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CAS: 52568-28-2
分子式: C8H12N2
分子量: 136.19
沸点: 212.7±15.0°C at 760 mmHg
中文名称: 
2-(吡啶-2-基)异丙胺
pip导向基团
shi辅基
英文名称: 
2-(pyridin-2-yl)isopropyl amine
pip directing group
shi auxilliary
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P895744MACKLIN2-(2-吡啶基)-2-丙胺95%88元/100mg;   110元/250mg;   350元/1g;   1300元/5g;   展开
储存:室温,避光干燥密封
状态:液体
802166Sigma-Aldrich2-(Pyridin-2-yl)isopropyl amine95% (GC)852.92元/500 MG;   展开

产品说明

一般描述

2-(吡啶-2-基)异丙基胺(PIP-胺)是一种叔胺。由PIP-胺已开发出可用于C-H键官能化的双齿导向基团。

应用

Shi助剂是一种通过铜介导的C-H 活化而使芳烃羟基化的导向基团。这种辅基可以通过酸介导的水解作用除去,并且已经证明可以进行克级规模的处理。

包装

500 mg in glass bottle

其他说明

铜催化双齿辅基导向芳烃和杂芳烃的羟基化反应

基本信息

经验(实验)分子式C8H12N2
分子量136.19
MDL编号MFCD08729302
PubChem化学物质编号329768731

产品性质

描述Fp: 175°F
质量水平100
测定95% (GC)
形式liquid
reaction suitabilityreagent type: ligand
reaction type: C-H Activation
折射率n/D 1.516
密度0.9800 g/mL at 25 ℃
SMILES stringNC(C)(C)C1=CC=CC=N1
InChI1S/C8H12N2/c1-8(2,9)7-5-3-4-6-10-7/h3-6H,9H2,1-2H3
InChI keyDQSQBZXDMHDHEO-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319
预防措施声明P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)175.0 °F
闪点(C)79.44 ℃
438176Fluorochem2-(Pyridin-2-yl)propan-2-amine95%1320元/250mg;   3190元/1g;   9658元/5g;   展开

基本信息

CAS Number52568-28-2
MDL NumberMFCD08729302
Density0.98

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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