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CAS: 50-89-5
分子式: C10H14N2O5
分子量: 242.23
熔点: 186-188 °C(lit.)
中文名称: 
2'-脱氧胸苷
β-胸腺嘧啶核苷
胸苷
β-胸苷
英文名称: 
Thymidine
2'-deoxythymidine
5-methyldeoxyurindine
deoxythymidine
dthyd
thymidin
thymine-2-deoxyriboside
thyminedeoxyriboside
Thymidine-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil
Beta-Thymidine
β-Thymidine
展开更多英文名
用途: 医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
T818924MACKLINβ-胸苷(dT)99%26元/1g;   32元/5g;   51元/25g;   140元/100g;   668元/500g;   1299元/1kg;   咨询
储存：2~8°C
状态：白色到浅黄色粉末
折射率：33 ° (C=1, 1mol/L NaOH)
T0233TCIThymidine>98.0%(T)(HPLC)125元/1G;   310元/5G;   860元/25G;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C10H14N2O5 = 242.23
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (吸湿)
Reaxys-RN89285
PubChem物质ID87576219
SDBS (AIST Spectral DB)1178
Merck Index (14)9397
MDL编号MFCD00006537

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Melting point186.0 to 190.0 ℃
Specific rotation [a]20/D+32.0 to +34.0 deg(C=1, 1mol/L NaOH sol.)
Solubility in Wateralmost transparency

物性(参考值)

熔点186 ℃
比旋光度 [α]D33° (C=1,1mol/L NaOH sol.)

相关法规

RTECS#XP2071000
144001J&KThymidine99%60元/1G;   95元/5G;   223元/25G;   咨询

基本信息

分子式C10H14N2O5
分子量242.23
熔点187-189
MDL编码MFCD00006537
Beilstein89285
Merck14,9397
EINECS 编号200-070-4

安全信息

图形或危害标志
提示语Danger
危险说明H316
H320
H335
H340
防范说明P280
P305+P351+P338
WGK3
RTECSXP2071000
TSCA否
A11493Alfa AesarThymidine99%522元/5g;   2155元/25g;   4223元/100g;   咨询

应用
Thymidine is used in the syntheses of active pharmaceutical ingredient such as zidovudine. It also pairs with deoxyadenosine in double-stranded deoxyribonucleic acid. It is used to synchronize the cells in G1/early S phase in cell biology.

备注
Store in a cool place. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00006537

EINECS
200-070-4

分子式
C10H14N2O5

分子量
242.23

熔点
186-190°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in water, methanol, hot ethanol, hot acetone, hot ethyl acetate, pyridine, glacial acetic acid and hydrochloric acid. Slightly soluble in hot chloroform .

Beilstein
89285

Merck
14,9397

安全信息

RTECS
XP2071000

TSCA
是

T1895Sigma-AldrichThymidinepowder, BioReagent, suitable for cell culture562.74元/1 G;   1945.86元/5 G;   3600.18元/10 G;   7777.79元/25 G;   咨询

产品说明

一般描述

胸苷又称为嘧啶脱氧核苷。脱氧胸苷是DNA中存在的核苷。在DNA双链结构中，胸苷与脱氧腺苷配对。

应用

胸苷可用在HT和HAT混合物中，用于杂交瘤融合、筛选和克隆。它已用于：

  • 用作基础培养基中的核苷酸来源，以评估iSCNT分化胚泡的生长
  • 作为杜氏改良Eagle培养基(DMEM)选择培养基的补充成分，用于制备抗神经素(NRGN)抗体
  • 用于制备THMG(胸腺嘧啶、次黄嘌呤、甘氨酸、甲氨蝶呤)和THG储备液，清洁小鼠淋巴瘤细胞

包装

1, 5, 10, 25 g in poly bottle

生化/生理作用

胸苷可用于S期细胞同步。在嘧啶的补救合成途径中，嘧啶磷酸化酶将胸腺嘧啶可逆转化为胸苷。

基本信息

经验(实验)分子式C10H14N2O5
分子量242.23
Beilstein89285
EC 号200-070-4
MDL编号MFCD00006537
PubChem化学物质编号24899996
NACRESNA.75

产品性质

质量水平200
生物来源synthetic (organic)
产品线BioReagent
测定≥99%
形式powder
technique(s)cell culture | mammalian: suitable
mp186-188 ℃ (lit.)
溶解性water: 50 mg/mL, clear, colorless
web metadata keyword.defaultcomponent of HT medium, component of HAT medium, hybridoma fusion protocols
SMILES stringCC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChI keyIQFYYKKMVGJFEH-XLPZGREQSA-N
Gene Informationhuman ... DTYMK(1841)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
T9250Sigma-AldrichThymidine≥99%382.38元/1 G;   1149.82元/5 G;   2315.62元/10 G;   4647.23元/25 G;   咨询

产品说明

一般描述

胸苷又称为嘧啶脱氧核苷。脱氧胸苷是DNA中存在的核苷。在DNA双链结构中，胸苷与脱氧腺苷配对。在S阶段的细胞同步中起作用。在嘧啶的补救合成途径中，嘧啶磷酸化酶将胸腺嘧啶可逆转化为胸苷。

应用

胸苷可用于：

  • HL5修饰培养基的补充剂 用于细胞培养
  • 在细胞周期分析中进行细胞孵育
  • 用于细胞同步

包装

1, 5, 10, 25 g in poly bottle

基本信息

经验(实验)分子式C10H14N2O5
分子量242.23
Beilstein89285
EC 号200-070-4
MDL编号MFCD00006537
PubChem化学物质编号24900588
NACRESNA.51

产品性质

质量水平200
生物来源synthetic (organic)
测定≥99%
形式powder
mp186-188 ℃ (lit.)
溶解性water: 50 mg/mL, clear, colorless
SMILES stringCC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChI keyIQFYYKKMVGJFEH-XLPZGREQSA-N
Gene Informationhuman ... DTYMK(1841)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
89270Sigma-AldrichThymidine≥99.0% (HPLC)647.52元/1 G;   1362.99元/5 G;   5482.6元/25 G;   咨询

产品说明

应用

胸苷 (dT) 是一种嘧啶脱氧核苷(脱氧核苷)，在连续磷酸化为脱氧胸苷三磷酸 (dTTP) 后用于合成 DNA 和转移 RNA 的 T 环。胸苷作为胸苷激酶 EC 2.7.1.21 的底物，胸苷激酶 EC 2.7.1.21 用 ATP 衍生的磷酸磷酸化核苷。dT 可用于研究胸苷激酶家族的分布、特异性和动力学。

基本信息

经验(实验)分子式C10H14N2O5
分子量242.23
Beilstein89285
EC 号200-070-4
MDL编号MFCD00006537
PubChem化学物质编号329769717
NACRESNA.51

产品性质

质量水平200
生物来源synthetic
测定≥99.0% (HPLC)
形式powder
旋光性[α]20/D +19±1°, c = 1% in H2O
mp185-190 ℃
186-188 ℃ (lit.)
溶解性hot water: 1 g/10 mL
SMILES stringCC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChI keyIQFYYKKMVGJFEH-XLPZGREQSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
V900391Sigma-AldrichThymidineVetec™, reagent grade, 99%143.89元/1 G;   574.24元/5 G;   咨询

产品说明

包装

1, 5 g in poly bottle

法律信息

Vetec is a trademark of sigma-aldrich International GmbH

基本信息

经验(实验)分子式C10H14N2O5
分子量242.23
Beilstein89285
EC 号200-070-4
MDL编号MFCD00006537
PubChem化学物质编号329829801

产品性质

等级reagent grade
产品线Vetec™
测定99%
形式powder
mp186-188 ℃ (lit.)
溶解性water: 50 mg/mL, clear, colorless
SMILES stringCC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChI keyIQFYYKKMVGJFEH-XLPZGREQSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1724543USPZidovudine Related Compound DUnited States Pharmacopeia (USP) Reference Standard12669.8元/50 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C10H14N2O5
分子量242.23
Beilstein89285
MDL编号MFCD00006537
PubChem化学物质编号329751282
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp186-188 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChI keyIQFYYKKMVGJFEH-XLPZGREQSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
6060MilliporeThymidine-CAS 50-89-5-Calbiochem1116.04元/5 g;   咨询

产品说明

一般描述

Used in conjunction with hypoxanthine and aminopterin for the selection of hybridoma cell lines. Also reported to induce cell death in L-cells.

包装

5 g in Plastic ampoule

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, sterilize by filtration using a 0.22 µm filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.

其他说明

Amenta, J.S., et al. 1993. In Vitro Cell Dev. Biol. Anim.29A, 855.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C10H14N2O5
分子量242.23
MDL编号MFCD00006537

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 white
溶解性water: 10 mg/mL
痕量阳离子heavy metals: ≤10 ppm
运输ambient
储存温度10-30℃
InChI1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)
InChI keyIQFYYKKMVGJFEH-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR3163SupelcoZidovudine Related Compound Dpharmaceutical secondary standard6205.72元/100 mg;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C10H14N2O5
分子量242.23
Beilstein89285
MDL编号MFCD00006537

产品性质

等级pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 100 mg
mp186-188 ℃ (lit.)
application(s)pharmaceutical
药典可追溯性traceable to USP 1724543
储存温度2-8℃
SMILES stringCC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChI keyIQFYYKKMVGJFEH-XLPZGREQSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
995003AmethystThymidine99%, 用于生化40元/5G;   119元/25G;   301元/100G;   咨询

基本信息

分子式C10H14N2O5
分子量242.23
熔点187-189
MDL编码MFCD00006537
Beilstein89285
Merck14,9397
EINECS 编号200-070-4

安全信息

图形或危害标志
提示语Danger
危险说明H316
H320
H335
H340
防范说明P280
P305+P351+P338
WGK3
RTECSXP2071000
TSCA否
078885FluorochemThymidine98%220元/5g;   330元/10g;   528元/25g;   1760元/100g;   咨询

基本信息

CAS Number50-89-5
MDL NumberMFCD00006537
Melting Point186-188 ℃(lit.)

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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