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CAS: 55976-95-9
英文名称: 
prostaglandin f synthase human
indanol dehydrogenase
aldo-keto reductase family 1 member c3
akr1c3
17-beta-hydroxysteroid dehydrogenase type 5
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货号品牌产品名称规格包装、参考价格详情
F7807Sigma-AldrichProstaglandin F Synthase humanrecombinant, expressed in E. coli, ≥90% (SDS-PAGE)5580.84元/50 μG;   展开

产品说明

应用

Prostaglandin F synthase (PGF synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. Prostaglandin F synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. PGF synthase is also used to study kidney and renal cell carcinoma .

生化/生理作用

PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways .

单位定义

One unit is defined as the amount of enzyme required to produce 1 μmol of NADP per minute at 37℃ in 50 mM KPO4 pH 7.2 containing 250 μM NADPH and 25 μM 9,10-phenanthrenequinone

基本信息

酶学委员会(EC)编号1.1.1.188 ( BRENDA | IUBMB )
NACRESNA.54

产品性质

质量水平200
重组expressed in E. coli
描述contains a C-terminal hexahistidine tag
测定≥90% (SDS-PAGE)
形式liquid
specific activity≥0.4 μmol/mg protein
分子量 ~37 kDa
NCBI登记号NP_003730
运输dry ice
储存温度−70℃
Gene Informationhuman ... AKR1C3(8644)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
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