| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| N793767 | MACKLIN | 去甲二氢愈创木酸 | 10mM in DMSO | 186元/1ml; | 展开 |
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| N828380 | MACKLIN | 去甲二氢愈创木酸 | 97% | 305元/250mg; 1099元/1g; 3385元/5g; | 展开 |
储存：室温 状态：白色到浅黄色和微米黄色到浅米黄色,粉末或晶体 |
| D0800 | TCI | Nordihydroguaiaretic Acid | >97.0%(HPLC) | 1090元/1G; 3460元/5G; | 展开 |
基本信息 | 纯度/分析方法 | >97.0%(HPLC) | | 分子式/分子量 | C18H22O4 = 302.37 | | 外观与形状(20℃) | 固体 | | Reaxys-RN | 9803564 | | PubChem物质ID | 87567422 | | SDBS (AIST Spectral DB) | 23619 | | Merck Index (14) | 6693 | | MDL编号 | MFCD00002206 |
技术规格 | Appearance | White to Orange to Green powder to crystal | | Purity(HPLC) | min. 97.0 area% | | Melting point | 185.0 to 189.0 ℃ |
物性(参考值) 安全信息 | 图形或危害标志 |  | | 信号词 | 警告 | | 危险性说明 | H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
| | 防范说明 | P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。
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相关法规 |
| 497666 | J&K | Nordihydroguaiaretic Acid | 95% | 186元/250MG; | 展开 |
基本信息 | 分子式 | C18H22O4 | | 分子量 | 302.36 | | 熔点 | 184-186 | | MDL编码 | MFCD00002206 | | Beilstein | 2056826 | | Merck | 14,6693 | | EINECS 编号 | 207-903-0 |
安全信息 | 图形或危害标志 | | | 提示语 | Warning | | 危险说明 | H302
H315
H319
H335 | | 防范说明 | P261
P305+P351+P338 | | WGK | 3 | | RTECS | UX1750000 | | TSCA | 否 |
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| 955860 | J&K | Nordihydroguaiaretic Acid | 98% | 900元/20MG; | 展开 |
基本信息 | 分子式 | C18H22O4 | | 分子量 | 302.36 | | MDL编码 | MFCD00002206 |
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| L03149 | Alfa Aesar | Nordihydroguaiaretic Acid | 97% | 907元/1g; 4118元/5g; | 展开 |
应用
Nordihydroguaiaretic acid is used in the treatment of multiple diseases, including cardiovascular diseases, neurological disorders and cancers. It is also used as an antioxidant. 备注
Incompatible with oxidizing agents. 基本信息 MDL
MFCD00002206 EINECS
207-903-0 分子式
C18H22O4 分子量
302.37 熔点
184-188° 灵敏度
Ambient temperatures. 形态
Powder 溶解性
Soluble in 100% ethanol, methanol, acetone, dimethylsulfoxide, dimethylformamide, ethanol (5% w/v), glycol, PEG, and slightly soluble in hot water. Insoluble in water. Beilstein
2056825 Merck
14,6693 GHS危害和防范说明 GHS符号
Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation. Precautionary Statements
P280h-P305+P351+P338
Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. 安全信息 危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin. 安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves. 欧盟危险品标志
 RTECS
UX1750000 TSCA
否 |
| C37630 | Alfa Aesar | Nordihydroguaiaretic Acid | 95% | 2710元/1g; 1750元/500mg; 10353元/5g; | 展开 |
基本信息 Ref#
37630 MDL
2206 分子式
C18 H22 O4 分子量
302.37 |
| 74540 | Sigma-Aldrich | Nordihydroguaiaretic Acid | ≥97.0% (HPLC) | 1431.4元/1 G; 4147.64元/5 G; | 展开 |
产品说明 一般描述 去甲二氢愈创木酸(NDGA)可用作抗氧化剂和活性氧(ROS)的强效清除剂。 应用 去甲二氢愈创木酸可用于： - 具有高HIV抑制活性的去甲二氢愈创木酸衍生物的合成。
- 作为合成四-O-甲基去甲二氢愈创木酸的起始原料。
包装 1, 5 g in glass bottle 生化/生理作用 脂氧合酶抑制剂；含多酚的邻二羟基(儿茶酚)结构。 其他说明 蚕豆脂氧合酶抑制剂 基本信息 | 线性分子式 | [-CH(CH3)CH2C6H3-1,2-(OH)2]2 | | 分子量 | 302.36 | | Beilstein | 2056826 | | EC 号 | 207-903-0 | | MDL编号 | MFCD00002206 | | PubChem化学物质编号 | 57652455 | | NACRES | NA.22 |
产品性质 | 质量水平 | 100 | | 测定 | ≥97.0% (HPLC) | | 杂质 | ≤2% water | | mp | 184-186 ℃ (lit.) | | SMILES string | CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2 | | InChI | 1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3 | | InChI key | HCZKYJDFEPMADG-UHFFFAOYSA-N | | Gene Information | mouse ... Alox12(11684) |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H319 - H335 | | 预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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| PHR3509 | Supelco | Nordihydroguaiaretic Acid | certified reference material, pharmaceutical secondary standard | 4676.2元/500 MG; | 展开 |
产品说明 一般描述 Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards 生化/生理作用 脂氧合酶抑制剂；含多酚的邻二羟基(儿茶酚)结构。 分析说明 These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. 其他说明 This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. 基本信息 | 线性分子式 | [-CH(CH3)CH2C6H3-1,2-(OH)2]2 | | 分子量 | 302.36 | | Beilstein | 2056826 | | MDL编号 | MFCD00002206 |
产品性质 | 等级 | certified reference material
pharmaceutical secondary standard | | 描述 | Pharmaceutical Secondary Standard; Certified Reference Material | | 形式 | crystals | | 包装 | pkg of 500 mg | | mp | 184-186 ℃ (lit.) | | 储存温度 | -10 to -25℃ | | SMILES string | CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2 | | InChI | 1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3 | | InChI key | HCZKYJDFEPMADG-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H319 - H335 | | 预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| PHL82880 | | Nordihydroguaiaretic Acid | phyproof® Reference Substance | 3048.57元/50 MG; | 展开 |
产品说明 一般描述 This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG 生化/生理作用 脂氧合酶抑制剂；含多酚的邻二羟基(儿茶酚)结构。 法律信息 phyproof is a registered trademark of PhytoLab GmbH & Co. KG 基本信息 | 线性分子式 | [-CH(CH3)CH2C6H3-1,2-(OH)2]2 | | 分子量 | 302.36 | | Beilstein | 2056826 | | MDL编号 | MFCD00002206 |
产品性质 | 等级 | primary reference standard | | 产品线 | phyproof® Reference Substance | | 测定 | ≥98.0% (HPLC) | | manufacturer/tradename | PhytoLab | | mp | 184-186 ℃ (lit.) | | application(s) | food and beverages | | 格式 | neat | | SMILES string | CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2 | | InChI | 1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3 | | InChI key | HCZKYJDFEPMADG-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H319 - H335 | | 预防措施声明 | P261 - P264 - P280 - P304 + P340 + P312 - P337 + P313 - P403 + P233 | | 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 479975 | Sigma-Aldrich | NDGA-CAS 500-38-9-Calbiochem | A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC₅₀ = 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC | 1164.01元/250 MG; | 展开 |
产品说明 一般描述 A cell-permeable, antioxidant and a selective lipoxygenase (LO) inhibitor (IC50 = 200 nM, 30 µM, and 30 µM for 5-LO, 12-LO, and 15-LO, respectively) over cyclooxygenase (IC50 = 100 µM). Also shown to inhibit platelet-derived growth factor (PDGF)-stimulated DNA synthesis in Swiss 3T3 cells.
A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC50 = 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC50 = 100 µM). Also shown to inhibit platelet-derived growth factor (PDGF)-stimulated DNA synthesis in Swiss/3T3 cells. A powerful hydroxy radical quencher. 包装 250 mg in Glass bottle 生化/生理作用 Cell permeable: yes
Target IC50: 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively
Primary Target
LOX-5
Product does not compete with ATP.
Reversible: no 警告 Toxicity: Harmful (C) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 其他说明 Domin, J., et al. 1994. J. Biol. Chem. 269, 8260.
Goodman, Y., et al. 1994. Brain Res. 654, 171.
Kozubik, A., et al. 1993. Exp. Hematol. 21, 138.
Salari, H., et al. 1984. Prostagland. Leuk. Med. 13, 53.
Hope, W.C., et al. 1983. Biochem. Pharmacol. 32, 367. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息 | 经验(实验)分子式 | C18H22O4 | | 分子量 | 302.36 | | MDL编号 | MFCD00002206 |
产品性质 | 质量水平 | 100 | | 测定 | ≥90% (HPLC) | | 形式 | crystalline solid | | manufacturer/tradename | Calbiochem® | | 储存条件 | OK to freeze | | 溶解性 | DMSO: 10 mg/mL
ethanol: soluble | | 运输 | ambient | | 储存温度 | 10-30℃ | | InChI | 1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+ | | InChI key | HCZKYJDFEPMADG-TXEJJXNPSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H319 - H335 | | 预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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