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CAS: 51-45-6
分子式: C5H9N3
分子量: 111.14
沸点: 167℃(0.8
熔点: 84-84℃
中文名称: 
组氨
组织胺
β-氨基乙基咪唑
β-氨乙基甘恶啉
组胺
英文名称: 
Histamine
1h-imidazole-4-ethanamine
2-(4-imidazolyl)ethylamine
4-imidazoleethylamine
5-imidazoleethylamine
beta-aminoethylglyoxaline
beta-aminoethylimidazole
beta-imidazolyl-4-ethylamine
eramin
ergamine
ergotidine
2-imidazol-4-yl-ethylamin
free histamine
4-(2-aminoethyl)-imidazol
imidazole-4-ethylamine
istamina
theramine
2-imidazol-4-ylethylamine
2-(1H-imidazol-4-yl)-ethylamine
2-1H-imidazol-4-yl-ethylamine
Histamin
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格详情
H811226MACKLIN组胺96%220元/1g;   886元/5g;   3502元/25g;   展开
储存:-20°C
状态:白色到黄色粉末
H795938MACKLIN组胺10mM in DMSO437元/1ml;   展开
储存:-20°C
268984J&KHistamine97%367元/1G;   1533元/5G;   展开

基本信息

分子式C5H9N3
分子量111.15
熔点83-84
沸点167
MDL编码MFCD00005210
Beilstein2012
Merck14,4719
EINECS 编号200-100-6
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Danger
危险说明H301
H315
H317
H319
H334
H335
防范说明P261
P280
P301+P310
P305+P351+P338
P342+P311
UN号码2811
危险分类6.1
包装等级III
WGK3
RTECSMS1050000
C41171Alfa AesarHistamine97%1436元/1g;   4864元/5g;   18800元/25g;   展开

基本信息

Ref#
41171

MDL
5210

分子式
C5 H9 N3

分子量
111.15

形态
Powder

安全信息

危险等级
6.1

包装组
III

H7125Sigma-AldrichHistamine≥97.0%1409.91元/1 G;   4640.64元/5 G;   14965.7元/25 G;   展开

产品说明

一般描述

组胺是由下丘脑后部神经元产生的神经递质。大脑中,组胺主要存在于灰质部分。

应用

组胺用于:

  • 刺激调节型细胞分泌
  • 在反应混合物中,活化血液,通过荧光测定法测定凝血酶(因子iia)活性
  • 填充腔室腔侧,研究其对TJ相关屏障的影响以及声带上皮中TJ(紧密连接)标志物的表达

包装

1, 5, 25 g in glass bottle

生化/生理作用

组胺参与先天免疫应答和获得性免疫应答,介导过敏和炎症。有助于肠道肌肉收缩。在过敏性休克过程中,组胺引起​​支气管收缩。组胺还参与分泌胃酸、控制上皮和内皮屏障。
内源性 H1 和 H2 组胺受体激动剂;H1 的活化可以使 Ca2+ 移动;H2 的活化可促进神经元中腺苷酸环化酶的活性;活化一氧化氮合成酶;有效的血管舒张剂。

基本信息

经验(实验)分子式C5H9N3
分子量111.15
Beilstein2012
EC 号200-100-6
MDL编号MFCD00005210
eCl@ss32160406
PubChem化学物质编号24895783
NACRESNA.77

产品性质

质量水平200
测定≥97.0%
bp167 ℃/0.8 mmHg (lit.)
mp83-84 ℃ (lit.)
储存温度−20℃
SMILES stringNCCc1c[nH]cn1
InChI1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChI keyNTYJJOPFIAHURM-UHFFFAOYSA-N
Gene Informationhuman ... CA1(759), CA2(760), HRH1(3269), HRH2(3274), HRH3(11255), HRH4(59340)
rat ... Hrh1(24448), Hrh3(85268)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H301 - H315 - H317 - H319 - H334 - H335
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
V900396Sigma-AldrichHistamineVetec, reagent grade, ≥97%507.68元/1 G;   2118.63元/5 G;   展开

产品说明

包装

5 g in glass bottle

生化/生理作用

内源性 H1 和 H2 组胺受体激动剂;H1 的活化可以使 Ca2+ 移动;H2 的活化可促进神经元中腺苷酸环化酶的活性;活化一氧化氮合成酶;有效的血管舒张剂。

法律信息

Vetec is a trademark of sigma-aldrich International GmbH

基本信息

经验(实验)分子式C5H9N3
分子量111.15
Beilstein2012
EC 号200-100-6
MDL编号MFCD00005210
PubChem化学物质编号329829805

产品性质

等级reagent grade
产品线Vetec
测定≥97%
bp167 ℃/0.8 mmHg (lit.)
mp83-84 ℃ (lit.)
储存温度−20℃
SMILES stringNCCc1c[nH]cn1
InChI1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChI keyNTYJJOPFIAHURM-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H301 - H315 - H317 - H319 - H334 - H335
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
3779MilliporeHistamine, Free Base-CAS 51-45-6-Calbiochem1349.79元/1 g;   展开

产品说明

一般描述

A potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase. Formed by the decarboxylation of L-histidine. Activation of histamine H1 receptors leads to Ca2+ mobilization, whereas histamine H2 receptor activation stimulates adenylate cyclase activity in neurons. Stimulated time- and concentration-dependent increase in p38 and p42/p44 MAP kinases in DDT(1) MF2 cells.
A potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase.
A potent vasodilator found in normal tissues and blood. Formed by the decarboxylation of L-histidine. Activates nitric oxide synthase (NOS), resulting in the release of nitric oxide. Activation of histamine H1 receptors leads to Ca2+ mobilization; whereas, histamine H2 receptor activation stimulates adenylate cyclase activity in neurons. Inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation.

包装

1 g in Glass bottle
5 g in Plastic ampoule
Packaged under inert gas

警告

Toxicity: Harmful (C)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Robinson, A.J., and Dickerson, J.M. 2001. Br. J. Pharmacol.133, 178.
Izumi, H., et al. 1995. Am. J. Obstet. Gynecol.172, 1477.
Vannier, E., and Dinarello, C.A. 1994. J. Biol. Chem.269, 9952.
Yan, Q.Z., et al. 1994. Agents Actions 41, C111.
Moncada, S., et al. 1991. Pharmacol. Rev. 43, 109.
Bloom, F.E. 1990. in Pharmacological Basis of Therapeutics p. 224 (Gilman, A.G., et al., Eds.) Pergamon Press, New York.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C5H9N3
分子量111.15
MDL编号MFCD00005210

产品性质

质量水平100
测定≥97% (TLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated (hygroscopic)
protect from light
颜色 white
溶解性water: 1 mg/mL
运输ambient
储存温度2-8℃
InChI1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChI keyNTYJJOPFIAHURM-UHFFFAOYSA-N

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H301 - H315 - H317 - H319 - H334 - H335
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
59964SupelcoHistamineanalytical standard950.94元/100 MG;   展开

产品说明

应用

有关理想仪器技术的更多信息,参见产品#8242;s分析证书。想要获得更多支持,请联系技术服务部。

生化/生理作用

内源性 H1 和 H2 组胺受体激动剂;H1 的活化可以使 Ca2+ 移动;H2 的活化可促进神经元中腺苷酸环化酶的活性;活化一氧化氮合成酶;有效的血管舒张剂。

基本信息

经验(实验)分子式C5H9N3
分子量111.15
Beilstein2012
EC 号200-100-6
MDL编号MFCD00005210
PubChem化学物质编号329758639
NACRESNA.24

产品性质

质量水平100
等级analytical standard
测定≥97.0% (TLC)
≥97.0% (anhydrous basis, NT)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
杂质≤4.0% water
颜色 white to light yellow
bp167 ℃/0.8 mmHg (lit.)
mp83-84 ℃ (lit.)
格式neat
储存温度−20℃
SMILES stringNCCc1c[nH]cn1
InChI1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChI keyNTYJJOPFIAHURM-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H301 - H315 - H317 - H319 - H334 - H335
预防措施声明P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
Y0001779HistamineEuropean Pharmacopoeia (EP) Reference Standard1259.15元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

内源性 H1 和 H2 组胺受体激动剂;H1 的活化可以使 Ca2+ 移动;H2 的活化可促进神经元中腺苷酸环化酶的活性;活化一氧化氮合成酶;有效的血管舒张剂。

包装

Unit quantity: 15mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C5H9N3
分子量111.15
Beilstein2012
MDL编号MFCD00005210
PubChem化学物质编号329831568
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
bp167 ℃/0.8 mmHg (lit.)
mp83-84 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度−20℃
SMILES stringNCCc1c[nH]cn1
InChI1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChI keyNTYJJOPFIAHURM-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H301 - H315 - H317 - H319 - H334 - H335
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
078943FluorochemHistamine96%880元/1g;   3300元/5g;   展开

基本信息

CAS Number51-45-6
MDL NumberMFCD00005210
Boiling Point167℃
Melting Point76-80℃

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H319: Causes serious eye irritation.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear .
P285: In case of inadequate ventilation wear respiratory protection.
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P304 + P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P333 + P313: If skin irritation or rash occurs: Get medical advice/attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342 + P311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
P362: Take off contaminated clothing and wash before reuse.
P363: Wash contaminated clothing before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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