基本信息

技术规格

基本信息

安全信息

Technical Notes:

1. Introduced as an easier to handle Pd/P(t-Bu)3-based catalyst for the Negishi cross-coupling of aryl/vinyl chlorides.

2.A versatile catalyst for the cross- coupling of aryl and vinyl chlorides.

3.Catalyst for the amination of aryl chlorides and bromides using aqueous hydroxide bases.

4.UsefuI catalyst for the cross-coupling of heteroaromatic carboxylic acids.

5.Pd-catalyzed Newnan-Kwart rearrangement of o-aryl thiocarbamates.

6.Cross-coupling of silanolates and halides.

7.Elimination/isomerization of enol triflates derived from ß-ketoesters.

References:

1. J. Am. Chem. Soc., 2001, 123, 2719.

2. Handbook of Palladium Catalyzed Organic Reactions, 1997.

3.Palladium Reagents and Catalysis, 1995 (Tsuji).

4.J. Am. Chem. Soc.,2002，124，6343

5.J. Am. Chem. Soc., 2001, 123, 2719.

6.J. Org. Chem., 2002, 67, 6479.

7.J. Am. Chem. Soc., 2006, 128, 1 1350.

8.Angew. Chem. Int. Ed., 2009, 48, 7612.

9.J. Am. Chem. Soc., 2009, 131, 3104.

10. Angew. Chem. Int. Ed., 2011, 50, 6128.

应用
Bis(tri-tert-butylphosphine)palladium(0) is used in Coupling reactions, Heck couplings. It acts as a palladium catalyst for reductive carbonylation.

备注
Decomposes in water. Light, Air & Moisture Sensitive. Store at -20?°C.Do not store together with acids. Store in a cool, dry place in a tightly sealed container under nitrogen.

基本信息

MDL
MFCD03094580

分子式
C₂₄H₅₄P₂Pd

分子量
511.06

熔点
258-272°

灵敏度
Store at -20°C. Air Sensitive. Light Sensitive. Store under Argon.

形态
Powder, packaged under inert atmosphere

溶解性
Soluble in toluene benzene, slight soluble in chloroform and acetone. Decomposes in water.

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA
否

基本信息

Ref#
36350

MDL
03094580

分子式
C24 H54 P2 Pd

分子量
511.05

形态
Powder, packaged under inert atmosphere

基本信息

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .