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CAS: 55-22-1
分子式: C6H5NO2
分子量: 123.11
沸点: 260℃(15
熔点: 310-315℃
中文名称: 
γ-吡啶甲酸
4-吡啶羧酸
吡啶-4-甲酸
异尼克酸
托灭酸
吡啶-4-羧酸
英文名称: 
isonicotinic acid
4-carboxypyridine
4-picolinic acid
4-pyridinecarboxylic acid
acide iso-nicotinique
gamma-picolinic acid
gamma-pyridinecarboxylic acid
p-pyridinecarboxylic acid
iso-Nicotinic acid
-Picolinic acid
性质描述: 白色针状结晶。熔点319℃(315℃)。较溶于热水,水溶液的pH值为3.6,微溶于冷水,几乎不溶于沸醇、苯及醚。能升华。无气味。
生产方法: 用4-甲基吡啶为原料,以五氧化二钒为催化剂进行连续氧化而制得。工业品异烟酸的纯度为95%以上,上述方法的收率为70-75%。每吨产品消耗4-甲基吡啶1070kg。
用途: 该品为医药中间体。主要用于制取异烟肼(雷米封)。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
I766200MACKLIN异烟酸-吡唑酮溶液280元/100ml;   550元/500ml;   展开
储存:室温, 避光
I811605MACKLIN异烟酸试剂级, 99%39元/25g;   65元/100g;   181元/500g;   600元/2.5kg;   2224元/10kg;   5498元/25kg;   2150元/12X500g;   展开
储存:室温
状态:白色到灰白色粉末
I0207TCIIsonicotinic Acid>99.0%(T)(HPLC)160元/25G;   615元/500G;   展开

基本信息

纯度/分析方法>99.0%(T)(HPLC)
分子式/分子量C6H5NO2 = 123.11
外观与形状(20℃)固体
Reaxys-RN109599
PubChem物质ID87571586
SDBS (AIST Spectral DB)10753
Merck Index (14)5187
MDL编号MFCD00006429

技术规格

AppearanceWhite powder to crystal
Purity(HPLC)min. 99.0 area%
Purity(Neutralization titration)min. 99.0 %

物性(参考值)

熔点315 ℃
溶解度(极微溶)乙醚,苯

安全信息

图形或危害标志
信号词警告
危险性说明H303 : 吞咽可能有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P312 : 如感觉不适,呼叫急救中心/医生。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#NS1103000
140345J&KIsonicotinic Acid99%60元/5G;   63元/25G;   195元/100G;   540元/500G;   展开

基本信息

分子式C6H5NO2
分子量123.11
熔点300
MDL编码MFCD00006429
Beilstein109599
Merck14,5187
EINECS 编号200-228-2

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSNS1103000
TSCA
A18109Alfa AesarIsonicotinic Acid99%289元/100g;   1022元/500g;   4964元/2500g;   展开

应用
It acts as an useful isomer of nicotinic acid.

备注
Store away from oxidizing agents and reducing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

基本信息

MDL
MFCD00006429

EINECS
200-228-2

分子式
C6H5NO2

分子量
123.11

熔点
ca 310° subl.

沸点
260°/15mm

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in water (6 mg/ml), and 2 N NH4OH (5%). Insoluble in ether, benzene, and boiling alcohol.

Beilstein
109599

Merck
14,5187

GHS危害和防范说明

GHS符号

Hazard Statements
H303-H315-H319-H335
May be harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
NS1103000

TSCA

C12259Alfa AesarIsonicotinic Acid99%492元/100g;   1694元/500g;   6682元/2.5kg;   展开

基本信息

Ref#
12259

MDL
6429

分子式
C6 H5 N O2

分子量
123.11

形态
Powder

I17508Sigma-AldrichIsonicotinic Acid99%368.98元/5 G;   436.18元/100 G;   1174.31元/500 G;   展开

产品说明

应用

异烟酸(IN)可以用作:

  • 一锅四组分缩合反应中的有机催化剂,用于合成吡喃并吡唑类杂环化合物。
  • 通过水热法制备卤化铜(I)配位聚合物[CuBr(IN)]n的有机配体。
  • 合成具有强大抗疟疾活性的阳离子二聚体的原料。

包装

5, 100, 500 g in poly bottle

基本信息

经验(实验)分子式C6H5NO2
分子量123.11
Beilstein109599
EC 号200-228-2
MDL编号MFCD00006429
PubChem化学物质编号24895943
NACRESNA.22

产品性质

质量水平200
测定99%
形式powder
technique(s)cell culture | plant: suitable
mp≥300 ℃ (lit.)
SMILES stringOC(=O)c1ccncc1
InChI1S/C6H5NO2/c8-6(9)5-1-3-7-4-2-5/h1-4H,(H,8,9)
InChI keyTWBYWOBDOCUKOW-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P305 + P351 + P338
危险分类Eye Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
8.00736Sigma-Aldrich4-Pyridinecarboxylic acidfor synthesis226.45元/5 G;   1131.72元/250 G;   展开

基本信息

经验(实验)分子式C6H5NO2
分子量123.11
MDL编号MFCD00006429
EC索引号200-228-2

产品性质

质量水平200
测定≥98% (HPLC)
形式powder
效能5000 mg/kg LD50, oral (Rat)
pH值(酸碱度)3-4 (20 ℃, 6 g/L in H2O, saturated solution)
bp260 ℃/20 hPa
mp315-319 ℃
溶解性 6 g/L
堆积密度500 kg/m3
储存温度no temp limit
InChI1S/C6H5NO2/c8-6(9)5-1-3-7-4-2-5/h1-4H,(H,8,9)
InChI keyTWBYWOBDOCUKOW-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
573677AmethystIsonicotinic Acid99%, 用于合成50元/5G;   59元/25G;   94元/100G;   280元/500G;   822元/2.5KG;   展开

基本信息

分子式C6H5NO2
分子量123.11
熔点≥300
MDL编码MFCD00006429
Beilstein109599
Merck14,5187
EINECS 编号200-228-2

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSNS1103000
TSCA
045226FluorochemIsonicotinic Acid98%374元/50g;   660元/100g;   展开

基本信息

CAS Number55-22-1
MDL NumberMFCD00006429
Melting Point>300℃
Density1.5

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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