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CAS: 541-59-3
分子式: C4H3NO2
分子量: 97.07
沸点: 97-103°C 5mm
熔点: 90-94℃
中文名称: 
马来酰亚胺
顺丁烯二酰亚胺
英文名称: 
maleimide
1h-pyrrole-2,5-dione
maleic imide
maleinimide
pyrrole-2,5-dione
性质描述: 片状结晶。熔点93-95℃。溶于水、乙醇和乙醚。易升华。
生产方法: 由吡咯与重铬酸钾反应而得。将1177g重铬酸钾溶于1200ml水及712ml浓硫酸中,加热至35℃,将54g吡咯在搅拌下慢慢加入,反反温度不超过50℃。加毕,在40-50℃保温反应至无吡咯气味时为止。冷却,用玻璃棉去反应生成的少量焦油,滤渣用热水洗涤。过滤、洗液用乙醚提取,提取液经无水硫酸钠干燥后,蒸发回收乙醚,得粗品结晶。用真空升华可得7g纯白结晶成品。
用途: 用于有机合成。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
M812744MACKLIN马来酰亚胺98.5%46元/5g;   90元/10g;   136元/25g;   538元/100g;   2557元/500g;   展开
储存:2~8°C,密封
状态:白色或几乎结晶粉末
M792805MACKLIN马来酰亚胺10mM in DMSO186元/1ml;   展开
储存:-20°C
M0018TCIMaleimide>98.0%(T)545元/5G;   1530元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C4H3NO2 = 97.07
外观与形状(20℃)固体
Reaxys-RN106910
PubChem物质ID87572137
SDBS (AIST Spectral DB)3678
MDL编号MFCD00005494

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Neutralization titration)min. 98.0 %
Melting point92.0 to 95.0 ℃
Solubility in Methanolalmost transparency

物性(参考值)

熔点94 ℃
沸点125 ℃/10 mmHg
最大吸收波长280(EtOH) nm
溶解性(可溶于)甲醇

安全信息

图形或危害标志
信号词危险
危险性说明H301 : 吞咽会中毒。
H314 : 造成严重皮肤灼伤和眼损伤。
H317 : 可能造成皮肤过敏反应。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P272 : 受沾染的工作服不得带出工作场地。
P260 : 不要吸入粉尘或烟雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P303 + P361 + P353 : 如皮肤(或头发)沾染:立即脱掉所有沾污的衣物。用水清洗皮肤/淋浴。
P333 + P313 : 如发生皮肤刺激或皮疹:求医/就诊。
P301 + P330 + P331 : 如误吞咽:漱口。不要诱导呕吐。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P304 + P340 + P310 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。立即呼叫急救中心/医生。
P305 + P351 + P338 + P310 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。
P405 : 存放处须加锁。

相关法规

RTECS#ON4800000

运输信息

UN编号UN2923
类别8 / 6.1
包装类别 II
监管条件代码(*)
436703J&KMaleimide98%418元/5G;   1111元/25G;   3653元/100G;   展开

基本信息

分子式C4H3NO2
分子量97.07
熔点91-93
MDL编码MFCD00005494
Beilstein106910
EINECS 编号208-787-4

安全信息

图形或危害标志
提示语Danger
危险说明H301
H314
H317
防范说明P280
P301+P310
P305+P351+P338
P310
UN号码2923
危险分类8
次要危险性6.1
包装等级II
WGK3
RTECSON4800000
TSCA
A13135Alfa AesarMaleimide98+%1217元/5g;   2529元/25g;   9836元/50g;   0元/250g;   展开

应用
Reacts quantitatively with sulfhydryl groups.Maleimide is used to immobilize the bovine serum albumin-boronic acid conjugates in association with silica beads. Its nanoparticle surface favors the conjugation with cell penetration peptides. It is involved in Rhodium-catalyzed conjugate arylation with arylboronic acids. It is actively involved in Michael additions and Diels-Alder reactions by the addition across the double bond. It acts as crosslinking reagents in polymer chemistry.

备注
Store in a cool place. Incompatible with strong oxidizing agents, strong acids, strong bases and strong reducing agents.

基本信息

MDL
MFCD00005494

EINECS
208-787-4

分子式
C4H3NO2

分子量
97.07

熔点
90-94°

沸点
97-103/5mm

密度
1.249

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water.

Beilstein
106910

GHS危害和防范说明

GHS符号

Hazard Statements
H301-H314-H318-H317
Toxic if swallowed.Causes severe skin burns and eye damage.Causes serious eye damage.May cause an allergic skin reaction.

Precautionary Statements
P260h-P301+P310a-P303+P361+P353-P305+P351+P338-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
III

危险类别
25-34-43
Toxic if swallowed.Causes burns.May cause sensitization by skin contact.

安全等级
20-26-36/37/39-45-60
When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

RTECS
ON4800000

TSCA

129585Sigma-AldrichMaleimide99%641.05元/2 G;   1496.79元/10 G;   2097.21元/25 G;   展开

产品说明

一般描述

马来酰亚胺(2,5-吡咯二酮)是一种新型纳米颗粒表面官能团,易于与细胞穿透肽偶联。通过点击化学可实现偶联,同时保留其生物功能。

应用

铑催化的芳基硼酸共轭芳基化反应。
马来酰亚胺官能化二氧化硅颗粒可用于固定牛血清白蛋白(BSA)-硼酸(BA)偶联物。

包装

2 g in glass bottle
10, 25 g in poly bottle

基本信息

经验(实验)分子式C4H3NO2
分子量97.07
Beilstein106910
EC 号208-787-4
MDL编号MFCD00005494
PubChem化学物质编号24847914
NACRESNA.22

产品性质

质量水平100
测定99%
形式powder
mp91-93 ℃ (lit.)
SMILES stringO=C1NC(=O)C=C1
InChI1S/C4H3NO2/c6-3-1-2-4(7)5-3/h1-2H,(H,5,6,7)
InChI keyPEEHTFAAVSWFBL-UHFFFAOYSA-N

安全信息

象形图GHS05GHS06
警示用语:Danger
危险声明H300 - H314 - H317
预防措施声明P260 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
危险分类Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
个人防护装备Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
011793FluorochemMaleimide99%440元/5g;   1100元/25g;   2200元/100g;   4400元/250g;   展开

基本信息

CAS Number541-59-3
MDL NumberMFCD00005494
Melting Point90-94℃
Density1.4

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H314: Causes severe skin burns and eye damage.
H317: May cause an allergic skin reaction.
防范说明 P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P333 + P313: If skin irritation or rash occurs: Get medical advice/attention.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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