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CAS: 554-62-1
分子式: C18H39NO3.HCl
分子量: 353.97
沸点: 483.7±40 °C
熔点: 102 °C
英文名称: 
phytosphingosine
phytosphingosine hydrochloride
用途: 植物鞘氨醇是一种长链类鞘氨醇碱,广泛存在于酵母、植物和动物(包括哺乳动物)中。在酵母中,它可能通过激活 AGC 型蛋白激酶(Pkh1、Pkh2、Ypk1、Ypk2 和 Sch9)参与介导热应激反应。它在人类癌细胞系中具有促凋亡作用。PHS 直接或通过激活 p38MAPK 途径诱导 ΔΨm,并从线粒体释放细胞色素 c。这导致 caspase 9 激活,然后 caspase 3 激活和程序性细胞死亡
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P838474MACKLIN植物鞘胺醇98%30元/50mg;   100元/250mg;   227元/1g;   980元/5g;   3635元/25g;   展开
储存:-20°C,避光,密封
状态:固体
P1765TCIPhytosphingosine>98.0%(T)990元/1G;   2650元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C18H39NO3 = 317.51
外观与形状(20℃)固体
Reaxys-RN1725301
PubChem物质ID87560462
MDL编号MFCD00079232

技术规格

AppearanceWhite to Light yellow to Light orange powder to crystaline
Purity(Nonaqueous Titration)min. 98.0 %
Specific rotation [a]20/D+6.0 to +12.0 deg(C=1, Pyridine)

物性(参考值)

熔点102 ℃
比旋光度 [α]D9° (C=1,Pyridine)
346201J&KPhytosphingosine95%779元/1G;   2033元/5G;   9356元/25G;   展开

基本信息

分子式C18H39NO3
分子量317.51
熔点102
比旋光度([α]20D)+6.0 to +12.0 (C=1, Pyridine)
MDL编码MFCD02259274
Beilstein1725301
存储条件Freezer -20℃

安全信息

防范说明P262
P2795Sigma-AldrichPhytosphingosine hydrochloride4266.65元/5 MG;   展开

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

植物鞘氨醇是一种长链类鞘氨醇碱,广泛存在于酵母、植物和动物(包括哺乳动物)中。在酵母中,它可能通过激活 AGC 型蛋白激酶(Pkh1、Pkh2、Ypk1、Ypk2 和 Sch9)参与介导热应激反应。它在人类癌细胞系中具有促凋亡作用。PHS 直接或通过激活 p38MAPK 途径诱导 ΔΨm,并从线粒体释放细胞色素 c。这导致 caspase 9 激活,然后 caspase 3 激活和程序性细胞死亡。

基本信息

经验(实验)分子式C18H39NO3 · HCl
分子量353.97
MDL编号MFCD06804643
PubChem化学物质编号24898363
NACRESNA.25

产品性质

质量水平200
环保替代产品得分old score: 19
new score: 9
Find out more about DOZN™ Scoring
环保替代产品特性Less Hazardous Chemical Syntheses
Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
环保替代产品分类Re-engineered
储存温度−20℃
SMILES stringCl.CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO
InChI1S/C18H39NO3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20;/h16-18,20-22H,2-15,19H2,1H3;1H/t16-,17+,18-;/m0./s1
InChI keyGDKAAHDFPOWGQE-RXQQAGQTSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
324042Fluorochem(2S,3S,4R)-2-Aminooctadecane-1,3,4-triol95%1100元/1g;   2860元/5g;   展开

基本信息

CAS Number554-62-1
MDL NumberMFCD02259274
Melting Point102℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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