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CAS: 50-34-0
分子式: C23H30BrNO3
分子量: 448.42
中文名称: 
溴化丙胺太林
普鲁本辛
溴丙胺太林
英文名称: 
propanthelinebromide
ammonium, diisopropyl(2-hydroxyethyl)methyl-, bromide, xanthene-9-carboxylate
2-propanaminium, n-methyl-n-(1-methylethyl)-n-[2-[(9h-xanthen-9-ylcarbonyl)oxy]
diisopropyl(2-hydroxyethyl)methylammonium bromide xanthene-9-carboxylate
ercorax
ercotina
ketaman
kivatin
nci-c56257
neometantyl
neopepulsan
pantas
pantheline
pervagal
pro-banthine
pro-gastron
prodixamon
propantel
propantheline bromide
sc-3171
xanthene-9-carboxylic acid, ester with (2-hydroxyethyl)diisopropylmethylammon
ium bromide
Probanthine
展开更多英文名
性质描述: 白色或类白色结晶性粉末。熔点159-161℃。易溶于水、乙醇或氯仿,不溶于乙醚。无臭,味极苦。
生产方法: 呫吨-9-羧酸与二异丙氨基乙醇在二甲苯中酯化,于137-140℃脱水反应10h。反应毕,加活性炭脱色,冷却至0℃,压滤,滤液减压回收二甲苯及过剩的二异丙氨基乙醇,得呫吨-9-羧酸-β-二异丙氨基乙酯。然后与溴甲烷进行成季铵盐反应,制得溴化丙胺太林。
用途: 抗胆碱解痉药,与阿托品具有相似的作用。适用于胃及十二指肠溃疡、胃炎、胰腺炎、肠痉挛、多汗和妊娠呕吐等。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P873668MACKLIN溴丙胺太林98%30元/5mg;   64元/25mg;   84元/100mg;   144元/1g;   479元/5g;   展开
储存:-20℃
状态:白色到灰白色粉末
P798229MACKLIN溴丙胺太林10mM in DMSO185元/1ml;   展开
储存:-20°C
P8891Sigma-AldrichPropantheline bromide≥97% (TLC), powder732.6元/5 G;   2716.78元/25 G;   展开

产品说明

包装

5, 25 g in poly bottle

生化/生理作用

Inhibits action of acetylcholine at post-ganglionic synapses; muscarinic acetylcholine receptor antagonist; antispasmodic; reduces gastric acid secretion.

特点和优势

This compound was developed by Shire. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

线性分子式C23H30NO3Br
分子量448.39
EC 号200-030-6
MDL编号MFCD00050291
PubChem化学物质编号24278660
NACRESNA.77

产品性质

质量水平200
测定≥97% (TLC)
形式powder
颜色 white to off-white
溶解性H2O: 50 mg/mL
创始人Shire
SMILES string[Br-].CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C
InChI1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1
InChI keyXLBIBBZXLMYSFF-UHFFFAOYSA-M
Gene Informationhuman ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
1570508USPPropantheline bromideUnited States Pharmacopeia (USP) Reference Standard3036.37元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Inhibits action of acetylcholine at post-ganglionic synapses; muscarinic acetylcholine receptor antagonist; antispasmodic; reduces gastric acid secretion.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式C23H30NO3Br
分子量448.39
MDL编号MFCD00050291
PubChem化学物质编号329750979

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES string[Br-].CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C
InChI1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1
InChI keyXLBIBBZXLMYSFF-UHFFFAOYSA-M
Gene Informationhuman ... CHRM1(1128), CHRM2(1129), CHRM3(1131)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR1575SupelcoPropantheline bromidePharmaceutical Secondary Standard; Certified Reference Material1518.26元/500 MG;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Propantheline Bromide belongs to the class of quaternary ammonium compounds and is a synthetic anticholinergic drug. It is widely used as an oral agent and it exhibits antimuscarinic effect in the lower urinary tract.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

Inhibits action of acetylcholine at post-ganglionic synapses; muscarinic acetylcholine receptor antagonist; antispasmodic; reduces gastric acid secretion.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA4491 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式C23H30NO3Br
分子量448.39
EC 号200-030-6
MDL编号MFCD00050291
PubChem化学物质编号329823483
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1570508
储存温度2-8℃
SMILES string[Br-].CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C
InChI1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1
InChI keyXLBIBBZXLMYSFF-UHFFFAOYSA-M
Gene Informationhuman ... CHRM1(1128), CHRM2(1129), CHRM3(1131)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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