CAS 54-05-7; 氯喹盐基; 4-(4-Diethylamino-1-methylbntyla-mino)-7-chloroquinoline

CAS:

54-05-7

分子式:

C18H26ClN3

分子量:

319.89

沸点:

460.6°C

熔点:

87°C

中文名称:

氯喹盐基

4-(4-二乙氨基-1-甲基丁氨基)-7-氯喹啉

英文名称:

4-(4-Diethylamino-1-methylbntyla-mino)-7-chloroquinoline

Roquine

N4-(7-Chloro-4-quinolinyl)-N',N'-diethyl-1,4-pentane-diamine

7-chloro-4-((4-(diethylamino)-1-methylbutyl)amino)-quinolin

(7-chloro-4-(4-diethylamino-1-methylbutylamino)-quinoline

n(4)-(7-chloro-4-quinolinyl)-n(1),n(1)-diethyl-4-pentanediamine

1,4-pentanediamine, n(sup 4)-(7-chloro-4-quinolinyl)-n(sup 1),n(sup 1)-diethy

7-chloro-4-(4-diethylamino-1-methylbutylamino)quinoline

amokin

aralen

arthrochin

artrichin

bemaco

benaquin

bipiquin

capquin

chemochin

chloraquine

chlorochin

chloroquina

chloroquine

chloroquinium

chlorquin

cidanchin

clorochina

cocartrit

dichinalex

elestol

gontochin

heliopar

imagon

iroquine

klorokin

lapaquin

malaquin

malaren

malarex

mesylith

n(sup 4)-(7-chloro-4-quinolinyl)-n(sup 1),n(sup 1)-diethyl-1,4-pentanediamine

n4-(7-chloro-4-quinolinyl)-n1,n1-diethyl-1,4-pentanediamine

neochin

nivaquine b

quinachlor

quinagamine

quinercyl

quinilon

quinoscan

reumachlor

reumaquin

ronaquine

rp 3377

silbesan

siragan

sn 7618

solprina

sopaquin

tresochin

trochin

w 7618

win 244

展开更多英文名

性质描述:

该品为结晶体。熔点87-88℃，沸点212-214℃（27kPa）。本品的磷酸盐即抗疟药氯喹磷酸盐，为白色结晶性粉末，熔点193-195℃，易溶于水，不溶于乙醇、氯仿及乙醚。

生产方法:

由4,7-二氯喹啉（[86-98-6]）与2-氨基-5-二乙氨基戊烷缩合而得。

用途:

用与磷酸成盐，制取氯喹磷酸盐，它是一种主要用于控制疟疾症状的药物，也可用作抗阿米巴药物。对某些自身免疫性疾病，如类风湿关节炎、红斑狼疮、肾病综合症等亦有一定的作用。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

C798394

MACKLIN

氯喹

10mM in DMSO

129元/1ml; 388元/5ml;

咨询

储存：-20°C
状态：液体

C843545

MACKLIN

氯喹

97%

32元/50mg; 69元/250mg; 180元/1g; 750元/5g; 2800元/25g;

咨询

储存：2-8°C
状态：白色到浅黄色粉末

C3730

TCI

Chloroquine

>98.0%(T)(HPLC)

330元/250MG; 990元/1G;

咨询

基本信息

纯度/分析方法	>98.0%(T)(HPLC)
分子式/分子量	C₁₈H₂₆ClN₃ = 319.88
外观与形状(20℃)	固体
储存温度	0-10℃
储存在惰性气体下	存放于惰性气体之中
应避免的情况	空气,加热
包装和容器	1G-带有塑料内管的玻璃瓶 (查看图片), 250MG-带有塑料内管的玻璃瓶 (查看图片)
Reaxys-RN	482809
Merck Index (14)	2163
MDL编号	MFCD00024009

技术规格

Appearance	White to Light yellow powder to lump
Purity(HPLC)	min. 98.0 area%
Purity(Volumetric Analysis)	min. 98.0 %
Melting point	89.0 to 93.0 ℃
Specific rotation	-1.0 to +1.0 deg (C=1, methanol)
NMR	confirm to structure

物性(参考值)

熔点	91 ℃
最大吸收波长	228(H2O) nm

安全信息

图形或危害标志
信号词	警告
危险性说明	H302 : 吞咽有害。 H413 : 可能对水生生物造成长期持续有害影响。
防范说明	P501 : 将内装物/容器送到批准的废物处理厂处理。 P273 : 避免释放到环境中。 P270 : 使用本产品时不要进食、饮水或吸烟。 P264 : 作业后彻底清洗皮肤。 P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。

相关法规

RTECS#

VB2360000

242503

Fluorochem

N4-(7-Chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine

95%

1166元/250mg; 2706元/1g; 12584元/10g;

咨询

基本信息

CAS Number	54-05-7
MDL Number	MFCD00024009
Melting Point	87℃

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H332: Harmful if inhaled. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .