CAS 5108-96-3; 四次甲基二硫代氨基甲酸铵; 1-pyrrolidinecarbodithioic acid ammoniumsalt

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A762203

MACKLIN

吡咯烷二硫代甲酸铵盐溶液

20g/L in H2O

150元/100ml; 520元/500ml;

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储存：2-8°C, 避光

A800469

MACKLIN

吡咯烷二硫代甲酸铵盐

99%

40元/1g; 57元/5g; 112元/25g; 405元/100g; 1578元/500g; 4895元/2.5kg;

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储存：2~8°C
状态：白色到灰白色或淡黄色粉末

A794593

MACKLIN

吡咯烷二硫代甲酸铵盐

10mM in DMSO

185元/1ml;

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储存：-20°C

A800325

MACKLIN

吡咯烷二硫代甲酸铵盐

95%

69元/25g; 209元/100g; 1022元/500g; 4584元/2.5kg;

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储存：2~8°C
状态：白色到淡黄色粉末,晶体和/或块状

P0644

TCI

Ammonium 1-Pyrrolidinecarbodithioate [Reagent for Atomic Absorption Analysis]

>95.0%(T)

445元/25G; 2585元/250G;

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基本信息

纯度/分析方法	>95.0%(T)
分子式/分子量	C₅H₁₂N₂S₂ = 164.29
外观与形状(20℃)	固体
储存温度	<0℃
储存在惰性气体下	存放于惰性气体之中
应避免的情况	空气,加热
Reaxys-RN	3730472
PubChem物质ID	87574803
MDL编号	MFCD00012720

技术规格

Appearance	White to Almost white powder to crystal
Purity(Iodometric Titration)	min. 95.0 %
Solubility in Water	very faint turbidity
Cadmium(Cd)	max. 1 ppm
Copper	max. 1 ppm
Zinc	max. 2 ppm
Iron	max. 5 ppm
Lead	max. 1 ppm
Sensitiveness	to pass test

物性(参考值)

熔点	144 ℃
水溶性	可溶
溶解性(可溶于)	乙醇,氯仿

安全信息

图形或危害标志
信号词	警告
危险性说明	H315 : 造成皮肤刺激。 H319 : 造成严重眼刺激。
防范说明	P264 : 作业后彻底清洗皮肤。 P280 : 戴防护手套/戴防护眼罩/戴防护面具。 P302 + P352 : 如皮肤沾染：用水充分清洗。 P337 + P313 : 如仍觉眼刺激：求医/就诊。 P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。 P332 + P313 : 如发生皮肤刺激：求医/就诊。

963743

J&K

1-Pyrrolidinecarbodithioic Acid Ammonium Salt

95%

371元/25G; 1015元/100G;

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基本信息

分子式	C₅H₁₂N₂S₂
分子量	164.29
熔点	153-155
MDL编码	MFCD00012720
Beilstein	3730472
EINECS 编号	225-834-4
存储条件	Store at 2-8℃

安全信息

图形或危害标志
提示语	Warning
危险说明	H315 H319 H335
防范说明	P261 P305+P351+P338
WGK	3

B23731

Alfa Aesar

1-Pyrrolidinecarbodithioic Acid Ammonium Salt

98%

1324元/25g; 3140元/100g;

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应用
1-Pyrrolidinecarbodithioic acid ammonium salt is useful for biochemical applications including metal chelation. It is used to prevent the induction of nitric oxide synthase. It is also essential to inhibit apoptosis in leukemia HL-60 cells.

备注
Hygroscopic. Air and light sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00012720

EINECS
225-834-4

分子式
C₅H₁₂N₂S₂

分子量
164.29

熔点
150-155°

灵敏度
Hygroscopic. Ambient temperatures.

形态
Powder

溶解性
Soluble in water.

Beilstein
3730472

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA
是

A182-10

Alfa Aesar

AMM PYRROL DITHIOCRBMATE 10G

914元/10g;

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基本信息

Ref#
F52177

P8765

Sigma-Aldrich

Ammonium pyrrolidinedithiocarbamate

~99%

463.45元/1 G; 1718.13元/5 G; 3814.98元/25 G; 7157.56元/100 G;

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产品说明

一般描述

吡咯烷二硫代甲酸铵盐是一种核因子κB (NF-κB)抑制剂。它作为一种螯合剂，可以从溶液中预浓缩痕量金属。吡咯烷二硫代甲酸铵盐(PDTC)具有抗氧化性质。它能抑制淋巴细胞、神经元和血管内皮细胞的凋亡。

应用

吡咯烷二硫代甲酸铵盐已被用于：

抑制人单核细胞中的核因子κB(NF-κB)动员和TNF(肿瘤坏死因子)产生
降低大鼠的中性粒细胞活性
防止阿霉素(ADR)处理的足细胞的Ca²⁺内流

消除人脑细胞中microRNA-146a启动子荧光素酶报告基因活性

包装

1, 5, 100 g in glass bottle

生化/生理作用

通过抑制 NOS mRNA 的翻译从而阻止一氧化氮合成酶的诱导；引发大鼠平滑肌细胞中的细胞凋亡并抑制白血病 HL-60 细胞中的细胞凋亡。

基本信息

线性分子式	C₅H₉NS₂ · NH₃
分子量	164.29
Beilstein	3730472
EC 号	225-834-4
MDL编号	MFCD00012720
PubChem化学物质编号	24278658
NACRES	NA.77

产品性质

质量水平	200
生物来源	microbial
测定	~99%
形式	powder
mp	153-155 ℃ (lit.)
溶解性	water: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
储存温度	2-8℃
SMILES string	N.SC(=S)N1CCCC1
InChI	1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3
InChI key	MDDIUTVUBYEEEM-UHFFFAOYSA-N
Gene Information	human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846), RELA(5970)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

09935

Sigma-Aldrich

Ammonium pyrrolidinedithiocarbamate

purum p.a., ≥98.0% (NT)

615.62元/25G; 1757.18元/100G; 9601.81元/1KG;

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产品说明

应用

用于从酸性溶液中沉淀砷、铋、镉、钴、铜、铁、锰、镍、铅、锑、锡、钒和锌等。

其他说明

采用有机溶剂从水溶液中提取和预富集重金属的试剂，以便进行原子吸收光谱 (AAS) 分析。MIBK(甲基异丁基酮)为所选溶剂；提取物可直接注入火焰中

基本信息

线性分子式	C₅H₉NS₂ · NH₃
分子量	164.29
Beilstein	3730472
EC 号	225-834-4
MDL编号	MFCD00012720
PubChem化学物质编号	329748864
NACRES	NA.21

产品性质

质量水平	200
等级	purum p.a.
测定	≥98.0% (NT)
形式	powder
mp	153-155 ℃ (lit.)
痕量阳离子	Bi: ≤10 mg/kg Ca: ≤10 mg/kg Cd: ≤10 mg/kg Co: ≤10 mg/kg Cr: ≤10 mg/kg Cu: ≤10 mg/kg Fe: ≤10 mg/kg K: ≤50 mg/kg Mg: ≤10 mg/kg Mn: ≤10 mg/kg Na: ≤50 mg/kg Ni: ≤10 mg/kg Pb: ≤10 mg/kg Zn: ≤10 mg/kg
SMILES string	N.SC(=S)N1CCCC1
InChI	1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3
InChI key	MDDIUTVUBYEEEM-UHFFFAOYSA-N
Gene Information	human ... RELA(5970)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

8.21100

Sigma-Aldrich

Pyrrolidine-1-dithiocarboxylic acid ammonium salt

for synthesis

427.03元/25 G; 1295.73元/100 G;

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产品说明

分析说明

Assay (HClO₄): ≥ 98.0 %
Identity (IR): passes test

基本信息

经验(实验)分子式	C₅H₁₂N₂S₂
分子量	164.29
MDL编号	MFCD00012720
EC索引号	225-834-4

产品性质

质量水平	200
pH值(酸碱度)	6-7 (20 ℃, 50 g/L in H₂O)
mp	146-151 ℃
溶解性	190 g/L
堆积密度	400 kg/m³
储存温度	2-8℃
InChI	1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3
InChI key	MDDIUTVUBYEEEM-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

548000

Sigma-Aldrich

1-Pyrrolidinecarbodithioic Acid, Ammonium Salt-CAS 5108-96-3-Calbiochem

Cell permeable. Inhibits the induction of NOS activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells.

922.52元/100 MG;

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产品说明

一般描述

Cell permeable. Inhibits the induction of nitric oxide synthase activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells. Inhibits NF-κB activation and HIV replication in lymphocytes.

包装

100 mg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
Induction of nitric oxide synthase activity in rat alveolar macrophages

警告

Toxicity: Irritant (B)

重悬

Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 3 months at -20°C.

From Catalog:

Desc. Field- added "cell-permeable"

其他说明

Tsai, J.C., et al. 1996. J. Biol. Chem.271, 3667.
Pan, Z., et al. 1995. J. Biol. Chem.270, 7787.
Bessho, R., et al. 1994. Biochem. Pharmacol.48, 1883.
Sherman, M.P., et al. 1993. Biochem. Biophys. Res. Commun.191, 1301.
Schreck, R., et al. 1992. J. Exp. Med.175, 1181.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₅H₁₂N₂S₂
分子量	164.29
MDL编号	MFCD00012720

产品性质

质量水平	100
测定	≥98% (titration)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated (hygroscopic)
颜色	white
溶解性	water: 1 mg/mL
运输	ambient
储存温度	2-8℃
InChI	1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3
InChI key	MDDIUTVUBYEEEM-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

240903

Fluorochem

Ammonium pyrrolidine-1-carbodithioate

95%

330元/5g; 638元/25g; 1870元/100g;

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基本信息

CAS Number	5108-96-3
MDL Number	MFCD00012720
Melting Point	144℃

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .