
产品说明 应用 Prostaglandin F synthase (PGF synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. Prostaglandin F synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. PGF synthase is also used to study kidney and renal cell carcinoma . 生化/生理作用 PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways . 单位定义 One unit is defined as the amount of enzyme required to produce 1 μmol of NADP per minute at 37℃ in 50 mM KPO4 pH 7.2 containing 250 μM NADPH and 25 μM 9,10-phenanthrenequinone 基本信息
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