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CAS: 55750-63-5
分子式: C14H16N2O6
分子量: 308.29
熔点: 70-73℃
英文名称: 
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
6-Maleimidohexanoic acid N-succinimidyl ester
N-Succinimidyl 6-Maleimidohexanoate
6-Maleimidocaproic Acid N-Succinimidyl Ester
N-(6-Maleimidocaproyloxy)succinimide
n-succinimidyl 6-maleimidocaproate
推荐供应商
货号品牌产品名称规格包装、参考价格详情
M824596MACKLIN6-(马来酰亚胺基)己酸琥珀酰亚胺酯98%27元/250mg;   83元/1g;   278元/5g;   1034元/25g;   展开
储存:2~8℃
状态:白色到浅黄色粉末
S0428TCIN-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]>98.0%(N)490元/1G;   1990元/5G;   6990元/25G;   展开

基本信息

纯度/分析方法>98.0%(N)
分子式/分子量C14H16N2O6 = 308.29
外观与形状(20℃)固体
储存温度-20℃
储存在惰性气体下存放于惰性气体之中
应避免的情况光,湿气 (分解),加热
Reaxys-RN1499815
PubChem物质ID87575913
MDL编号MFCD00043043

技术规格

AppearanceWhite to Light yellow powder to crystaline
Purity(HPLC)min. 95.0 area%
Purity(with Total Nitrogen)min. 98.0 %
Melting point69.0 to 74.0 ℃

物性(参考值)

熔点71 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
245256J&K6-Maleimidohexanoic acid N-hydroxysuccinimide ester98%1286元/100MG;   4589元/1G;   展开

基本信息

分子式C14H16N2O6
分子量308.29
熔点70-73
MDL编码MFCD00043043
存储条件Freezer -20℃

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
TSCA
H65996Alfa Aesar6-Maleimidocaproic acid N-succinimidyl ester95%2372元/250mg;   7557元/1g;   展开

基本信息

MDL
MFCD00043043

分子式
C14H16N2O6

分子量
308.29

熔点
69-74°

形态
Solid

Beilstein
1499815

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA

568600Sigma-Aldrich6-Maleimidohexanoic acid N-hydroxysuccinimide ester98%4915.74元/500 MG;   展开

产品说明

应用

6-Maleimidohexanoic acid N-hydroxysuccinimide ester can be used in:

  • Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction.
  • Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent.
  • Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.

包装

500 mg in amber glass bottle

基本信息

经验(实验)分子式C14H16N2O6
分子量308.29
Beilstein1499815
MDL编号MFCD00043043
PubChem化学物质编号24880215
NACRESNA.22

产品性质

质量水平100
测定98%
reaction suitabilityreagent type: cross-linking reagent
mp70-73 ℃ (lit.)
储存温度−20℃
SMILES stringO=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
InChI1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI keyVLARLSIGSPVYHX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
M9794Sigma-Aldrich6-Maleimidohexanoic acid N-hydroxysuccinimide ester≥98%, powder1453元/10 MG;   2177.51元/25 MG;   7329.43元/100 MG;   展开

产品说明

包装

10, 25, 100 mg in glass bottle

应用

一种插入了具有胺和巯基反应性延长间隔基的异双功能性交联剂。通常,首先通过在pH7.5(6.5-8.5)缓冲的酰胺键与含有伯胺的分子偶联。第二偶联对于通过在pH6.8(6.5-7.0)缓冲的硫醚键而含有游离巯基的分子是特异性的。可用于制备酶免疫耦合物和半抗原载体分子耦合物。包含9个原子连接子。与芳族间隔基相比,延伸的脂族间隔基在偶联之前可稳定马来酰亚胺。

基本信息

经验(实验)分子式C14H16N2O6
分子量308.29
Beilstein1499815
MDL编号MFCD00043043
PubChem化学物质编号329818098
NACRESNA.25

产品性质

质量水平200
测定≥98%
形式powder
reaction suitabilityreagent type: cross-linking reagent
mp70-73 ℃ (lit.)
溶解性chloroform: 100 mg/mL
DMF: soluble (lit.)(lit.)
储存温度−20℃
SMILES stringO=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
InChI1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI keyVLARLSIGSPVYHX-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H315 - H319 - H335 - H351
预防措施声明P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
63177Sigma-Aldrich6-Maleimidohexanoic acid N-hydroxysuccinimide ester≥98.0% (HPLC)1672.89元/25 MG;   5906.32元/100 MG;   展开

产品说明

应用

6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

其他说明

Reagent for cross-linking and immobilisation of proteins

基本信息

经验(实验)分子式C14H16N2O6
分子量308.29
Beilstein1499815
MDL编号MFCD00043043
PubChem化学物质编号329759804

产品性质

质量水平200
测定≥98.0% (HPLC)
reaction suitabilityreagent type: cross-linking reagent
mp67-73 ℃
70-73 ℃ (lit.)
储存温度−20℃
SMILES stringO=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
InChI1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI keyVLARLSIGSPVYHX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
079601FluorochemN-Succinimidyl 6-maleimidohexanoate98%1386元/1g;   4686元/5g;   14102元/25g;   展开

基本信息

CAS Number55750-63-5
MDL NumberMFCD00043043
Melting Point65-73℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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